30 results about "Coronary plaque" patented technology

Systems, methods and apparatus are provided through which coronary plaque is classified in an image and visually displayed using an iterative adaptive process, such as an expectation maximization process.

Systems and methods are disclosed for predicting coronary plaque vulnerability, using a computer system. One method includes acquiring anatomical image data of at least part of the patient vascular system; performing, using a processor, one or more image characteristics analysis, geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis on the anatomical image data; predicting, using the processor, a coronary plaque vulnerability present in the patient's vascular system, wherein predicting the coronary plaque vulnerability includes calculating an adverse plaque characteristic based on results of the one or more of image characteristics analysis, geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis of the anatomical image data; and reporting, using the processor, the calculated adverse plaque characteristic.

In the methods of the invention, an agent that increases phagocytosis and/or efferocytosis of cellular components of coronary plaque is administered to the subject in a dose and for a period of time effective to stabilize, prevent or reduce aneurysm disease in the individual.

The invention discloses a multi-frequency three-dimensional coronary artery plaque detecting method.The multi-frequency three-dimensional coronary artery plaque detecting method comprises the steps that S1, two current emitting electrodes and two voltage detecting electrodes are arranged on an impedance catheter, and a same-current multi-frequency scanning method is adopted to measure the cross section of the inner cavity of a blood vessel to be detected; S2, voltage values of the required measurement positions in the blood vessel to be detected where the impedance catheter is located are respectively acquired at the same current and in a sweep frequency state; S3, the impedance catheter is driven to perform uniform motion, and voltage values of the impedance catheter in the motion process are acquired at the same current in multiple frequency period switching states; S4, the voltage values obtained in the multiple frequency period switching states, the cross sections of the positions of the blood vessel to be detected and conductance parameters corresponding to plaque loads are acquired; S5, a numerical calculation and numerical optimization combination method is adopted to calculate three-dimensional spatial distribution of the plaque parameters of the positions of the blood vessel to be detected, and the three-dimensional spatial distribution of the plaques in the blood vessel wall is further determined.The multi-frequency three-dimensional coronary artery plaque detecting method is more accurate than a traditional single-frequency method.

The invention belongs to the field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating coronary heart disease as well as a preparation method and application thereof. The traditional Chinese medicine composition for treating the coronary heart disease comprises the following raw materials of radix astragali, teasel, rhizoma cyperi, radix curcumae, rhizome ligustici wallichii, fructus trichosanthis, pericarpium citri reticulatae, ginger processed pinellia, poria cocos, bulbus fritillariae thunbergii, loofah sponge, caulis lonicerae, cortex cinnamomi and unprocessed radix glycyrrhizae. The traditional Chinese medicine composition provided by the invention is accurate in syndrome differentiation and focuses on pathogenesis, and a patient is stable in illness state after being treated with traditional Chinese medicine or combination of traditional Chinese medicine and western medicine; the technical effects of stabilizing coronary artery lesions, controlling blood fat, blood pressure and blood sugar stably and even reducing blood fat, blood pressure and blood sugar can be effectively achieved; the traditional Chinese medicine composition assists in controlling cardiovascular risk factors and stabilizing coronary plaques, and has a treatment effect of reversing the plaques after being taken for a long time; and the symptoms of chest distress and breath shortness are relieved.

The present disclosure is directed to compounds, diagnostic agents, and related methods. In some cases, methods for treating patients are provided. More specifically, the disclosure provides compounds, diagnostic agents, and kits for detecting and/or imaging and/or monitoring elastin rich tissues. In addition, the disclosure provides methods of detecting and/or imaging and/or monitoring the presence of coronary plaque, carotid plaque, iliac/femoral plaque, aortic plaque, renal artery plaque, plaque of any arterial vessel, aneurism, vasculitis, other diseases of the arterial wall, and/or damage or structural changes in ligaments, uterus, lungs or skin, as indicated by changes in total vessel wall area, internal lumen size, and exterior arterial perimeter.

The invention discloses a nano magnetic material for treating atherosclerosis, and a preparation method of the nano magnetic material. The preparation method comprises the following steps: preparing superparamagnetic nano Fe3O4 by utilizing a biomass material, wherein the surface is modified by ICG and polyethylene glycol; and injecting the prepared nano magnetic material into a human body, aiming, accumulating in lipid-rich coronary plaques, and irradiating local and far-end plaques with 808 nm laser to dissolve lipid. According to the invention, the nano magnetic material is used for fluorescence and magnetic resonance bimodal imaging diagnosis and near-infrared photothermal treatment of atherosclerosis; and the nano magnetic material and the preparation method thereof provided by the invention have a good application prospect, and the lipid is dissolved by using near-infrared heat treatment, so that the formation of the lipid is reversed, and the effect of treating atherosclerosis is good.

The invention provides a manufacturing method of a PVDF (Polyvinylidene Fluoride) micro-force sensor and an application method of the PVDF micro-force sensor in a surgical instrument, which are used for preparing a sensor capable of detecting stress data of a cardiovascular intervention surgical instrument in a blood vessel, and the micro-force sensor is of an elastic sandwich structure packaged by a waterproof and insulating protective film, comprises a piezoelectric film serving as a middle layer of the elastic sandwich structure, and further comprises two electrodes connected with the top face and the bottom face of the piezoelectric film respectively. The elastic sandwich structure is embedded in a mounting groove of the surgical instrument, the bottom surface or the top surface of the elastic sandwich structure is located on the outer surface of the surgical instrument, and when stress of the surgical instrument in a blood vessel is conducted to the micro-force sensor, a piezoelectric film of the micro-force sensor generates a detection electric signal; and according to the invention, the stress of a surgical instrument in a blood vessel can be measured with high sensitivity in real time, and the micro grinding force measuring device can be used for measuring the micro grinding force of collision between a rotary grinding head and a calcified tissue or a cardiovascular wall in a coronary artery plaque rotary grinding operation, so that the safety of removing the calcified tissue is improved.