35results about How to "Minimize skin irritation" patented technology

Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and / or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin.

Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and / or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin.

Compositions including zinc compounds and select amino acids in a carrier base, and methods of skin treatment with such compositions, are described. The compositions are useful for healing skin and minimizing the irritation incurred from contact with the zinc compound without loss of zinc availability during absorption into the integument.

Disclosed is a transdermal delivery system of multiple adhesive layers having a drug-free adhesive layer as an intermediate layer to control drug delivery rate. The transdermal delivery system enhances transdermal delivery rate in the early stage after application on skin and provides sustained control of the drug delivery rate in the intermediate and later stages. Thus, the drug delivery rate effective for treatment can be controlled in a sustained manner.

Iontophoretic patches for the delivery of anti-migraine compounds and methods of using the patches are described.

A medical patch system has a first medical patch including an outer locating ring secureable to a surface and an inner patch, separable from the outer locating ring, disposed within the outer locating ring. The medical patch system includes a second medical patch adapted for insertion into the central area bounded by the outer locating ring after the inner patch is separated from the outer locating ring. The second medical patch includes a second outer locating ring secureable to the surface, and a second inner patch section, separable from the second outer locating ring, disposed within a second central area bounded by the second outer locating ring. The first and second outer locating rings have adhesive layers for securing the outer locating rings to a surface. The adhesive layers on the respective outer locating rings have different sizes, shapes or patterns to minimize skin irritation.

A knit sock useful for patients susceptible to foot problems resulting from diabetes or other conditions includes a leg section and a foot section. The leg section has sufficient expandability to be drawn over and cover at least a portion of a leg of a wearer. The foot section includes a heel section, a toe section, a sole section, and an instep section. The instep includes a ventilation panel and a flex zone, each having a different stitch construction. The ventilation panel allows air to pass through the sock and the flex zone prevents bunching or wrinkling of the material against the skin of the foot.

Compositions including zinc compounds and select amino acids in a carrier base, and methods of skin treatment with such compositions, are described. The compositions are useful for healing skin and minimizing the irritation incurred from contact with the zinc compound without loss of zinc availability during absorption into the integument.

A knit sock useful for patients susceptible to foot problems resulting from diabetes or other conditions includes a leg section and a foot section. The leg section has sufficient expandability to be drawn over and cover at least a portion of a leg of a wearer. The foot section includes a heel section, a toe section, a sole section, and an instep section. The instep includes a ventilation panel and a flex zone, each having a different stitch construction. The ventilation panel allows air to pass through the sock and the flex zone prevents bunching or wrinkling of the material against the skin of the foot.

A system for stimulating a nerve or nerves in a patient includes an electrode patch having an array of equally spaced concentric electrodes each having a central cathode and a concentrically surrounding anode. The electrode array patch is used to determine the location of the nerve or nerves to be stimulated by electrical pulses. Once the location of the nerve is determined, a concentric electrode patch having a central cathode and a concentrically surrounding anode is positioned at the optimal location on the patient's skin to effect neurostimulation. The concentric electrode patch may be removably affixed to the patient's skin by adhesive or magnets.

Apparatus for providing transcutaneous electrical nerve stimulation (TENS) therapy to a user, the apparatus comprising: a stimulation unit for electrically stimulating at least one nerve of the user; an electrode array connectable to the stimulation unit, the electrode array comprising a plurality of electrodes for electrical stimulation of the at least one nerve of the user; a monitoring unit electrically connected to the stimulation unit for monitoring the on-skin status of the electrode array; an analysis unit for analyzing the on-skin status of the electrode array to determine the effective on-skin time of the electrode array; and a feedback unit for alerting the user when the analysis unit determine that the effective on-skin time exceeds a threshold.

The present invention concerns stabilized cosmetic material containing triple-encapsulated retinol. Unstable, fat-soluble retinol is stabilized firstly by addition into vesicles consisting of nonionic surface-active agent, cholesterol and cholesteryl ester. The firstly stabilized retinol(vesicle) is subsequently inserted into sphingosomes (a kind of multi lamellar liposome) consisting of lecithin and ceramide. Finally the double-encapsulated retinol (sphingosome) is inserted into lamellar liquid-crystal emulsifying base, thereby being triply encapsulated.

[Problem] To provide a fixing device for a tubular member such as a catheter which is easy to operate, has parts which are easy to tighten, which makes it easy to recognize whether the parts are securely fixed, which is small in size, and which causes minimum irritation of the skin.[Means for Resolution] A tubular member fixing device includes: a second fixing portion (20) being formed of soft material and including a retaining portion (22) capable of opening and closing for clamping the tubular member (30) and a second base member (21) formed integrally with the retaining portion (22) at a fitting recess (24); and a first fixing portion (1) being formed of material harder than that of the second fixing portion (20) and including a first base member (2) having a covering portion (3) for covering the outer surface (22d) of the retaining portion (22) so as to be capable of opening and closing the opening-closing side of the retaining portion (22) of the second fixing portion (20), and a fitting joint (2a) formed integrally with the covering portion (3) for fitting into the fitting recess (24) of the second fixing portion (20), and the second fixing portion (20) and the first fixing portion (1) are fitted to abut against each other.

Iontophoretic patches for the delivery of anti-migraine compounds and methods of using the patches are described.

Apparatus for providing transcutaneous electrical nerve stimulation (TENS) therapy to a user, the apparatus comprising: a stimulation unit for electrically stimulating at least one nerve of the user; an electrode array connectable to the stimulation unit, the electrode array comprising a plurality of electrodes for electrical stimulation of the at least one nerve of the user; a monitoring unit electrically connected to the stimulation unit for monitoring the on-skin status of the electrode array; an analysis unit for analyzing the on-skin status of the electrode array to determine the effective on-skin time of the electrode array; and a feedback unit for alerting the user when the analysis unit determine that the effective on-skin time exceeds a threshold.

An electrical shaver particularly useful for wet shaving includes a manually-grippable housing, and a cutter head removably attachable thereto along the outer edge of the cutter head. The cutter head includes at least one relatively sharp scraper edge located between the outer side of at least one cutter unit and the outer edge of the cutter head, but does not extend to the inner side of the cutter unit facing an adjacent cutter unit, such that the scraper edge is pressable into the skin, forwardly of the respective cutter unit, to erect hairs in the skin and to tauten the skin in advance of the respective cutter unit, with minimal irritation of the skin, as the cutter head is moved across the skin in the direction from the outer side towards the inner side of the respective cutter unit.

An electrical shaver particularly useful for wet shaving includes a manually-grippable housing, and a cutter head removably attachable thereto along the outer edge of the cutter head. The cutter head includes at least one relatively sharp scraper edge located between the outer side of at least one cutter unit and the outer edge of the cutter head, but does not extend to the inner side of the cutter unit facing an adjacent cutter unit, such that the scraper edge is pressable into the skin, forwardly of the respective cutter unit, to erect hairs in the skin and to tauten the skin in advance of the respective cutter unit, with minimal irritation of the skin, as the cutter head is moved across the skin in the direction from the outer side towards the inner side of the respective cutter unit.

The present invention relates to polymer composite particles containing a sunscreen agent and a manufacturing method thereof, and more particularly, to circular-shaped polymer composite particles which are a hybrid of circular-shaped polymer particles and a sunscreen agent, drastically improve dispersion stability of particles themselves, provide excellent ultraviolet absorption performance and are applicable to cosmetics, and a manufacturing method thereof.

Disclosed is a transdermal delivery system of multiple adhesive layers having a drug-free adhesive layer as an intermediate layer to control drug delivery rate. The transdermal delivery system enhances transdermal delivery rate in the early stage after application on skin and provides sustained control of the drug delivery rate in the intermediate and later stages. Thus, the drug delivery rate effective for treatment can be controlled in a sustained manner.

The disclosed invention provides sweat sensing devices with smart sweat stimulation and sensing embodiments: which improve the dependability and predictability of sweat sampling rates; achieve a desired number of sweat sampling events per day while minimizing skin irritation and prolonging device lifespan; and use physical, optical or thermal sweat stimulation to augment or replace chemical sweat stimulation.

The present invention is an individual pressure barrier pouch that is used in conjunction with the assembly of either a one piece or a two piece ostomy appliance or as a pressure barrier pouch that can be preassembled and integrated into the assembly of a two piece ostomy appliance. In all three embodiments, body waste material / excretions from the patient's stoma / fistula pass through the pressure barrier pouch to enter the ostomy pouch. When pressure is applied to the ostomy pouch, the excretions no longer have access to escape through the path of least resistance between the stoma and the wafer stoma clearance hole as they do with a conventional ostomy pouch. The only access to the path of least resistance with the present invention would have body excretions backing up through the pressure barrier pouch.

The disclosed invention provides sweat sensing devices with smart sweat stimulation and sensing embodiments: which improve the dependability and predictability of sweat sampling rates; achieve a desired number of sweat sampling events per day while minimizing skin irritation and prolonging device lifespan; and use physical, optical or thermal sweat stimulation to augment or replace chemical sweat stimulation.

The present invention relates to a transdermal composition of an antivomiting agent, and more particularly to a transdermal composition of an antivomiting agent which can minimize skin irritation by employing tropisetron as the antivomiting agent as well as by adjusting its pH to be in the range of 8 to 9 thus enhancing its rate of skin penetration thereby reducing the amount of a skin penetration enhancer used.

A cosmetic composition for peel-off-type packs includes a thickener so that pearl or powder particles are stabilized in a formulation to thus impart a sophisticated and differentiated appearance. The content of an alcohol ingredient therein is controlled to accelerate drying, which maximizes a lifting effect. Silicone, imparting a feeling of conditioning, is introduced into polyvinyl alcohol and polyvinyl pyrrolidone, which are film formers, thus minimizing skin irritation upon peeling off.

Certain embodiments of the invention relates to a transdermal drug delivery system containing donepezil or a pharmaceutically acceptable salt thereof as an active ingredient, more specifically to a transdermal drug delivery system containing a drug-containing matrix layer comprising donepezil or its pharmaceutically acceptable salt, a styrene copolymer, a hydrogenated rosin glycerol ester, and optionally a hydrocarbon resin.

The present invention relates to a washing composition comprising a powder of which surface is hydrophobic, and more specifically, relates to a washing composition comprising a powder in which an alkyl group of a surfactant attached to the surface thereof is oriented towards an outermost shell, thereby the surface of the powder being hydrophobically modified.

The present invention relates to a medical infusion pump holder wearable as a glove, band, or sleeve that fits over the hand, arm, or leg of a patient and holds a medical infusion pump stationary proximate an injection site on the patient while the patient's arms or legs are in motion. The medical infusion pump holder comprises a receptacle that is formed from a flexible mesh material having a plurality of holes dispersed throughout. The medical infusion pump is inserted into the receptacle with only the intravenous drug delivery tube egress from the receptacle. A bottom seal is integrated around the periphery of the bottom end and closes the bottom end, and a top seal is fastened around the periphery of the top end. The top seal is stretchable and under a no-load condition draws the top end substantially closed retaining the medical infusion pump inside the receptacle.

A field of view enlarging clip-on mirror for use in combination with eyewear is provided. The field of view enlarging clip-on mirror includes a clip member having a clip insert designed to clip on the nose pad of eyewear. A mirror is attached to the clip member via a stem member. The mirror is designed to increase the field of view of the wearer providing a low cost, simple solution to alleviate the disadvantages caused to sufferers of Homonymous-Hemianopsia.