The invention discloses an intelligent half-bridge sine wave voltage conversion circuit based on PFC interleaved flyback, which comprises an input rectifier filter unit, a PFC boost unit, an interleaved flyback isolation conversion unit, a DC filter unit and an inverter phase inversion unit, wherein the interleaved flyback isolation conversion unit comprises a first switch transistor, a second switch transistor, a first transformer, a second transformer, a first diode, a second diode, a third diode and a fourth diode; the DC filter unit comprises a first capacitor and a second capacitor, the cathode of the third diode is connected with the back-end ground through the first capacitor, and the anode of the fourth diode is connected with the back-end ground through the second capacitor; and the inverter phase inversion unit comprises a fourth switch transistor, a fifth switch transistor, a third electrolytic capacitor, a fourth electrolytic capacitor and a filter inductor, and the back end of the filter inductor and the negative electrode of the third electrolytic capacitor serve as output ends of the inverter phase inversion unit. the filter inductor can be used for filtering high-frequency pulses, load can acquire excellent power frequency sine wave AC, and the circuit cost is reduced at the same time.