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Simplified calculation method based on coronary artery multimode image crack formation and expansion and plaque fracture risk quantification evaluation system

A technology that simplifies the calculation and evaluation system. It is applied in the medical field and can solve the problem that it is not suitable for coronary plaque risk assessment.

Active Publication Date: 2021-07-30
THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the variability of coronary artery morphology over time during the cardiac cycle, this method is not well suited for the risk assessment of coronary plaques.
[0005] In conclusion, although the above-mentioned system software and patent documents obtain plaque stability assessment methods from different image sources and corresponding calculation methods, a single image source cannot fully present the tearing cracks in the superficial wall of lesioned coronary plaques penetrating the fibrous cap. plaque rupture process

Method used

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  • Simplified calculation method based on coronary artery multimode image crack formation and expansion and plaque fracture risk quantification evaluation system
  • Simplified calculation method based on coronary artery multimode image crack formation and expansion and plaque fracture risk quantification evaluation system
  • Simplified calculation method based on coronary artery multimode image crack formation and expansion and plaque fracture risk quantification evaluation system

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Embodiment 1

[0037] The present invention provides a simplified calculation method for the risk quantification index of crack formation and expansion in the process of individualized plaque rupture of patients based on coronary multimodal images. The following uses a specific example to use coronary angiography and optical coherence tomography as coronary artery angiography and optical coherence tomography respectively. The source of the multi-mode image is described in detail for the calculation method of the present invention. Those skilled in the art should understand that in this embodiment, the coronary artery image of a diseased vessel with a specific degree of stenosis and the OCT image data of a specific plaque component are used as an example, and this specific coronary artery disease and plaque type should not be used as an example. Or the corresponding image modality is understood as limiting the protection scope of the present invention.

[0038] In a specific embodiment of the...

Embodiment 2

[0072] In this specific embodiment, the present invention also provides a simplified calculation method based on coronary multimodal image crack formation and propagation and an evaluation system for plaque rupture risk quantification (such as figure 1 shown), the system includes:

[0073] The image input module is mainly used for the input of coronary multimodal images, including coronary angiography and coronary intraluminal images (optical coherence tomography, intravascular ultrasound imaging, etc.);

[0074] The image processing module is mainly used for key frame image screening, image enhancement, contour segmentation, plaque component identification, grid generation, and spatial position correspondence between multi-mode images of vessels of interest;

[0075] The quantification module of coronary plaque is mainly used for the description of anatomical indicators, including the diameter stenosis rate based on angiography, the minimum lumen diameter area, etc.; and the ...

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Abstract

The invention discloses a simplified calculation method based on coronary artery multimode image crack formation and expansion and a plaque fracture risk quantification evaluation system, and the method comprises the steps: obtaining multimode images, such as coronary artery angiography images and intracavity images (such as optical coherence tomography), through an image input module; respectively segmenting and registering interested blood vessels or plaques on different images by adopting an image processing technology, and quantitatively obtaining anatomical indexes of lesion coronary plaques; and further calculating the distribution of the dynamic indexes of the superficial wall based on time sequence coronary angiography and determining a relatively high-risk position along the longitudinal direction of the blood vessel so as to obtain a fatigue risk coefficient formed by the local crack of the superficial wall. According to the method, the anatomical indexes of the coronary artery multi-modal image are combined, and the quantitative assessment of the crack formation based on the superficial surface of the coronary artery and the plaque crack propagation risk based on the cross section image are further added, so that the plaque fracture process is assessed more completely and comprehensively.

Description

technical field [0001] The invention relates to a simplified calculation method and system for plaque rupture risk based on coronary images, and belongs to the field of medical technology. Background technique [0002] Plaque rupture secondary to occlusive thrombosis is the main pathogenesis of acute coronary syndrome. Quantitative assessment of the risk of plaque rupture will help clinicians formulate individualized prevention and treatment strategies to improve the long-term prognosis of patients with coronary heart disease. At present, the evaluation methods for identifying vulnerable plaques are mainly divided into two categories, namely, the evaluation of anatomical quantification indicators based on imaging, and the functional evaluation based on imaging. The first category of evaluation methods includes the SNYTAX score of quantifying coronary anatomy by angiography, and the diagnosis of thin-cap fibroma vulnerable plaque based on intraluminal imaging, etc., but the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06T7/11G06T7/136G06T7/33G06T7/62G16H50/30A61B5/00
CPCG06T7/0012G06T7/11G06T7/136G06T7/62G06T7/33G16H50/30A61B5/7275G06T2207/10101G06T2207/30101G06T2207/10028G06T2207/20081
Inventor 吴信雷卢孔场陈徐亮褚茂平
Owner THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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