34 results about "Cholinergic urticaria" patented technology

The invention provides a single nucleotide polymorphism site of ORAI1 genes of chronic urticaria susceptible patients and a detection agent thereof, and particularly provides a single nucleotide polymorphism site of rs3741595C / T, rs3741596A / G, rs12313273T / C and rs12320930G / T of ORAI1 genes, and the single nucleotide polymorphism site is adopted to detect chronic urticaria and to serve as the drug target for treating chronic urticaria patients. Drugs are applied on this basis, so the efficiency of disease treatment is improved and the living quality of the patients is improved. In addition, the morbidity can be predicted.

The invention discloses a traditional Chinese medicine composition for treating cholinergic urticaria. The traditional Chinese medicine composition is characterized by being prepared from the following components in parts by weight: 5 to 12 parts of schizonepeta, 5 to 12 parts of radix saposhnikoviae, 3 to 10 parts of periostracum cicada, 5 to 12 parts of cortex phellodendri, 5 to 15 parts of fructus forsythia, 10 to 40 parts of plaster stone, 5 to 15 parts of radix sophorae flavescentis, 5 to 15 parts of cortex dictamni, 3 to 10 parts of rhizoma cimicifugae, 5 to 12 parts of scutellaria baicalensis, 5 to 20 parts of radix rehmanniae, 5 to 15 parts of cortex moutan, and 3 to 8 parts of liquorice; and the components above can be prepared into any one of the forms of decoction, granules, pills or capsules by the general method of a traditional Chinese medicine preparation. The traditional Chinese medicine composition focuses on the optimization of effects of the components on clearing heat and removing toxicity, and dispelling wind and arresting itching, so as to specially treat adverse clinical symptoms of cholinergic urticaria; and with the coordinative action of all the components, the traditional Chinese medicine has the effects of accelerating the adequate eruption of cholinergic urticaria, dispersing and promoting eruption, eliminating wind and relieving convulsion, clearing away heat and drying dampness, nourishing Yin and engendering liquid, balancing internal environment, and particularly reducing hazardous substances in blood, so as to remove toxin from blood to the body surface along with sweat, and as a result, the cholinergic urticaria can be treated completely.