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2506results about How to "Avoid cross contamination" patented technology

Microfabricated crossflow devices and methods

A microfluidic device for analyzing and / or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are useful for sorting particles, e.g. virions. The invention is also useful for high throughput screening, e.g. combinatorial screening. The microfluidic device comprises a main channel and an inlet region in communication with the main channel at a droplet extrusion region. Droplets of solution containing the biological material are deposited into the main channel through the droplet extrusion region. A fluid different from and incompatible with the solution containing the biological material flows through the main channel so that the droplets containing the biological material do not diffuse or mix. Biological material within the droplets can be analyzed and / or sorted by detecting a predetermined characteristic of the biological sample in each droplet and sorting the droplet accordingly.
Owner:CALIFORNIA INST OF TECH

Compositions and methods for the treatment of disease

The present invention relates to pharmaceutical compositions for the treatment and / or prophylaxis of disease associated with fibrosis in a vertebrate, said composition comprising at least one activin antagonist, and optionally a pharmaceutically acceptable carrier, adjuvant and / or diluent. The invention also relates to methods of treatment of disease associated with fibrosis in a vertebrate, as well as methods for diagnosing such conditions, and kits therefor.
Owner:MONASH UNIV +1

Protective sheet loader

A protective sheet loader may comprise a first roller, a second roller, a sheet of material spanning between the first and second rollers, and a loading mechanism. A portion of the sheet of material may be loaded into the crimping chamber of an apparatus for reducing the size of a medical device. A medical device may be placed within the crimping chamber such that the sheet of material forms a barrier between the walls of the crimping chamber and the medical device and prevents cross-contamination between the medical device and the crimping device. After a crimping step is completed, the medical device and the contaminated portion of the sheet of material may be removed from the crimping chamber, and a clean portion of the sheet of material may be loaded into the crimping chamber.
Owner:BOSTON SCI SCIMED INC

Material removal and dispensing devices, systems, and methods

The present invention provides material removal heads and devices for noninvasively removing materials from the wells of multi-well plates. The material removal heads of the invention are structured to prevent cross-contamination among wells of multi-well plates as materials are removed from the plates. The invention also provides dispense heads and devices that include angled dispensers. Related systems, kits, and methods are additionally provided.
Owner:IRM

Cooler with multiple compartments

An insulated cooler with two (2) separate independent storage compartments and lids allowing for compartmentalized transportation and storage of items is herein disclosed. The separate compartments eliminate possible cross-contamination as well as provide different thermal conditioning of the contents. The compartments are completely independent of each other having an interior divider wall extending completely through the body of the cooler and continuing into a lid area, thereby sealing independent compartments. Additionally, each compartment is also provided with a draining means.
Owner:EVANS DEBORAH B

Butt joint type operation patient transfer trolley

The invention discloses a butt joint type operation patient transfer trolley and belongs to the technical field of medical apparatus. The butt joint type operation patient transfer trolley comprises a transverse moving bed and a transfer trolley. The transverse moving bed with a tiltable bed top is disposed on a transfer trolley plate of the transfer trolley and locked by a bed locking device. The transfer trolley comprises a transfer trolley body, a transfer trolley base and a lifting device. The transfer trolley body is supported on the transfer trolley base through the lifting device. The transverse moving bed mainly comprises a transverse moving bed frame, a bed board, an air cushion and rollers. Inflation of the air cushion enables the bed board to tilt. By the butt joint technology, an operation patient along with the moving bed is transferred from the transfer trolley outside an operating room to the transfer trolley in the operating room, cross infection is avoided, operating environments are kept clean, and operating safety is increased. By the moving bed with the tiltable bed top, the patient can be transferred from the operation patient transfer trolley to an operating table conveniently and time- and labor-savingly. The butt joint type operation patient transfer trolley is suitable for transferring seriously-injured patients from ambulances to operating rooms of hospitals.
Owner:HAINAN UNIVERSITY

Automated instrument for nucleic acid extraction and mass spectrum sample application

The invention discloses an automated instrument applied to nucleic acid extraction and continuous operation process of a mass spectrum sample application chip in biomass spectrometry analysis of a nucleic acid sample. The automated instrument comprises three main devices, namely, a nucleic acid extraction and purification device, a nucleic acid liquor relief distributing device and a mass spectrum chip sample application device, wherein nucleic acid in body fluid is extracted by using a magnetic bead method, a mechanical arm is utilized to complete a nucleic acid extraction action, the extracted nucleic acid is dispensed onto a sample board through a dispenser, a pipettor is used for transferring the sample board onto a chip sample application instrument, and the mass spectrum and relatedinformation of the nucleic acid are obtained through laser sampling of a mass spectrometer, so that the nucleic acid is analyzed rapidly, directly and continuously. The automated instrument is high-precision in controlling the volume of dispensed liquor, high-cleanliness in controlling the quality of the dispensed liquor and high-efficiency in meeting sample application requirements of large-batch samples; meanwhile, the samples are uniformly distributed under the control of a computer program, volume errors and possible foreign pollution caused by manual operation are avoided, and the speed and efficiency in sample application are increased at the same time.
Owner:BIOYONG TECH

Method for separating and extracting stem cells from placenta, umbilical cord or adipose tissue

The invention relates to a method for separating and extracting stem cells from a placenta, umbilical cord or adipose tissue, which comprises the following process steps: firstly mixing the placenta, umbilical cord or adipose tissue and a cell maintenance fluid according to the proportion by weight of 2.5-4:1, putting the mixture into a tissue crushing barrel, adding collagenase after crushing, uniformly mixing, hatching at the temperature of 37 DEG C, filtering, adding a precipitator, sucking a supernatant fluid after settling, centrifuging, removing the supernatant fluid, adding concentrated cells into a liquid of diatrizoate sodium-ficoll 400#, then centrifuging, collecting 10-15 ml of intermediate cell layer, washing with the cell maintenance fluid, counting the collected cells, and providing the cells for clinical use when the cell survival ratio is more than or equal to 95 percent. The invention not only realizes the separation and the extraction of all stem cells from the placenta, umbilical cord or adipose tissue, but also realizes industrialized production, and enables doctors to conveniently, safely and canonically obtain the adult stem cells in clinic and use the adult stem cells for treating the diseases of patients as using medicaments, thereby solving the bottleneck problem of difficult obtainment of adult stem cells in clinic and popularizing a cell treatment technology.
Owner:NINGXIA ZHONGLIANDA BIOPHYSICS
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