The invention discloses a multi-sensor integrated unmanned plane perception and circumvention simulation system, and the system comprises a system configuration module, an ADS, a B data module, an unmanned plane simulation module, a sensor data simulation module, and a perception and circumvention algorithm module, wherein all the above modules are connected to a system data pool, and carry out mutual interaction through the system data pool. The invention also discloses a corresponding simulation method, and solves problems that a conventional unmanned plane perception and circumvention system design method is high in cost, is high in testing risk coefficient, and is low in efficiency.