The invention discloses a manufacturing method for a green and protective exercise book. The manufacturing method comprises the following steps that a, paper in yellow is selected as an inner core, kraft paper in yellow is selected as a cover, green printing ink is selected, and a food grade antibacterial component is added into the printing ink according to the proportion of 0.2 g / kg -0.4g / kg sothat printing ink can be prepared; b, before printing and inking, the front faces and the rear faces of the inner core and the cover are coated with an antibacterial coating; c, the inner core and thecover in the step a are printed with the printing ink according to a setting; and d, the printed inner core and the cover are bound into the green and protective exercise book according to set specifications. According to the manufacturing method for the green and protective exercise book, by controlling the paper color, fluorescent materials and the printing oil and changing the optical performance of the paper, the effects of reducing visual fatigue, protecting the eyesight and preventing nearsightedness are achieved; and in the printing process, the food grade antibacterial component harmless to the human health is added, the green and protective effect is achieved, and the green and health product is provided for a market.