483results about How to "Safe and efficient" patented technology

A brachytherapy application device is described, which includes a tandem having a transparent region at its front end, and which is coupled with a fiber-optic illumination means and endoscope. This improved tandem assembly allows the user to guide the tandem into the uterus of a patient in a safer, more reproducible manner with the reduction in occurrence of uterine perforation during tandem advancement and placement.

A biodegradable cross-linked cationic multi-block copolymer of linear polyethylenimine (LPEI) wherein the LPEI blocks are linked together by hydrophilic linkers with a biodegradable disulfide bond and methods of making thereof. The biodegradable cross-linked cationic multi-block copolymer may also contain pendant functional moieties which are preferably receptor ligands, membrane permeating agents, endosomolytic agents, nuclear localization sequences, pH sensitive endosomolytic peptides, chromogenic or fluorescent dyes.

Disclosed is a cross-linked branched poly(alkylenimine) and compositions thereof and nucleotide molecules. Also disclosed are methods for preparing the cross-linked branched poly(alkylenimine).

A method of treating a subject having a musculoskeletal disorder includes administering to a subject's articular site in need thereof an effective amount of a hyaluronic acid (HA) composition. In one embodiment, the HA composition includes an HA derivative, wherein carboxyl functionalities of the hyaluronic acid derivative are each independently derivatized to include an N-acylurea or 0-acyl isourea, or both N-acylurea and 0-acyl isourea. In another embodiment, the HA composition includes a crosslinked HA gel that is prepared by reacting an uncrosslinked HA with a biscarbodiimide in the presence of pH buffer in a range of between about 4 and about 8. The composite can optionally include at least one second bioactive agent other than the HA derivative, such as a steroid.

A medicament injection kit, for use in occluding a renal artery and a renal vein in a kidney and injecting a therapeutic medicament into the kidney so as to pressurize the kidney, includes: an artery catheter which includes a first balloon capable of occluding the renal artery; a vein catheter which includes a second balloon capable of occluding the renal vein; a syringe for injecting the therapeutic medicament, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter; and a syringe for pressurizing the inside of the kidney by injecting a liquid, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter.

A method and apparatus are disclosed for liquefying target tissue within a body and aspirating the same while leaving non-target tissue intact. A biocompatible fluid is heated and contacted with target tissue so that the target tissue is melted while non-target tissue remains intact. As the target tissue is being melted it is also aspirated from the body.

In a method for producing an encrypted method payload data stream comprising a header and a block containing encrypted payload data, a payload data key for a payload data encryption algorithm for encrypting payload data is generated. The payload data is encrypted using the generated payload data key and the payload data encryption algorithm to obtain the block containing the encrypted payload data of the payload stream. A part of the payload data stream is processed to deduce information marking the part of the payload data stream. The information is linked with the payload data by means of an invertible logic linkage to obtain a basic value. This basic value is finally encrypted using a key of two keys being different from each other by an asymmetrical encryption method, the two different keys being the public and the private keys respectively for the asymmetrical encryption method to obtain an output value being an encrypted version of the payload data key. The output value is finally entered into the header to complete the payload stream. Changes of the header and of the payload data itself, which are not authorized, lead to an automatic destruction of the payload data.

An automated system for loading low dose radioisotope seeds into a plurality of implant needles is comprised of a loading station into which a replaceable cartridge may be positioned. The cartridge is preloaded with a plurality of radioisotope seeds and a plurality of spacers. The cartridge has at least one aperture and preferably the radioisotope seeds and spacers are loaded around the periphery of a rotatable drum within the cartridge. The loading station has a cartridge receiving structure and an automated motion control system. When the cartridge is positioned in the cartridge receiving structure, the automated motion control system preferably drives a pair of stepper motors within the cartridge, one for rotating the rotatable drum and one for sliding a pushrod to selectively eject radioisotope seeds and spacers from the cartridge into each of a plurality of implant needles positioned so as to receive the radioisotopes seeds and spacers within the implant needle. In one embodiment, the implant needles are positioned tip first into the loading station, and once a predetermined arrangement of radioisotope seeds and spacers are loaded into the implant needle, a plug is positioned in the tip of the implant needle. Preferably, the automated system includes a computer processor having a touch screen user interface that is connected to and directs the operation of the automated motion control system to load the plurality of implant needles in accordance with a predetermined dose plan.

A vehicle convoy system for use in connection with a vehicle, wherein the vehicle includes at least one drive mechanism to impart drive to the vehicle, includes at least a first processor that is adapted to be placed in operative or communicative connection with the drive mechanism to effect control of the drive mechanism based upon data of the position of a leading vehicle in front of the vehicle so that the vehicle moves to follow movement of the leading vehicle. The vehicle can, for example, be a self-propelled wheelchair.

Methods of treating a well bore in a single trip are provided. A tubing string may be inserted into a subterranean formation having a well bore, where the tubing string has a locking device on an end. A workover tool may be positioned in a first zone of the subterranean formation, where the workover tool engages the locking device. One or more perforations may be created or enhanced in a first zone of a subterranean formation using the workover tool, and the tubing string may be positioned in a second zone of the subterranean formation. A fracturing fluid may be introduced into the first zone of the subterranean formation at a rate and pressure sufficient to create or enhance one or more fractures in the subterranean formation. The first zone of the subterranean formation may be isolated from the second zone of the subterranean formation and one or more perforations in the second zone of the subterranean formation may be created or enhanced using the workover tool.

An off-route recalculation method and apparatus for a navigation system calculates a new route when a vehicle is deviated from an originally calculated route to a destination. The method is comprised of the steps of: detecting whether a user vehicle has deviated from an originally calculated route; predicting a path that a user is likely to take until a new route to the destination is calculated; calculating a predicted distance that the user vehicle advances through the predicted path during a time the new route to the destination is calculated and during a turn prepare time, thereby determining a start position of the new route; calculating the new route to the destination incorporating the start position.

The invention relates to a food pressure cooking appliance including a bowl and a lid intended to be locked relative to the bowl to form with the latter a cooking chamber adapted to rise in pressure. The appliance also including bayonet locking means forming first and second series of protrusions that are integral with the envelope of the lid and the envelope of the bowl, respectively, and that are intended to cooperate with each other to ensure the locking of the lid relative to the bowl. Each protrusion of at least one of said series is consisted by a volume element that has opposite convex and concave faces, and that is formed by a localized radial deformation of the corresponding envelope.

Novel apparatus and methods for generating and transmitting an interruption signal to a request for a substantially autonomous vehicle taxi-service based on user-supplied input are presented. The disclosure provides an efficient technique for interrupting an initial request for a substantially autonomous vehicle taxi-service and in some embodiments, further enables for the rescheduling of the request for a substantially autonomous vehicle taxi-service to a future point in time based upon user supplied input.

A method and apparatus for acquiring and removing information regarding a digital rights object are provided. The method for acquiring removing information regarding a digital rights object includes receiving a request for data on a rights object from a device, processing the data on the rights object in response to the request, and providing the processed data to the device. The method of removing a digital rights object includes selecting information regarding a rights object to be removed, encrypting the selected information regarding the rights object using a common encryption key, embedding the encrypted information regarding the rights object into a signal to be transmitted to a portable storage device, and transmitting the signal to the portable storage device. A device requests information regarding a rights object from a portable storage device, receives the information regarding the rights object from the portable storage device, and removes an unnecessary rights object.

Group (including, without limitation, occupational work forces) safety and wellness monitoring utilizes baseline physiology testing and vital sign monitoring and sampling technologies. Aerobic capacity of individual members of a group is determined through initial baseline testing which results in an individual health risk assessment. Thereafter non-invasively observed and monitored during incremental work and exercise is commenced. Subsequent data collected is used for advance identification of personnel at risk of injury, such as during unexpected vital sign elevations that can signal early onset of fatigue and heat stress / dehydration prior to injury.

The invention discloses a method for eliminating a traffic conflict of two vehicles at an intersection without a signal. The method comprises the following steps: vehicle information collection and pretreatment; vehicle-to-vehicle conflict danger identification; vehicle-to-vehicle conflict type determination; determination on a conflict vehicle priority; determination on a conflict elimination strategy; and execution of the conflict elimination strategy. According to the method provided in the invention, driving security of vehicles can be improved and a road passing efficiency can also be enhanced.

Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.

A display rack transport device includes a wheel assembly and a display mount. The display mount is removably mountable to the wheel assembly and mountable to a display rack. Variously configured display mounts are adapted to mount to various styles of display racks, such as pallet racks, storage racks, and shelf racks. The wheel assembly includes one or more pivotally mounted wheels and is adapted to enable the display mount to raise and lower relative to the wheel assembly when the display mount is mounted to the wheel assembly. The raising and lowering of a display mount that is mounted to a display rack enables the display rack to be repositioned utilizing the pivoting wheels of the wheel assembly.

It is disclosed a method (70) for operating a storage and order-picking system (10) in which a plurality of manipulators (40) process a plurality of picking / storing orders in accordance with a manipulator-to-handling-unit principle, wherein the system (10) comprises a provision zone (12), a picking zone (14), a plurality of provision units (42, 62) in the provision zone, a plurality of, particularly stationary arranged, transfer locations (46) in the picking zone (14), a DTS (18) including a plurality of DTVs (20), and a controlling device (32), and wherein the method (70) comprises the following steps of: analyzing (S10) the plurality of picking / storing orders by the controlling device (32) for determining retrieval / delivery locations in the provision zone (12); setting (S12) of transfer actions (48) by selecting for each of the retrieval / delivery locations one or more of the transfer locations (46) in the picking zone (14) as delivery / retrieval location and by assigning the same thereto, wherein the delivery / retrieval location is located within an action zone (72) extending around the respective retrieval / delivery location and moving dynamically with the respective manipulator (40); generating (S14) an action order for each of the manipulators (40) by selecting some of the transfer actions (48), and setting a, particularly unidirectional, moving path (74) along which the respective manipulator (40) moves between the selected retrieval / delivery locations throughout the, preferably entire, picking zone (14); and generating (S16) transport orders for the DTVs (20) so that each of the manipulators (40), during performance of its action order, can perform its transfer actions (48) within its action zone (72), preferably without interruption.

The invention relates to a method and apparatus for safely producing hydrogen peroxide by injecting dispersed minute bubbles of hydrogen and oxygen into a rapidly flowing liquid medium. The minute bubbles are surrounded by the liquid medium of sufficient volume for preventing an explosive reaction between the hydrogen and oxygen. The liquid medium is formed of an acidic aqueous solution and a Group VIII metal catalyst. Hydrogen is sparged into the flowing medium for dissolution of the hydrogen in the medium. Oxygen bubbles are reacted with the dissolved hydrogen for producing hydrogen peroxide. Preferably, the liquid medium has a velocity of at least 10 feet per second for providing a bubbly flow regime in the reactor. The invention allows the direct combination of oxygen and hydrogen while preventing propagation of an explosive condition within the reactor. The method and apparatus provide for the safe production of hydrogen peroxide with low manufacturing costs.

A method and a system for assisting air traffic controllers that automatically detects conflicts between aircraft trajectories and selects the conflicts that can be solved by minor modification(s) of aircraft speed, climbing rates or descending rates and lateral shifts of route. Minor modifications are selected so as to not interfere with current controllers' decision making process thereby circumventing the basic rule of uniqueness of control in a given piece of airspace. The minor modifications are automatically transmitted to aircraft for execution without requiring controllers' prior agreement. Thus, the method solves most conflicts, such that the air traffic delivered to the controllers is free of most of the pre-existing conflicts.

Methods and apparatus for handling blowout preventer stacks. In one embodiment the handling system includes a cart, or skid, providing a base platform, a tilting frame, and a lifting frame. The stack is attached to the lifting frame, which is slidingly supported by the tilting frame, which pivots relative to the cart. The cart provides for positional adjustment of the stack in a first horizontal direction, while positional adjustment in a second, perpendicular horizontal direction is provided by a lateral adjustment mechanism coupling the tilting frame and the cart. The lifting frame can be moved vertically relative to the cart and also provides for rotational adjustment of the stack about its central axis.

A blood collection assembly includes a hub with a distal end, a proximal end, a hub outer surface and an internal opening extending therethrough. The assembly also includes a holder housing defining a receiving chamber and having a rearward end adapted to receive a sample collection tube within the chamber and a forward end including a receiving port extending into the chamber, where the receiving port receives a portion of the proximal end of the hub therein. An internal opening of the hub accommodates a puncturing element at the proximal end thereof for providing passage of a fluid therethrough, and the puncturing element contacts the sample collection tube. The hub and the holder housing include an interengaging structure extending substantially perimetrically therearound for axially locking the hub with the holder housing.

The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.

The invention provides a novel method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment / amelioration of diseases characterized by excessive loss of bone mass, e.g. osteoporosis. Down-regulation is effected by inducing an immune response against OPGL in an individual in need thereof. Immune responses can be raised by classical immunization with immunogenic variants of OPGL or by nucleic acid immunization where the nucleic acids encode the OPGL variant. The invention also pertains to compositions, polypeptides and nucleic acids useful in the invention, as well as to vectors and transformed host cells useful in the preparation thereof.

Laser ablation is used in curettage to treat periodontal disease. After an initial step of ablating afflicted tissues, an anti-microbial rinse is applied. A flexible fiber optic guide is the preferred means of directing radiant energy to the afflicted tissues. Sulcular disinfection may also be achieved by similar associated processes. Various anti-microbial agents and laser sources are disclosed.

An elliptic curve cryptography method which generates a public key for use in a communication encryption using an elliptic curve, including: changing a number of a secret key (d) of (k) bits to an odd number; encoding the secret key to yield an encoded secret key (d) in which a most significant bit (MSB) is (1) and a rest positional number is (1) or (−1); and computing the public key (Q=Dp) by multiplying the encoded secret key (d) by a predetermined point (P) on the elliptic curve by a scalar multiplication.

An apparatus and method for modifying the temperature and aromatically conditioning the air and surfaces within a bed environment. In preferred embodiments, the invention is a self-contained, forced air bed warmer or bed warmer / cooler and aromatic infuser which pre-heats, pre-cools and infuses aromatic influences into the interior sheets and covers of a bed to provide a controlled micro-environment that facilitates relaxation into restful sleep on cold or hot nights. Preferred embodiments include an air conditioning section comprising a body portion and a handle portion, said air conditioning section having an exterior surface that is adapted to receive the edge of a bed cover between said body portion and said handle portion; a fan; a heat transfer element; a temperature sensor; a control circuit connected to said temperature sensor; a timer mounted within said air conditioning section; an elongated air delivery section having two ends with an air entrance at one end and a primary air exit at the other end and a means for introducing aromatic influences into the air moving through it.