A presence / absence test for
Staphylococcus aureus (S. aureus) involves placing a
first generation test sample in a solution that will clot in the presence of S. aureus. The solution contains components that will selectively grow S. aureus and also contains
clotting factors that will react with S. aureus, if S. aureus is present in the sample, to clot the solution. Examples of specimen samples that can be tested include nasal swabs and
lesion swabs, among others. The test can also be modified to detect the presence or absence of methicillin resistant S. Aureus (MRSA). The addition of
micro particles having a size in the range of about 0.1 micron to about 1.0 mm provides localities where the
bacteria agglomerate, thereby significantly decreasing the
clotting time, and providing a significantly stronger clot. The
micro particles can be used in other
bacteria tests to accelerate the production of an end result. Such other tests can include a
vancomycin-resistant
enterococcus test; a Group B
Streptococcus test; a test for hemolytic E. coli; and a test for
Listeria monocytogenes, to name a few. These tests are all performed in a liquid broth-type
reagent mixture and do not necessarily involve clotting of the broth.