The invention provides a high-voltage switch cabinet capable of being automatically cooled and cleaned. The high-voltage switch cabinet comprises a cuboidal cabinet body which is composed of a left side plate, a right side plate, a top plate, a bottom plate, a back side plate and cabinet doors; the left side plate and the right side plate are each provided with a blind window, and the inner wall of the left side plate and the inner wall of the right side plate are provided with dust removing mechanisms at the blind windows; a left vertical plate and a right vertical plate are arranged between the top plate and the bottom plate, the left vertical plate is parallel to and adjacent to the left side plate, the right vertical plate is parallel to and adjacent to the right side plate, air suction holes are evenly formed in the left vertical plate and the right vertical plate, and the right side of the left vertical plate and the left side of the right vertical plate are provided with electric elements; an air volume rotating regulating mechanism is arranged between the center of the top plate and the center of the bottom plate. The high-voltage switch cabinet has the advantages of being simple in structure, easy to operate, good in heat dissipation effect, little in energy consumption, high in reliability and good in dust-proof effect, the electric elements in the cabinet body can keep the good working state temperature by regulating the air sucking volume, and therefore the service life of the electric elements is prolonged.