The invention discloses a multi-directional efficient heat dissipation dustproof high-frequency switch direct-current power supply integrated cabinet which is characterized in that balance strips are adhered to front, rear, left and right side surfaces of a cabinet body base, a base is arranged below the cabinet body base, a shell is welded to an upper surface of the cabinet body base, a cooling water tank is arranged on the left side of the shell, and a cooling fan is arranged on the right side of the cooling water tank; a cleaning structure is arranged on an outer side of the rotating rod, a dustproof net is mounted at a bottom end of the mounting frame, and a cabinet door is connected to a front end of the shell through hinges. The dust-proof high-frequency switch direct-current power supply integrated cabinet with the multidirectional efficient heat dissipation function is convenient to adjust the balance degree of the outer shell and the cabinet body base, adapts to differential settlement of a foundation, expands a heat exchange surface, improves the heat exchange effect, is dust-proof, prevents air containing harmful substances from entering the inner shell to influence electric parts, is convenient to disassemble and assemble an air treatment structure, each connecting line is independently limited, so the connecting lines can be conveniently and independently operated.