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43results about How to "Minimizing and eliminating" patented technology

Anti-mutated kras t cell receptors

Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for an HLA-A11-restricted epitope of mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) (KRAS7-16), Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog (NRAS), or Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS). Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Owner:UNITED STATES OF AMERICA

Autonomous identification of an anomalous aqueous stream from an aqueous source feeding multiple independent streams and remediation directive determination thereof

Aqueous streams are ubiquitous in everyday life. Aqueous streams are invariably an essential element in most residential, commercial, and industrial environments. In residential and commercial environments, aqueous streams are utilized in indoor and outdoor applications. Indoor applications may include, but are not limited to, lavatories, showers, tubs, toilets, laundry, ice-making, drink dispensing, dish washing, pot fillers, laboratory, cooling and refrigeration, and heating. Outdoor applications may include, but are not limited to, landscaping, water features, spas, pools, washing, or even water attractions in the case of entertainment parks. Provided herein are systems, methods, and devices for identification of an anomalous aqueous stream from an aqueous source feeding multiple independent streams and remedial action directive determination thereof.
Owner:THUM MARGARET LEE

Method for manufacturing an optical fiber preform by mcvd

Disclosed is a method for manufacturing an optical fiber preform in MCVD, which simultaneously performs an etching process for injecting a reaction gas for etching into a tube and a collapsing process for heating and collapsing the tube in order to minimize or eliminate an index dip existing at the center of the preform core. By using this method, the index dip phenomenon of the optical fiber preform can be minimized or eliminated, so it is possible to make an optical fiber having improved optical characteristics, particularly having improvement in a bandwidth and a polarization mode dispersion (PMD).
Owner:LG CABLE LTD (KR)

Method of induction weld forming with shear displacement step

A shear-assisted solid state welding method for joining of metal parts, involves a first step of heating opposing surfaces in a non-passivating environment to a temperature in the hot working temperature range of the metal. A second step involves bringing the opposing surfaces into contact while still in the hot working temperature range, and applying compressive stress sufficient to substantially prevent sliding in response to shear displacement, causing plastic flow in the hot layers. A third step involves imposing relative shear displacement of the metal work pieces without disengaging the opposing surfaces. The shear displacement induces plastic shear strain within the hot layers to progressively induce bonding.
Owner:NOETIC TECH INC

T cell receptors recognizing hla-cw8 restricted mutated kras

Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Owner:UNITED STATES OF AMERICA
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