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45 results about "Differential effects" patented technology

The differential effect of the two treatments is the effect of applying one treatment in lieu of the other. In randomised experiments, the differential effect is of no more or less interest than other treatment contrasts. Differential effects play a special role in certain observational studies in which treatments are not assigned...

Residual frequency effects compensation

A means is provided to estimate the amount of frequency deviation experienced in a precision resonator resulting from the effects of previous thermal history, acceleration, or aging by determining the differential effect of the perturbing condition on different resonant modes in the same resonator or on different resonators exposed to the same environment. The measurements may be made simultaneously, or sequentially against an independent frequency source. Residual frequency hysteresis effects may be determined in connection with an independent temperature sensor if the exact temperature in not known.
Owner:FRERKING MARVIN E

Gigahertz impulse gate-control low-pass filtering ultrared single-photon detector

InactiveCN101650228AWork fasterReduced afterpulse effectInstrumentsCapacitanceDifferential effects
The invention relates to the fields of quantum secret communication, weak ultrared detection, and the like, and provides an impulse gate-control low-pass filtering ultrared single-photon detector. Theimpulse gate-control low-pass filtering ultrared single-photon detector comprises an impulse gate-control power source, an In-Ga-As-In-P avalanche photodiode circuit, a DC voltage baising circuit, alow-pass filter, a high-speed wideband amplifier, a ultra-high-speed comparator and a counter, wherein gigahertz (GHz) impulse signals output by the impulse gate-control power source are used as gatecontrol signals of the In-Ga-As-In-P avalanche photodiode circuit, and spike noise signals caused by the junction capacitance differential effect of In-Ga-As-In-P avalanche photodiodes by the low-passfilter are used for filtering in a low-pass mode. The gigahertz impulse gate-control low-pass filtering ultrared single-photon detector solves the problem of spike noise interference in the prior art, increases the detection sensitivity of the avalanche signals and can be used for detecting GHz high-speed ultrared photon.
Owner:ANHUI QASKY QUANTUM SCI & TECH CO LTD

Conduction time generation circuit for power supply converter, and power supply converter

The invention discloses a conduction time generation circuit for a power supply converter, and a power supply converter. According to the invention, a band-pass filtering circuit is additionally arranged, DC components of second reference signals are equal to first reference signals, a differentiating circuit has a differential effect, can rapidly react to change of output voltages, timely performs feedback and adjustment, and the change trench of AC components of the second reference signals is opposite to the change trench of the output voltages. According to the invention, in case of abrupt change of the output voltages, the second reference signals can timely perform feedback and adjustment so as to reduce influences generated due to the abrupt change of the output voltages and enable the output voltages to be rapidly recovered to be constant.
Owner:SILERGY SEMICON TECH (HANGZHOU) CO LTD

Gigahertz sine-wave gate-control low-pass filtering ultrared single-photon detector

InactiveCN101650227AWork fasterReduced afterpulse effectInstrumentsDifferential effectsCapacitance
The invention relates to the fields of quantum secret communication, weak ultrared detection, and the like, and provides a ultrared single-photon detector. The ultrared single-photon detector comprises a sine-wave gate-control power source, an In-Ga-As-In-P avalanche photodiode circuit, a DC voltage baising circuit, a semiconductor temperature-control circuit, a low-pass filter, a high-speed wideband amplifier, a ultra-high-speed comparator and a counter, wherein sine waves which have the frequency of gigahertz (GHz) and are output by the sine-wave gate-control power source are used as gate control signals of the In-Ga-As-In-P avalanche photodiode circuit, and spike noise caused by junction capacitance differential effect for the low pass filter is used for filtering in a low-pass mode. The gigahertz sine-wave gate-control low-pass filtering ultrared single-photon detector solves the problem of spike noise interference in the prior art, increases the detection sensitivity of avalanchesignals and is used for detecting GHz high-speed ultrared photon.
Owner:UNIV OF SCI & TECH OF CHINA

Wheel-side differential lock axle

The invention relates to a wheel-side differential lock axle for an engineering vehicle and belongs to the technical field of manufacturing of engineering vehicle chassis type rear axle assemblies. The wheel-side differential lock axle comprises a rear axle housing assembly, a main reducer assembly, a hub brake drum assembly, a brake assembly and a half axle, wherein the main reducer assembly comprises a main reducer housing, a working cylinder assembly, a shifting fork shaft, a shifting fork, a fixed meshing sleeve, a slidable meshing sleeve, a half axle gear, a left differential carrier, a right differential carrier, a driven bevel gear, a cross axle, a planet gear, a drive bevel gear, a flange assembly and the like. The wheel-side differential lock axle has the advantages that when the wheels of the engineering vehicle traveling on a road surface with bad working conditions slip, the meshing sleeves of the differential lock structure allow the differential carriers and the half axle to be integrally connected so as to allow a differential mechanism to lose the differential effect temporarily, and the vehicle can travel normally; the wheel-side differential lock axle is high in bearing capacity, high in fatigue resistance, good in brake performance and the like, the passing capacity of the whole engineering vehicle is good, and the wheel-side differential lock axle is suitable for being used by various engineering vehicles in construction sites of various working conditions.
Owner:HUBEI AXLE

Structure-based modeling and target-selectivity prediction

The present invention provides, inter alia, methods, models, and systems for selecting an effector having specificity for a target molecule. The methods and systems of the present invention involve several steps, including compiling a database containing structural data for a library of molecules and a population of ligands and activity data, establishing structure-based equivalence of sequence elements in the library of molecules, determining likely spatial orientations of population ligands in library molecules, calculating interaction energies for each ligand-molecule pair, generating statistical models that are predictive of sequence elements likely to contribute to a differential effect of ligands on molecules, selecting an effector that is likely to have a desired specificity for the target molecule, experimentally determining activity data for effector-library molecule pairs, and at least once repeating the steps listed above wherein the effector is a member of the population of ligands.
Owner:EPIGENETX

Bionic moisture-permeable and sweat-discharge yarn and preparation device and method thereof

The invention discloses a bionic moisture-permeable and sweat-discharge yarn and a preparation device and method thereof. The moisture-permeable and sweat-discharge yarn is internally provided with a tree-shaped cross network channel for simulating an internal water conveying channel of a plant. The preparation device comprises an insulating conical cover, and air nozzles are symmetrically arranged on the two sides of the inner wall of the insulating conical cover; a metal rod with a metal circular ring at one end is arranged on the lower portion of each air nozzle, and an electrostatic spinning sprayer is arranged below each metal circular ring. The preparation method comprises the steps that yarns of core layer fibers penetrate through the center from the bottom of the insulating conical cover to the top of the insulating conical cover, and air in the insulating conical cover spirally moves along the inner wall at a high speed to drive electrostatic spinning nanofibers to move spirally, so that the yarns are wrapped with the nanofibers, and the prepared moisture-permeable and sweat-discharge yarns are exposed from the top of the insulating conical cover. The water guiding channel in the plant is simulated, the pressure difference formed due to different sizes of the gaps of the surface and inner layers is used for generating the differential effect, the moisture guiding capability is obviously enhanced, and the one-way moisture guiding capacity is achieved.
Owner:DONGHUA UNIV

Differential electric motor

The invention discloses a differential electric motor. A motor stator used for being connected with an external power source to generate an electromagnetic field is fixedly arranged on a middle section of a body, and motor rotors driven to rotate by the electromagnetic field of the motor stator are arranged on two sides of the body respectively through a shaft. The whole differential electric motor can be installed on a vehicle body of an electric vehicle through the body, the motor stator is connected with a power supply system of the electric vehicle, and the two motor rotors are connected with transmission wheels on the left and the right of the electric vehicle respectively; when the vehicle body travels on a curved road or turns, due to the fact that the two motor rotors connected with the transmission wheels rotate relative to the motor stator respectively, the friction resistance of a road surface can be automatically reflected, an asynchronous differential effect is generated naturally, the vehicle body has the good steering performance, and improper abrasion of the transmission wheels can be avoided.
Owner:HONGYU MOBILITY CORP +1

Methods of selectively treating diseases with specific glycosaminoglycan polymers

The present invention demonstrates that defined, specific GAG molecules have discerned differential effects, and that different types of cancers are prevented from proliferating and / or killed by oligosaccharides of different sizes; one size sugar does not treat all cancers effectively. Likewise, certain size GAGs have more potent angiogenic properties; thus, mixtures of different sizes of GAG molecules are not optimal. Therefore, the present invention is directed to methods of “personalized medicine”, in which customized defined, specific GAG molecules are administered to a patient, wherein the defined, specific GAG molecules are chosen based on the specific ailment from which the patient is suffering and / or the response of in vitro testing of the ability of the defined, specific GAG molecules to treat, inhibit and / or prevent the ailment in a sample from the patient.
Owner:RGT UNIV OF OKLAHOMA THE BOARD OF +1

Optimized cardiac contraction through differential phosphorylation of myosin

The present disclosure provides a cDNA, protein sequence, and genomic structure of the human cardiac isoform of myosin light chain kinase (cMLCK), and describes mutations in the cMLCK gene that are associated with cardiac dysfunction. Methods are provided for identifying individuals who can harbor mutations in the cMLCK gene, or carry alleles that can predisposed them to cardiac dysfunction. Disclosed also is a significant role for cMLCK in modulating cardiac contractility. The cMLCK protein is shown herein to reduce the amplitude of stretch activation and increase the tension production, a property of muscle which has heretofore had an unknown role in cardiac contraction. Moreover, the cMLCK protein is shown to be regionally distributed in the heart, thereby having differential effects on contractility and stretch activation. Methods herein are provided to exploit this effect of cMLCK, to treat individuals who have or are prone to cardiac dysfunction. In addition, methods are provided to identify agents that modulate cMLCK activity, thereby having potential therapeutic importance in the treatment of cardiac dysfunction.
Owner:UNITED STATES OF AMERICA

Drug for treating hepatocellular carcinoma and application of glucagon-like peptide-1 receptor stimulant and/or dipeptidyl peptidase 4 inhibitor

The invention provides a drug for treating hepatocellular carcinoma. The drug comprises a glucagon-like peptide-1 receptor stimulant and / or a dipeptidyl peptidase 4 inhibitor. The invention further provides application of the glucagon-like peptide-1 receptor stimulant and / or dipeptidyl peptidase 4 inhibitor to preparation of a drug for preventing or treating hepatocellular carcinoma, to preparation of a drug for liver function recovery after liver transplantation, and to preparation of a drug for preventing liver cancer relapse after liver transplantation. The glucagon-like peptide-1 receptor stimulant and / or dipeptidyl peptidase 4 inhibitor generates a differential effect in a tissue specificity way, so as to inhibit cancer cell proliferation and promote cancer cell apoptosis, meanwhile, liver cells are protected against apoptosis, so that obesity-dependent liver cancer or non-dependent liver cancer can be treated or weakened.
Owner:SUN YAT SEN UNIV

Mini-tiller with differential and power switching functions

The invention provides a mini-tiller with differential and power switching functions. The mini-tiller comprises a gearbox and a transmission shaft, wherein a gear shifting gear is arranged on the transmission shaft, a gear shifting pulling mechanism is arranged on the gearbox, a power switching mechanism is also arranged on the gearbox, and comprises a second spline sleeve and a power switching pulling mechanism, the second spline sleeve is arranged on the front end of the transmission shaft in a sleeving manner, the power switching pulling mechanism is arranged on the gearbox, a position limiting element is arranged on the power switching pulling mechanism, and a stop element is arranged on the gear shifting pulling mechanism. The mini-tiller has the advantages that the switching-in and switching-off operations of the power of the work mechanism can be realized through pulling the second spline sleeve to realize the combination and the separation with a power input shaft of a work mechanism, through the matching of the position limiting element and the stop element, the pulling to a retreating gear in the work process is avoided, people injury due to backwards retreating mini-tiller in the work process is prevented, the differential effect can be realized, further, the steering in the walking process is convenient to realize, the operation is convenient, and meanwhile, the differential lock function is realized.
Owner:CHONGQING HWASDAN MACHINERY MFG

Differential bevel gear driving type multi-wheel carrier

InactiveCN104948709AEfficient and convenient up and down stairsAvoid overall overturningDifferential gearingsGearing detailsDifferential effectsDrive shaft
The invention relates to a wheel of a ladder-climbing vehicle. The structure is as follows: a transmission shaft is fixedly connected with a large bevel gear at one side, the large bevel gear at one side is engaged with a small bevel gear, the small bevel gear can rotate on a cross axle, the cross axle and a differential shell are fixedly connected with a multi-wheel carrier, a large bevel gear at the other side and a small wheel maintain a transmission relation via a transmission mechanism, and a rotating shaft of the transmission mechanism is fixed on the multi-wheel carrier. The functions are as follows: during movement on the flat ground, the multi-wheel carrier does not overturn, the differential shell and the cross axle fixedly connected with the multi-wheel carrier do not rotate. The transmission shaft drives the large bevel gear fixedly connected with the transmission shaft to rotate, the large bevel gear drives the small bevel gear to rotate, the rotation of the small bevel gear drives the large bevel gear at the other side and a sun gear to rotate, and the transmission device enables the small wheel to rotate. During ladder climbing up and down, the transmission shaft drives the large bevel gear fixedly connected with the transmission shaft to rotate, the small bevel gear performs revolution and rotation, the cross axle performs revolution, the multi-wheel carrier performs revolution, and the large bevel gear at the other side and the sun gear rotate so that the small wheel rotates. The rotation speed of the small wheel and the revolution speed of the wheel carrier are automatically adjusted via the differential effect.
Owner:李军委

Rail damage testing device and method based on three-way electromagnetism differential sensor

The invention belongs to the field of electromagnetism flaw detection applications in electromagnetism detecting techniques, relates to a rail damage testing device based on a three-way electromagnetism differential sensor, which comprises the three-way electromagnetism differential sensor, a signal processing circuit, an FPGA (Field Programmable Gate Array) control chip, and an upper computer, wherein the three-way electromagnetism differential sensor comprises a sensor bracket; three bifurcations in three directions are arranged at the front part of the bracket; each bifurcation is provided with a probe composed of a testing coil and an exciting coil, and the exciting coil is wound at the middle section of the bifurcation; the testing coil is coiled by a conducting wire and is divided into two parts with same winding turns and opposite coiling directions according to different coiling directions and positions so as to produce differential effects; and three probes are used for detecting whether a rail web, a rail jaw, and a rail chair are damaged respectively. Meanwhile, through the adoption of the device, the invention provides a rail damage testing method. The device has the advantages of simplicity, quickness, and lower cost.
Owner:常州兆能电子科技有限公司

Off-location technology based REBCO superconducting film growing continuous device

The invention provides an off-location technology based REBCO superconducting film growing continuous device. A reel-to-reel multi-pass reciprocating film coating unit deposits a target material ontoa base band to form a metal film through magnetron sputtering. The base band passes through two slits of a vacuum trap successively and gets into three quartz tubes to be subjected to heat treatment,so that the metal film on the base band absorbs oxygen to be converted into a superconducting phase superconducting film. Through the off-location technology based REBCO superconducting film growing continuous device, the technical defects are overcome; the off-location technology based REBCO superconducting film growing continuous device conducts deposition coating through the magnetron sputtering off-location technology; and the vacuum trap is introduced to serve as a transition device to enable the film coating and heat treatment processes to change into a continuous system and meanwhile can ensure that the film coating and heat treatment processes are non-interfering, that is, film coating and superconducting phase implementation can be carried out in the two different and continuous processes. The off-location technology based REBCO superconducting film growing continuous device can achieve the vacuum differential effect through a set of quartz tubes of different thicknesses and conducts heat treatment on the film under different oxygen partial pressures to realize conversion of the film from the metal film to the superconducting film
Owner:SHANGHAI SUPERCONDUCTOR TECH CO LTD

Micro-drive system and clamping system comprising same

The invention discloses a micro-drive system and a clamping system comprising the micro-drive system. The micro-drive system is based on a shape memory effect and is driven by two shape memory alloy rods which are mutually perpendicular, a first shape memory alloy rod is electrified and contracts to push a drive piston to move forwards through a transmission rod assembly, a second shape memory alloy rod is electrified and contracts to drive the drive piston to reset, and at the same time, the two shape memory alloy rods can respectively serve as a drawing power source of each other to produce plastic deformation. The clamping system comprises the micro-drive system and an internal reflux area differential stroke amplifying device, due to the fact that a reflux hole is formed in an output piston, the differential effect is achieved, the effective acting area of the output piston is made to be only the cross sectional area of a piston rod, and therefore the amplification coefficient is improved on the basis of reduction of the size of the stroke amplifying device. Compared with a traditional drive clamping device, the clamping system is small in size, simple in structure, good in controllability, fewer in energy conversion steps, high in utilization rate of energy, free of pollution, and capable of protecting environment.
Owner:SUZHOU UNIV

Differential linkage device of washing machine

The invention relates to a differential linkage device of a washing machine. The differential linkage device of the washing machine is provided with a drive shaft and a drive shaft sleeve. The drive shaft is rotationally arranged in the drive shaft sleeve and a clutch linkage mechanism is arranged between the drive shaft and the drive shaft sleeve; the clutch linkage mechanism is provided with an electromagnetic clutch assembly and a cross sliding block differential assembly. According to the differential linkage device of the washing machine, an electromagnetic clutch and a cross sliding block differential linkage mechanism are adopted, so that the differential linkage mechanism of the washing machine is greatly simplified and the differential effect is guaranteed when the washing machine is under the washing and dewatering conditions. The differential linkage device of the washing machine is simple in structure and small in size, under the washing condition, the rotation speed of an inner barrel is relatively lower than that of an impeller, and therefore winding of clothes and abrasion caused by the inner barrel to the clothes are reduced.
Owner:CHANGZHOU XINYA ELECTROMOTOR

Differential effects of drugs on transport in a multi-layer 3D spheroid model

Drugs are screened for affects on inhibiting efflux pumps and blocking gap junction communication in tumors by culturing cells to thereby form self-assembled spheroids and incubating the spheroids. Uptake of a substrate of the efflux pump and distribution of a substrate for the efflux pump within the spheroids is imaged to thereby select drugs that inhibit the efflux pump or do not block gap junction communication. Selected drugs can then be employed to treat a tumor.
Owner:BROWN UNIVERSITY

Vortex spinning sportswear fabric

The invention discloses a vortex spinning sportswear fabric which comprises a fabric body in a double-faced fisheye texture structure. Inner threads of the fabric body are high in fineness and form athick capillary structure, and outer threads of the fabric body are low in fineness and form a thin capillary structure. The outer threads are made of flax fiber and wool fiber blended vortex spun yarns, and the inner threads are made of hollow core spun yarns. The vortex spinning sportswear fabric is great in moisture absorption and sweat releasing performance and comfortable to wear, and elongated meshes are formed in the back surface of the fabric; since the inner threads are made of the hollow core spun yarns, high fluffiness, great heat preservation effects and fabric front smoothness arerealized; since the outer threads are made of the flax fiber and wool fiber blended vortex spun yarns, great heat conducting effects are achieved, quick heat radiation is realized, and sweat releaseis facilitated due to internal and external differential effects.
Owner:SUZHOU CITY XINGJINGZE FIBER TECH CO LTD

Manipulator

The invention discloses a manipulator which comprises a finger root, a finger pulp, a finger tip and a power mechanism, and further comprises a differential mechanism, wherein the finger pulp is rotatably connected onto the finger root; the power mechanism is rotatably connected onto the finger pulp; the differential mechanism is connected with the power mechanism, so that when the rotation of thefinger pulp is limited by a grabbing object, the finger tip is driven by the power mechanism to rotate relative to the finger pulp and towards the grabbing object; and when the finger pulp is not limited by the grabbing object, the finger pulp is driven by the power mechanism to rotate. The manipulator disclosed by the invention has the advantages that by utilization of the differential mechanism, the differential effect is generated between the finger pulp and the finger tip, so that the action of a real hand to grab an object can be better simulated; during the grabbing action, such a grabbing way that a finger pulp and a finger tip of a conventional manipulator simultaneously rotate towards the grabbing object is adopted; and accordingly, compared with the conventional manipulator, themanipulator disclosed by the invention further fits human engineering.
Owner:LENOVO (BEIJING) LTD

Differential sampling temperature control method of heating system

The invention provides a differential sampling temperature control method of a heating system. The differential sampling temperature control method comprises the following steps: firstly, acquiring the control target temperature, and sending the control target temperature to a controller; then, opening a temperature caching queue in the storage space of the controller, placing the temperature in each sampling at the tail end of the temperature caching queue, and updating the temperature caching queue in a first-in and first-out manner; then, subtracting the temperature in the temperature caching queue from the target temperature to obtain a temperature feedback error, which is used as an error input variable of a PID controller; using the temperature change speed before and after samplingas an error change rate input variable of the PID controller; controlling the temperature of the heating system through the PID controller. In allusion to a temperature control system having a slow changing process, different sampling frequencies are adopted for the error and the error change rate in a feedback link and the sampling period of the error change rate is set to be several times of theerror sampling period, so that the differential effect of a PID algorithm is enhanced and actuator oscillation of the temperature control system is suppressed.
Owner:DONGHUA UNIV

Running brake system and vehicle

The invention provides a running brake system and a vehicle. A rear brake loop in the running brake system comprises a second cavity of a mater pump assembly, a central brake assembly, a left differential lock assembly and a right differential lock assembly. When a pedal plate of a brake pedal plate assembly is treaded, the left differential lock assembly and the right differential lock assembly enable a rear axle differential mechanism to lose the differential effect under the hydraulic effect. The running brake system solves the problems that an existing running brake system is poor in heat-fading resistance and reliability, the phenomenon that when the vehicle is braked, due to affected by poor part consistency, large differences exist in brake torque of a left wheel and a right wheel of a rear axle is avoided, and the brake stability is improved.
Owner:BEIQI FOTON MOTOR CO LTD

Temperature regulation method and device

The invention discloses a method for temperature regulation, which includes: measuring the current temperature value and obtaining the deviation e according to the current temperature value; when the second deviation threshold<|e|≤the first deviation threshold, adjusting P, I and D, increasing The proportional action and integral action in the control weaken the differential action; when 0≤|e|≤the second deviation threshold, adjust P, I and D to weaken the proportional action, integral action and differential action in the control; according to the third deviation Threshold A and deviation e, adjust the integral action intensity factor; according to the adjusted P, I, D and integral action intensity factor, obtain the increment of the control amount, and adjust the temperature according to the increment of the control amount. The invention also discloses a temperature regulating device. The invention can effectively reduce the phenomenon of overshoot and oscillation in the process of temperature control.
Owner:北京英华达电力电子工程科技有限公司

A kind of service brake system and vehicle

A running brake system and a vehicle. A rear brake loop in the running brake system comprises a left differential lock assembly (22) and a right differential lock assembly (23). When a pedal of a brake pedal assembly (14) is treaded, the rear brake loop is used for braking an input shaft of a rear axle differential, and the left differential lock assembly (22) and the right differential lock assembly (23) make the rear axle differential lose the differential effect under the hydraulic effect. When the running brake system needs to carry out braking, the rear axle can be braked as a whole by means of the rear axle differential, therefore the phenomenon is avoided that when an automobile is braked, large difference exists in brake torque of a left wheel and brake torque of a right wheel of a rear axle due to influence of poor component consistency, and accordingly, the brake stability is improved, thereby solving the problems that an existing running brake system is poor in heat-fading resistance and reliability.
Owner:BEIQI FOTON MOTOR CO LTD

Tiller with differential speed and power switching function

The invention provides a mini-tiller with differential and power switching functions. The mini-tiller comprises a gearbox and a transmission shaft, wherein a gear shifting gear is arranged on the transmission shaft, a gear shifting pulling mechanism is arranged on the gearbox, a power switching mechanism is also arranged on the gearbox, and comprises a second spline sleeve and a power switching pulling mechanism, the second spline sleeve is arranged on the front end of the transmission shaft in a sleeving manner, the power switching pulling mechanism is arranged on the gearbox, a position limiting element is arranged on the power switching pulling mechanism, and a stop element is arranged on the gear shifting pulling mechanism. The mini-tiller has the advantages that the switching-in and switching-off operations of the power of the work mechanism can be realized through pulling the second spline sleeve to realize the combination and the separation with a power input shaft of a work mechanism, through the matching of the position limiting element and the stop element, the pulling to a retreating gear in the work process is avoided, people injury due to backwards retreating mini-tiller in the work process is prevented, the differential effect can be realized, further, the steering in the walking process is convenient to realize, the operation is convenient, and meanwhile, the differential lock function is realized.
Owner:CHONGQING HWASDAN MACHINERY MFG
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