The invention relates to the technical field of medical instruments, in particular to a malignant pleuroperitoneal effusion perfusion treatment device. Comprising a moving assembly, a base, a filling module, a hose, a supporting frame, an adjusting cylinder, a driving assembly, a gear, a rack and a traction assembly, the adjusting cylinder is arranged on the supporting frame, the driving assembly is fixedly connected with the adjusting cylinder, the gear is fixedly connected with the driving assembly, and the traction assembly comprises a connecting block, a connecting ring, a traction rope and a sleeving ring; the connecting ring is fixedly connected with the connecting block, the sleeving ring is arranged on the outer side wall of the hose in a sleeving mode, one end of the traction rope is fixedly connected with the connecting ring, the other end of the traction rope is fixedly connected with the sleeving ring, the connecting ring and the sleeving ring are connected through the traction rope, the hose is restrained under the traction force of the traction rope, and restraining of the hose is achieved; the situation that in the treatment process of a patient, the shape of the hose is changed at will, treatment operation of medical staff is affected, and the treatment progress is affected is avoided.