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65results about How to "The production process is complicated" patented technology

Nano Anticancer Micelles of Vinca Alkaloids Entrapped in Polyethylene Glycolylated Phospholipids

The present invention provides a nano-micellar preparation containing vinca alkaloids antitumor agent for intravenous injection, which cincludes a therapeutically effective amount of vinca alkaloids antitumor agent (vinblastine, vincristine, vindesine and vinorelbine), a phosphatide derivatized with polyethylene glycol, together with pharmaceutically acceptable adjuvants. The preparation is prepared by encapsulating the medicament with a nano-micelle to obtain the nano-micellar preparation containing vinca alkaloids antitumor agent for injection. The vinca alkaloids antitumor agent and the phosphatide derivatized with polyethylene glycol form a nano-micelle with a highly uniform particle size. In the micelle, the hydrophobic core of encapsulated medicament is surrounded by polyethylene glycol molecules to form a hydrophilic protective layer, so that the medicament is prevented from contacting with the enzymes and other protein molecules in blood and being recognized and phagocytozed by reticuloendothelial system in body, and the circulation time in vivo of the micelle is prolonged.
Owner:BEIJING DIACRID MEDICAL TECH

Production method of pattern in magnetic pigment fragment-containing coating layer and production device thereof

The invention relates to a device for producing a pattern in a magnetic pigment fragment-containing coating layer, which comprises two magnetic field generators, two solidified light sources, a light barrier, a baffle plate and a base material transmitter, wherein the base material transmitter comprises two wheel shafts arranged at two ends, and a feed belt which takes the two wheel shafts as shaft drive, one magnetic field generator, one solidified light source, the other magnetic field generator and the other solidified light source are sequentially arranged along with the direction from one wheel shaft to the other wheel shaft, and the surface of the feed belt is provided with a base material which is coated or printed with the magnetic pigment fragment-containing magnetic ink coating layer. The visually-changed safe pattern disclosed by the invention belongs to a first-line and second-line anti-counterfeiting synthesis technique, the true and false can be visually identified without any tools, and the magnetism of the pattern can be detected by magnetism detecting equipment as well; and the anti-counterfeiting ink which symmetrically changes by means of light and shade (color) along with the change of the visual angle is high in preparation difficulty, the effect is very hard to imitate, and the fidelity effect is extremely high.
Owner:甄健

Method and device for preparing anti-counterfeiting pattern capable of symmetrically changing with visual angles

ActiveCN102173247AClear boundariesThe preparation process is complexPattern printingPhysicsLight source
The invention relates to a method and a device for preparing an anti-counterfeiting pattern capable of symmetrically changing in brightness or colors with visual angles. The preparation device comprises a first magnetic field generation device, a second magnetic field generation device, a first curing light source, a second curing light source, a blocking grid plate and a base material conveying device. The anti-counterfeiting pattern prepared by the preparation method can change symmetrically by the methods of magnetic field induction, semi-blocking curing, secondary magnetic field induction and secondary curing, boundaries of all regions are clear and obvious, and fine stripes and the pattern can be realized; the preparation process can be kept continuous without interruption; and one magnetic field and one blocking curing are used as one unit, a plurality of units can generate a plurality of regions with the changes in the brightness or the colors, the preparation process is more complex, and the anti-counterfeiting function is higher.
Owner:甄健

Electronic paper device

The invention discloses an electronic paper device. The electronic paper device comprises a lower baseplate, an electrophoretic display medium layer and an upper baseplate, wherein the electrophoretic display medium layer is arranged between the upper baseplate and the lower baseplate, a plurality of parallel line electrodes are arranged on the surface adjacent to the electrophoretic display medium layer on the lower baseplate, a plurality of parallel column electrodes are arranged on the surface adjacent to the electrophoretic display medium layer on the upper baseplate, the line electrodes and the column electrodes are orthogonal mutually, the electronic paper device is divided into a plurality of pixel units through overlapped regions of the line electrodes and the column electrodes, and the optical state of the electrophoretic display medium layer is driven to change by forming an electric potential difference between the line electrodes and the column electrodes. By etching or printing a plurality of parallel strip-shaped electrodes on the surfaces of the upper baseplate and the lower baseplate for substituting TFT (thin-film transistor) pixel electrodes, the electronic paper device can be used for manufacturing a light and thin type electronic paper display device.
Owner:HONG FU JIN PRECISION IND (SHENZHEN) CO LTD +1

Nano-micellar preparation of anthracylcline antitumor antibiotics encapsulated by the phosphatide derivatized with polyethylene glycol

The present invention provides a nano-micellar preparation of anthracycline antitumor antibiotics for intravenous injection, which comprises a therapeutically effective amount of anthracycline antitumor antibiotics, a phosphatide derivatized with polyethylene glycol, together with pharmaceutically acceptable adjuvants. The preparation is prepared by encapsulating the medicament with a nano-micelle to obtain the nano-micellar preparation of anthracycline antitumor antibiotics for injection. The anthracycline antitumor antibiotics and the phosphatide derivatized with polyethylene glycol form a nano-micelle with a highly homogeneous particle size. In the micelle, the hydrophobic core of encapsulated medicament is surrounded by polyethylene glycol molecules to form a hydrophilic protective layer, so that the medicament is prevented from contacting with the enzymes and other protein molecules in blood and being recognized and phagocytozed by reticuloendothelial system in the body, and the circulation time in vivo of the micelle is prolonged.
Owner:INSITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES

Method for inducing synovium mesenchymal stem cells to be differentiated to chondrocytes by in-vitro lentivirus mediated BMP-2 (Bone Morphogenetic Protein) genes

The invention relates to a method for inducing synovium mesenchymal stem cells (SMSCs) to be differentiated to chondrocytes by in-vitro lentivirus mediated BMP-2 (Bone Morphogenetic Protein) genes. The method comprises the following steps of: separating and culturing synovium mesenchymal stem cells; constructing a recombinant plasmid pFUGW-oBMP-2; preparing morbus virosus of transfected lentivirus; and transfecting synovium mesenchymal stem cells by the morbus virosus of transfected lentivirus, wherein in the step of preparing morbus virosus of transfected lentivirus, the transfected lentivirus is jointly formed by the recombinant plasmid pFUGW-oBMP-2 and a packaging plasmid; and in the step of transfecting synovium mesenchymal stem cells by the morbus virosus of transfected lentivirus, synovium mesenchymal stem cells over third generation is taken to be mixed with the morbus virosus of transfected lentivirus, and then added into incomplete chondroblast inducing culture liquid to induce so as to obtain chondrocytes. SMSCs transfected by the transfected lentivirus provided by the invention are safe enough and can be spontaneously differentiated to cartilage in vitro.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

3D (Three-Dimensional) structure electrode and preparation method thereof

The invention relates to the technical field of energy storage, provides a 3D (Three-Dimensional) structure electrode and a preparation method thereof, and aims to solve the problems that in an existing carbon nitride-containing electrode material, the binding force between carbon nitride and a matrix material is weak, the nitrogen loss rate is high, and the preparation technology is complicated.The preparation method comprises the following steps: putting a nitrogen-containing raw material and a porous 3D matrix on a reaction carrier; heating the nitrogen-containing raw material and the porous 3D matrix in inert atmosphere, thus obtaining the 3D structure electrode, wherein a binding agent and a solution are not required. The preparation method is different from a method of binding the carbon nitride and graphite felt by utilizing polyvinylidene fluoride as the binding agent in the prior art, and is characterized by heating and drying the nitrogen-containing raw material, sublimatingthe nitrogen-containing raw material to the surface or the inner part of the porous 3D matrix and generating the carbon nitride through in-situ reaction, thus forming the 3D structure electrode. Thebinding force between the carbon nitride and the porous 3D matrix is remarkably enhanced, the nitrogen loss rate is reduced, the preparation technology is simple, and the battery performance can be increased.
Owner:SICHUAN UNIV

High-strength alloy cast aluminum spiral-flow constant-pressure pump material and preparing method and application of high-strength alloy cast aluminum spiral-flow constant-pressure pump material

The invention relates to a high-strength alloy cast aluminum spiral-flow constant-pressure pump material and a preparing method and application of the high-strength alloy cast aluminum spiral-flow constant-pressure pump material. The technical problem that the requirement for small weight of fire extinguishing pumps and the requirement for corrosion resistance of the pumps of the petrochemical industry cannot be met through an existing spiral-flow constant-pressure pump material is solved. The material comprises, by mass percent, 4.7-5.4% of Cu, 0.05-0.2% of Zr, 0.3-0.5% of Mn, 0.005-0.015% of B, 0.05-0.25% of V, smaller than 0.05% of Mg, 0.15-0.35% of Ti, smaller than 0.15% of Fe, smaller than 0.08% of Si, 0.15-0.25% of Cd and the balance Al. The invention further provides the preparing method and application of the high-strength alloy cast aluminum spiral-flow constant-pressure pump material. The high-strength alloy cast aluminum spiral-flow constant-pressure pump material can be widely applied to the field of manufacturing of spiral-flow constant-pressure pump materials.
Owner:SHANDONG HAOAN GOLDTECH NEW MATERIALS

Hotpot Chongqin noodle seasoning and preparation method thereof

The invention relates to the field of food processing technology, specifically to hotpot Chongqin noodle seasoning and a preparation method thereof. Raw materials of the hotpot Chongqin noodle seasoning include soybean oil, tea oil, thick broad-bean sauce, rapeseed oil, salt, fermented soya bean, bee pollen, monosodium glutamate, dried chilli, pickled ginger, chicken essence, pickled chilli, garlic, Chinese prickly ash, liquor and rock sugar. The preparation method comprises the following steps: crushing the above raw materials and soaking to form moistened particles, stir-frying the moistened particles and spices, stirring and cooling to obtain the Chongqin noodle seasoning product. The overall preparation technology is more complex than a preparation technology of traditional Chongqin noodle seasoning. The hotpot Chongqin noodle seasoning has Chongqin hotpot special flavor, and is spicy, fragrant, delicious and palatable. No preservative is added in the seasoning. Water content of the seasoning is controlled within 5-7%. Thus, the Chongqin noodle seasoning is not easy to deteriorate. With tea oil, bee pollen and kaempferia galamga, nutritional value of the Chongqin noodle seasoning is comprehensively raised. Thus, the product is beneficial to health diet for consumers and is convenient for promotion and extensive operating.
Owner:重庆刘一手餐饮管理有限公司
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