352 results about "Test Strip (device)" patented technology

The present invention provides a method of measuring an analyte, such as glucose in a fluid sample, such as whole blood, by a reflectance reading device. The method includes making periodic intermediate calculations of analyte level and dynamically ascertaining when an analytical reaction has reached an end point. Once stable, the process stops making periodic calculations and reports the final, actual glucose concentration. According to an exemplary embodiment, the method is performed by a reflectance photometer using an analytical test strip containing reagents that react with an analyte of interest in the test fluid. The end point is determined by calculating an intermediate analyte level of the testing element at predetermined intervals and calculating a ratio value corresponding to the (n)th measurement to an (n-5)th measurement. When two consecutive ratio values are less than or equal to a predetermined value, the end point is deemed reached and the final analyte level ascertained.

A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.

A device for sampling body fluid, the device comprising, a main body, a lancet disposed within the main body, a carrier disposed within the main body fixedly attached to the lancet, a spring in communication with the lancet and the carrier, an annular space disposed within the main body adjacent the lancet, and a testing device for measuring a body fluid. The testing device may include micro-porous test strips, an electronic testing device, an optical / reflectance testing measuring device, or a visual inspection.

Devices for dispensing test strips and methods of using the same are provided. The subject devices are characterized by having a housing made of a cover and a base configured to retain a plurality of test strips. In certain embodiments, the height of the base is less than the height of each of the test strips, such that a portion of each of the test strips extends beyond the distal or top edge of the base. The subject devices may further be characterized as having a substantially air and moisture tight seal. In using the subject devices, a plurality of test strips stored in a subject device are provided. A single test strip is removed from the subject device by moving the test strip distal to the remaining test strips. Also provided by the subject invention are kits for use in practicing the subject methods.

An assay device, a fluid analyte sample separator device and methods for use of thereof for determining whether the integrity of a fluid analyte sample has been compromised and for contemporaneously assaying the sample for the presence or absence of multiple analytes, such as drugs of abuse. The device is composed of a housing having separate slots therein for insertion of one or more analyte test strips, one end of which protrudes from the housing, and one or more units of a sample integrity monitoring system. The device may be used in dipstick or cassette form. An analyte sample separator for division of sample and retention of uncontaminated sample for further testing is also provided. The analyte test strips and sample integrity monitoring system are replaceable, so that the panel of analytes and of sample condition parameters tested can be customized.

A blood glucose meter having a test strip port and an adjustable lancet device disposed at the same end of the device body is disclosed. The device body further includes an enclosure at the proximal end of the device body which houses a test strip storage vial and which facilitates one-handed opening and closing of the vial to simplify access to test strips contained therein. The enclosure is further provided with a window which allows the reading of the lot numbers on the label of the test strip vial therein without necessitating removal of the vial. A data connector is also provided on the device body for communication access, such as to upload data from other devices or to download data to other devices. By combining these multiple components into a single device body, the blood glucose meter requires fewer steps for sampling and testing, and makes device use easier and more convenient.

The present invention provides a method of measuring an analyte, such a glucose in a fluid sample, such as whole blood, by a reflectance reading device. The method includes making periodic intermediate calculations of analyte level and dynamically ascertaining when an analytical reaction has reached an end point. Once stable, the process stops making periodic calculations and reports the final, actual glucose concentration. According to an exemplary embodiment, the method is performed by a reflectance photometer using an analytical test strip containing reagents that react with an analyte of interest in the test fluid. The end point is determined by calculating an intermediate analyte level of the testing element at predetermined intervals and calculating a ratio value corresponding to the (n)th measurement to an (n-5)th measurement. When two consecutive ratio values are less than or equal to a predetermined value, the end point is deemed reached and the final analyte level ascertained.

Test strip device for accepting a liquid sample and forming an even fluid front across the test strip. When the sample is applied to a contacting surface, it runs down the surface where it collects between the contacting surface and a slope surface. As the sample collects, it evenly reaches fluid flow contact with an absorbent membrane. As a result, the sample forms an even fluid front across the membrane, improving the performance of the test strip device. Methods for using the device to accept a sample and to detect an analyte in the liquid sample are also provided.

Disclosed, in one aspect, is an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: a light source or sources, said light source / s emitting light incident upon at least two, spatially separated zones of the test strip; and a photodetector which detects light emanating from each of the two said zones; in a further aspect is disclosed an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: at least one light source incident upon a zone of the test strip; and at least two photodetectors both of which are able to detect some of the light emanating from the zone of the test strip illuminated by the light source.

The invention discloses a method an a system for intelligently identifying and reading an immunity-chromatography test strip and application thereof. The method comprises the following steps that: the immunity-chromatography test strip with a bar code is arranged in a test strip test jack; light emitted by a light source in a bar code identification circuit is irradiated on the bar code of the immunity-chromatography test strip with the bar code by a lens; the emitted light is converted into an electric signal by a photoelectric converter; the signal is transmitted to a CPU by an amplification and rectification circuit; and the CUP fetches an analysis programme corresponding the type of the immunity-chromatography test strip with the bar code according to the received electric signal from the bar code identification circuit. The system obtained according to the method has high intelligent degree and simple operation. The operator only needs to insert the immunity-chromatography test strip with the bar code in a designated position of the device and then makes a loading end of the immunity-chromatography test strip in contact with a sample so as to know the result of the test item by a display screen.

The invention belongs to the field of bio-medical instruments, and in particular relates to a system and a method for quantitative detection of test strips on the basis of continuous fluorescent-substance markers. The system comprises a continuous fluorescent-substance marker test strip, a test strip frame, a lighting system, an imaging system, a fluorescent image receiver, a signal amplifier, an analog / digital converter, a data processing-controlling system, an output display device, a printer, a keyboard and an IC card matched with the test strip. The data processing-controlling system reads parameters of the IC card and then controls the test strip frame to move so as to ensure that the light emitted by the lighting system is reflected via a dichroic mirror and then automatically scans the test strip; acquired characteristic wavelength reflection fluorescence is transmitted to the data processing-controlling system for optical density identification and concentration calculation via the fluorescent image receiver, the signal amplifier and the analog / digital converter; and the output display device displays results. The invention can quickly and accurately realize the quantitative or qualitative detection of single-component and multi-component samples. The system has the characteristics of high detection sensitivity, objective results, flexible use and the like.

Disclosed is a CMOS image sensor-based on quantum dot marking test strip quantitative detection system, which comprises a quantum dot marking test strip, a test strip frame, a scanning system, a CMOS image sensor, a data-processing device, an output display device, a printer, a keyboard and an IC card matched with the test strip. After reading the IC card parameters, the data-processing device controls the test strip to move, so that the scanning system can automatically scan a detection band and a quality control band of the test strip; the collected signals are transmitted to the data-processing device through the CMOS image sensor, so that the optical density of the detection band and the quality control band can be identified and processed with concentration computing and technical analysis; and the test results are transmitted to the output display device and displayed. The invention can accurately achieve one-component and multi-component quantitative, semi-quantitative or qualitative detection of samples and can dynamically monitor the immunochromatographic reaction process. The system has high sensitivity, objective result and flexible operation.

An extraction method and apparatus is provided for obtaining quick, safe and highly sensitive testing of any of a variety of body fluids including saliva, blood, urine or other fluids for drugs of abuse or other analytes. The apparatus includes a latchable extraction wand for obtaining body fluid samples from a subject which is adapted to maximize the portion of the body fluid sample that will go into a graduated bottle containing a buffer solution, and a testing device wherein the sample will be received and into which test strips can be inserted to determine levels of drugs of abuse or other analyte in the sample. In one of the methods of the invention, energy is imparted to the sample and buffer solution, such as by shaking, and this facilitates the reduction of sample viscosity, such as by promoting the breakdown of mucins when the sample is saliva.

The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No− is displayed on the LCD.

The present invention provides a lateral flow format and materials and methods for using the format in a variety of applications. More particularly, the present invention provides single-layer lateral flow formats, materials and methods for detecting the presence of an analyte using a test strip comprising a dry porous medium comprising a single hydrophilic matrix. Devices are also provided as well as methods of making and using the format. The format is particularly useful for diagnosis of physiological and genetic conditions. In addition, the present invention provides methods and materials for concentrating a reagent in a porous medium.

An elimination-absorber monitoring system addresses diaper-monitoring problems with a unique, low cost, multi-layer disposable sensor structure that absorbs small volumes of urine, yet allows most urine volume to flow unimpeded through it, and into the diaper below. When connected with a reusable, miniature monitor / indicator unit, the sensor presents a clear and on-going change of measurement condition upon experiencing a rapid influx into the diaper of a significant volume of urine, and / or upon a significant reduction in the available absorbency of the diaper's top surface. The sensor additionally provides recessed, protected elements for similarly presenting a clear and on-going change in measurement condition upon experiencing the presence of fecal matter. Further provided is the monitor unit employing narrow, widely-spaced, fast rise-time, fast transition-time pulses for conductivity measurement and alarm activation. The monitor and sensor are interconnected and attached to a diaper by particularly effective and unique means, and the monitor is equipped with a highly intuitive and convenient control interface, as well as improved assemblies for the transmission of audible and visual alarm indications. Also described is a convenient test-strip device which, when connected to the monitor / alarm unit of the system, can selectively simulate either a soiled or unsoiled elimination-absorber / sensor for test, caregiver-training or demonstration purposes.

An apparatus is presented for estimating the concentration of an analyte using a combined enzyme-spectroscopic method. Examples are provided for the detection of glucose and lactate. A sample of biological fluid is mixed or contacted with an enzyme specific to the analyte of interest, and the reacting fluid is probed with an optical system at wavelengths that includes at least one wavelength that is sensitive to the analyte concentration and at least one wavelength that is not sensitive to the analyte concentration. The optical system measures properties, such as optical density, and relates the measurements to concentration through a calibration of the system. A method is also provided for analyzing the data obtained from optical measurements of reactions of enzymes with biological fluids. These technologies may be applied to continuous or periodic patient sampling systems or to test strip type devices.

The present invention includes methods and devices for preventing interfering substances from affecting the accuracy of a lateral flow immunoassay. In preferred embodiments, a test strip includes a capturing zone that includes at least one mobile capturing reagent that separates at least one interfering substance from the analyte. The capturing zone is preferably located upstream of the sample application zone. In some embodiments, the reagent / conjugate zone is also located upstream of the sample application zone. The capturing zone may be located upstream, downstream, or overlapping with the reagent / conjugate zone in these embodiments. In other preferred embodiments, one or more mobile capturing reagents are included in the elution medium / running buffer. In yet other embodiments, the capturing reagent is incorporated into a sample collection device of a sample collection system, preferably separate from the chromatographic test strip. A lysis zone is also included in some preferred embodiments.

A sampling device for sampling body fluid includes a lancet for making an incision, a capillary tube for drawing-up body fluid from the incision, and a test strip affixed to an upper end of the capillary tube for receiving the fluid. An absorbent pad can be disposed between the test strip and capillary tube for spreading-out the fluid being transferred to the test strip. An on-site analyzer such as an optical analyzer and / or an electrochemical analyzer can be mounted in the device for analyzing the fluid. Alternatively, a test strip can be slid through a slot formed in the bottom end of the device so that by passing the device against the skin after an incision has been formed, the test strip will directly contact body fluid emanating from the incision.