35results about How to "Minimize skin irritation" patented technology

[Problem] To provide a fixing device for a tubular member such as a catheter which is easy to operate, has parts which are easy to tighten, which makes it easy to recognize whether the parts are securely fixed, which is small in size, and which causes minimum irritation of the skin.[Means for Resolution] A tubular member fixing device includes: a second fixing portion (20) being formed of soft material and including a retaining portion (22) capable of opening and closing for clamping the tubular member (30) and a second base member (21) formed integrally with the retaining portion (22) at a fitting recess (24); and a first fixing portion (1) being formed of material harder than that of the second fixing portion (20) and including a first base member (2) having a covering portion (3) for covering the outer surface (22d) of the retaining portion (22) so as to be capable of opening and closing the opening-closing side of the retaining portion (22) of the second fixing portion (20), and a fitting joint (2a) formed integrally with the covering portion (3) for fitting into the fitting recess (24) of the second fixing portion (20), and the second fixing portion (20) and the first fixing portion (1) are fitted to abut against each other.

An electrical shaver particularly useful for wet shaving includes a manually-grippable housing, and a cutter head removably attachable thereto along the outer edge of the cutter head. The cutter head includes at least one relatively sharp scraper edge located between the outer side of at least one cutter unit and the outer edge of the cutter head, but does not extend to the inner side of the cutter unit facing an adjacent cutter unit, such that the scraper edge is pressable into the skin, forwardly of the respective cutter unit, to erect hairs in the skin and to tauten the skin in advance of the respective cutter unit, with minimal irritation of the skin, as the cutter head is moved across the skin in the direction from the outer side towards the inner side of the respective cutter unit.

The present invention is an individual pressure barrier pouch that is used in conjunction with the assembly of either a one piece or a two piece ostomy appliance or as a pressure barrier pouch that can be preassembled and integrated into the assembly of a two piece ostomy appliance. In all three embodiments, body waste material / excretions from the patient's stoma / fistula pass through the pressure barrier pouch to enter the ostomy pouch. When pressure is applied to the ostomy pouch, the excretions no longer have access to escape through the path of least resistance between the stoma and the wafer stoma clearance hole as they do with a conventional ostomy pouch. The only access to the path of least resistance with the present invention would have body excretions backing up through the pressure barrier pouch.

The present invention relates to a transdermal composition of an antivomiting agent, and more particularly to a transdermal composition of an antivomiting agent which can minimize skin irritation by employing tropisetron as the antivomiting agent as well as by adjusting its pH to be in the range of 8 to 9 thus enhancing its rate of skin penetration thereby reducing the amount of a skin penetration enhancer used.