2510results about How to "Avoid cross contamination" patented technology

A microfluidic device for analyzing and / or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are useful for sorting particles, e.g. virions. The invention is also useful for high throughput screening, e.g. combinatorial screening. The microfluidic device comprises a main channel and an inlet region in communication with the main channel at a droplet extrusion region. Droplets of solution containing the biological material are deposited into the main channel through the droplet extrusion region. A fluid different from and incompatible with the solution containing the biological material flows through the main channel so that the droplets containing the biological material do not diffuse or mix. Biological material within the droplets can be analyzed and / or sorted by detecting a predetermined characteristic of the biological sample in each droplet and sorting the droplet accordingly.

A portable medical diagnostic instrument includes an instrument head and a handle portion having an open-ended receiving cavity. A compact illuminator defined by a housing retaining a miniature light source and a power supply is releasably fitted within the open-ended receiving cavity of the handle portion wherein the light source of the illuminator is optically coupled with the instrument on assembly therewith. The handle portion can be integral with the instrument or releasably attached. The handle portion according to at least one version is made from a plastic or other suitable material, permitting disposability and / or single patient use. In one version, the handle portion is flexibly deformable, at least partially, to facilitate release of the portable illuminator.

A beverage dispensing system including a control unit and a touch screen. Inputs are made to the touch screen to dispense beverages and apply system adjustments. The control unit controls a plurality of beverage dispensing valves according to inputs made to the touch screen.

The present invention relates to new methods for manufacturing photovoltaic devices and an apparatus for practicing those methods of manufacture. The present invention employs a transfer-through system for advancing work piece substrates through an integrated apparatus of multiple treatment chambers that control each of the manufacturing processes.

A hypodermic syringe and a plurality of single use cartridges able to be successively loaded into said syringe for providing rapid dispensing of a medicant to numerous users without possibility of contamination. The cartridges are continuously fed through the syringe for the quick and efficient inoculation of patients. An operator inserts a needle into a patient by pushing in a trigger. Prior to the needle being inserted into the patient, a disinfectant is dispersed from the cartridge to maintain sterility. An operator then pushes in a plunger forcing the medication through the needle into the patient. The plunger is pulled back into its original location after use. The needle is pulled back with the plunger out of the patient's skin and back into the cartridge. A new cartridge on a clip is then advanced into the syringe for use in inoculating the next patient needing medication. The syringe and cartridge dispenser further maintains a sterile environment during successive vaccinations reducing the transmission of any disease from patient to patient.

The present invention relates to pharmaceutical compositions for the treatment and / or prophylaxis of disease associated with fibrosis in a vertebrate, said composition comprising at least one activin antagonist, and optionally a pharmaceutically acceptable carrier, adjuvant and / or diluent. The invention also relates to methods of treatment of disease associated with fibrosis in a vertebrate, as well as methods for diagnosing such conditions, and kits therefor.

A protective sheet loader may comprise a first roller, a second roller, a sheet of material spanning between the first and second rollers, and a loading mechanism. A portion of the sheet of material may be loaded into the crimping chamber of an apparatus for reducing the size of a medical device. A medical device may be placed within the crimping chamber such that the sheet of material forms a barrier between the walls of the crimping chamber and the medical device and prevents cross-contamination between the medical device and the crimping device. After a crimping step is completed, the medical device and the contaminated portion of the sheet of material may be removed from the crimping chamber, and a clean portion of the sheet of material may be loaded into the crimping chamber.

An antibacterial / anti-inflammatory composition and method wherein the pairing of synergistic active ingredients with a natural enhancer for a more efficacious formulation for topical application treatments is used. Active ingredients hydrocortisone 1% and benzoyl peroxide 10% are paired with Emu Oil to increase the percentage of absorption of the ingredients through the skin. The preferred method of use of the composition is via a dual-pharmaceutical delivery syringe that isolates components (1) having a barrel (9), a piston (8) and a commonly shared split nozzle (5). The barrel (9) has two syringe compartments (2) and (14) attached to one another and connected to the split nozzle (5). The piston (8) has two plungers (6) connected via a bridge (12). A user applies force to the piston (8), dispersing the substances in the syringe compartments (2) and (14) through the respective sides of the split nozzle (5) onto the user's skin. The user then massages the substances into the skin for “hands-on healing.”

Reconfigurable control systems for beverage dispensers, beverage dispensers with a reconfigurable control panel, beverage dispensers that sequence the dispensing of beverage fluids that make up a selected beverage, beverage dispensers that allow for the dispensing of user customized beverages, and related methods for dispensing a beverage fluid are provided. A reconfigurable control system includes a control panel having multiple sensing regions, user reconfigurable switches used to select a control panel configuration, and a control unit operatively coupled with the control panel and the user reconfigurable switches. Each of the sensing regions is assigned to a key of the selected control panel configuration or deactivated. The keys of the selected control panel configuration receive user input to select a beverage and / or a beverage additive.

This invention comprises an apparatus for the deposition of thin layers upon a substrate for the production of photovoltaic cells wherein the individual reaction chambers are separated from each other by low pressure isolation zones which prevent cross contamination of adjacent reaction chambers and control pressure levels in each reaction chamber while, at the same time, allowing the uninterrupted transfer of a substrate from one reaction chamber to the next without any mechanical obstruction.

Provided is a device for concentrating and separating cells, which has a function for continuously concentrating cells; a function for then continuously arranging the concentrated cells in predetermined regions of a flow path; a function for simultaneously identifying shape and fluorescent emission in one-cell units on the basis of cell concentration and purification images, which serve to continuously separate and purify cells that have different properties in that they are either attracted to or repelled by an induction electrophoresis force of a predetermined frequency; and a function for identifying cells on the basis of this shape and fluorescent emission information and thereby separating and purifying the cells.

The present invention provides material removal heads and devices for noninvasively removing materials from the wells of multi-well plates. The material removal heads of the invention are structured to prevent cross-contamination among wells of multi-well plates as materials are removed from the plates. The invention also provides dispense heads and devices that include angled dispensers. Related systems, kits, and methods are additionally provided.

A monitoring network system for inspecting and controlling harmful substances includes probe assemblies that each includes a sensor comprising nano structured surfaces or nano particles in a solution, configured to adsorb molecules of a sample material captured adjacent to the sensor, a laser that can emit a laser beam to illuminate the molecules adsorbed to the nano structured surfaces, a spectrometer that can produce spectral data from light scattered by the molecules adsorbed to the nano structured surfaces, and a ID reader that can retrieve identification information about the sample material. A central office can determine a spectral signature matching spectral signatures stored in a database and to identify a harmful substance in the sample material. An alert and response system can send out an alert signal about the sample material when the harmful substance is identified in the sample material.

The invention discloses a full-automatic immuno-fluorescence quantitative analysis device and an implementation method, belonging to the field of quantitative immuno-fluorescence analysis and detection. The full-automatic immuno-fluorescence quantitative analysis device comprises a supporting bottom plate, a reagentstrip storage and automatic loading module, a reactiondisc module, a detection module, a sample module, a sample adding module, a washing module and a control system, wherein the reagentstrip storage and automatic loading module, the reactiondisc module, the detection module, the sample module, the sample adding module and the washing module are arranged on the supporting bottom plate in sequence; the reagentstrip storage and automatic loading module provides a reagent strip for the reactiondisc module; the sample adding module is used for adding samples in the sample module into the reactiondisc module to carry out reaction, and after reaction is finished, the samples enter the detection module to be detected. The full-automatic immuno-fluorescence quantitative analysis device and the implementation method disclosed by the invention have the advantages that the difficulty that automation is hard to implement for an in-vitro diagnosis product is solved, the artificial error is reduced, the testing accuracy is improved and the detection efficiency is improved.

Apparatus for producing a serving of frozen confectionery product is characterized by a supply of liquid gas, a support for removably carrying a disposable container that holds a volume of unfrozen confectionery mix, and a holder for releasably holding a disposable agitator, such that the agitator extends into confectionery mix in the container. A valve controllably dispenses liquid gas into the confectionery mix in the container while relative motion is imparted to the container and agitator to agitate and admix the confectionery mix and liquid gas while the liquid gas mix evaporates to cool and freeze the confectionery mix, through a transfer of heat from the confectionery mix to the liquid gas and through the latent heat of evaporation of the liquid gas, to produce the frozen confectionery product.

An insulated cooler with two (2) separate independent storage compartments and lids allowing for compartmentalized transportation and storage of items is herein disclosed. The separate compartments eliminate possible cross-contamination as well as provide different thermal conditioning of the contents. The compartments are completely independent of each other having an interior divider wall extending completely through the body of the cooler and continuing into a lid area, thereby sealing independent compartments. Additionally, each compartment is also provided with a draining means.

The invention discloses a butt joint type operation patient transfer trolley and belongs to the technical field of medical apparatus. The butt joint type operation patient transfer trolley comprises a transverse moving bed and a transfer trolley. The transverse moving bed with a tiltable bed top is disposed on a transfer trolley plate of the transfer trolley and locked by a bed locking device. The transfer trolley comprises a transfer trolley body, a transfer trolley base and a lifting device. The transfer trolley body is supported on the transfer trolley base through the lifting device. The transverse moving bed mainly comprises a transverse moving bed frame, a bed board, an air cushion and rollers. Inflation of the air cushion enables the bed board to tilt. By the butt joint technology, an operation patient along with the moving bed is transferred from the transfer trolley outside an operating room to the transfer trolley in the operating room, cross infection is avoided, operating environments are kept clean, and operating safety is increased. By the moving bed with the tiltable bed top, the patient can be transferred from the operation patient transfer trolley to an operating table conveniently and time- and labor-savingly. The butt joint type operation patient transfer trolley is suitable for transferring seriously-injured patients from ambulances to operating rooms of hospitals.

The invention relates to the field of medical apparatus and instruments, and in particular, relates to a multi-channel fully automatic blood type analyzer cooperatively used with a microcolumn gel card. The multi-channel fully automatic blood type analyzer includes an analyzer base; a working platform is fixed on the base; the working platform is provided with a sample adding, picking and placing mechanism and a reagent storage mechanism; the sample adding, picking and placing mechanism includes a sample adding mechanical arm and a grasping mechanical arm; the middle part of the working platform is provided with a plurality of groups of loading tracks, the loading tracks are loaded with a sample loading frame, a self-use evenly-mixing reagent loading frame, a gun head loading frame and a microcolumn gel card loading frame in turn side by side. The multi-channel fully automatic blood type analyzer is small in size and compact in design, and flexibly meets the multiple experimental functions of the system. The mechanical arms have high transmission accuracy and long service life.

The invention relates to a pipette sampling system that allows for automated sampling from the contents of a capped sample tube. More specifically, the invention relates to a pipette tip, having a piercing tip attached thereto, for removal of aliquots of samples from capped sample tubes comprising said samples.

The invention provides an integrated flow path chip device used for digital nucleic acid amplification. The device is composed of a vacuum system, a pipeline, a sucker, a sealing cover layer and a reaction layer, wherein two ends of the sealing cover layer are respectively provided with a sample inlet and a sample outlet; a path is formed between the sealing cover layer and the reaction layer; the reaction layer is provided with small reaction chambers; the sucker is arranged on the sample outlet; the vacuum system is connected with the sucker via a pipeline; and the sample inlet and the sample outlet are sealed by adhesive tape paper. According to the integrated flow path chip device, trace reaction samples can be distributed to thousands of small reaction chambers, and mineral oil is led in via a path in the sealing cover layer to separate thousands of small reaction chambers so as to realize the single molecule amplification and precisely quantify the nucleic acid molecules. The device is reasonable to design and is a minitype device used for digital nucleic acid amplification, which has low cost and is easy to operate.

The invention discloses an automated instrument applied to nucleic acid extraction and continuous operation process of a mass spectrum sample application chip in biomass spectrometry analysis of a nucleic acid sample. The automated instrument comprises three main devices, namely, a nucleic acid extraction and purification device, a nucleic acid liquor relief distributing device and a mass spectrum chip sample application device, wherein nucleic acid in body fluid is extracted by using a magnetic bead method, a mechanical arm is utilized to complete a nucleic acid extraction action, the extracted nucleic acid is dispensed onto a sample board through a dispenser, a pipettor is used for transferring the sample board onto a chip sample application instrument, and the mass spectrum and relatedinformation of the nucleic acid are obtained through laser sampling of a mass spectrometer, so that the nucleic acid is analyzed rapidly, directly and continuously. The automated instrument is high-precision in controlling the volume of dispensed liquor, high-cleanliness in controlling the quality of the dispensed liquor and high-efficiency in meeting sample application requirements of large-batch samples; meanwhile, the samples are uniformly distributed under the control of a computer program, volume errors and possible foreign pollution caused by manual operation are avoided, and the speed and efficiency in sample application are increased at the same time.

The invention relates to a method for separating and extracting stem cells from a placenta, umbilical cord or adipose tissue, which comprises the following process steps: firstly mixing the placenta, umbilical cord or adipose tissue and a cell maintenance fluid according to the proportion by weight of 2.5-4:1, putting the mixture into a tissue crushing barrel, adding collagenase after crushing, uniformly mixing, hatching at the temperature of 37 DEG C, filtering, adding a precipitator, sucking a supernatant fluid after settling, centrifuging, removing the supernatant fluid, adding concentrated cells into a liquid of diatrizoate sodium-ficoll 400#, then centrifuging, collecting 10-15 ml of intermediate cell layer, washing with the cell maintenance fluid, counting the collected cells, and providing the cells for clinical use when the cell survival ratio is more than or equal to 95 percent. The invention not only realizes the separation and the extraction of all stem cells from the placenta, umbilical cord or adipose tissue, but also realizes industrialized production, and enables doctors to conveniently, safely and canonically obtain the adult stem cells in clinic and use the adult stem cells for treating the diseases of patients as using medicaments, thereby solving the bottleneck problem of difficult obtainment of adult stem cells in clinic and popularizing a cell treatment technology.

A transport network includes a flexible topology for internally defining transport elements. The transport elements each include a port group having a plurality of geographically distributed ports from the transport network. Point-to-multipoint connectivity is defined between the ports in a port group. An identifier represents the port group as a single element to internal and / or external elements for protocol exchanges.

An adhesive patch is provided wherein the patch includes a porous backing having a front side and a back side. The patch also includes a therapeutic formulation located on the front side of the backing. The backing includes a flexible sheet of water insoluble porous material. The therapeutic formulation includes a combination of a antiviral agent useful for treating a viral infection in a mammal (e.g., human), a medicament that relieves topical discomfort, an adhesive, and a solvent. The solvent can preferably include a fragrance.

A double-layer shutter control method of a multi-sputtering system provided with three targets in a single chamber and a double-layer rotating shutter mechanism having shutter plates which independently rotate and have holes formed therein, comprising selecting a target by a combination of holes of a first shutter plate and a second shutter plate and uses the selected target for a pre-sputtering step and a main sputtering step with continuous discharge so as to deposit a film on a substrate, whereby it is possible to prevent cross-contamination between targets due to target substances etc. deposited on the shutter plates.