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49 results about "Radiographic contrast media" patented technology
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Inventor
A material used to improve the visibility of internal bodily structures in an X ray image.
Injector
InactiveUS6929619B2Reduces and eliminates power connectionGood adhesionAutomatic syringesMedical devicesAxis of symmetryRadiographic contrast media
Owner:LIEBEL FLARSHEIM CO
Self-contained power-assisted syringe
A self-contained and hand-held power-assisted syringe is provided which is suitable for the controlled injection of fluid material during medical procedures such as coronary angiography procedures which utilize small-bore and small sized guide catheter systems. The present invention provides a greater degree of injection power on-demand than was previously possible in a portable and hand-held syringe; and it can deliver larger volumes of radiopaque contrast medium at greater pressures than was previously possible using a conventional manual syringe. The power assisted syringe, along with all components necessary for its effective use and operation, may be pre-packaged and steriled within a single container and then disposed of after use.
Owner:KIM DUCKSOO +2
Injectable bone-replacement mixture
InactiveUS20060041033A1Optimal radio-opacityGood biocompatibilityImpression capsSurgical adhesivesInjectable boneRadiographic contrast media
An injectable mixture for substituting bone tissue in situ comprises: A) a two-component powder / liquid bone cement which upon mixing forms a self-hardening cement paste; and B) a third component consisting of a liquid which essentially is non-miscible with the cement paste and which is suitable to be washed out after hardening of said mixture in situ, resulting in a porous bone substituting material; and C) an X-ray contrast agent which is an organic substance. The injectable bone substitute material for bone augmentation has adaptable mechanical properties, an optimal radio-opacity without any inorganic X-ray contrast agent and therefore good biocompatibility.
Owner:SYNTHES USA
Injector
InactiveUS20050038390A1Reduces and eliminates power connectionGood adhesionAutomatic syringesMedical devicesAxis of symmetryRadiographic contrast media
An injector 20 that may be used to deliver radiographic contrast media and / or flushing solution into a patient's vascular system for the purposes such as obtaining enhanced diagnostic x-ray images. The injector includes the following features: (1) a syringe mount 26 for attachment of a syringe 28 to the injector 20; (2) display 34 and controls 90 for volume and flow rates; (3) automatic limiting of the operating pressure of the injector 20 as determined by the selection of a flow rate; (4) a syringe cradle 48 having a warming capability; (5) a purge / retract trigger 36 for control of the injection procedure having intuitive direction (i.e., forward for injecting, reverse for filing), non-contact control transmission through the housing of an injector 20 for an improved seal integrity, a speed lock, and / or the ability to change the concentration and / or flow rate of media or other fluid during an injection procedure; (6) a switch to determine when the drive ram 46 is in a “home” position; (7) a “soft” on / off power switch separate from the injector; and (8) a structure to prevent rotation of the drive ram 46 about its axis of symmetry 76. Additionally, the injector system includes software for the control of various components.
Owner:LIEBEL FLARSHEIM CO
Bone cement mixture and x-ray contrast medium as well as method for their preparation
A bone cement mixture comprised of a polymer component containing an x-ray contrast medium and a monomer component, wherein the x-ray contrast medium is a polymer or copolymer having compounds of radio-opaque elements bonded thereto, or is in the form of substantially spherical polymer or copolymer particles with radio-opaque inorganic nano-particles dispersed therein.
Owner:HERAEUS KULZER
Self-contained power-assisted syringe
A self-contained and hand-held power-assisted syringe is provided which is suitable for the controlled injection of fluid material during medical procedures such as coronary angiography procedures which utilize small-bore and small sized guide catheter systems. The present invention provides a greater degree of injection power on-demand than was previously possible in a portable and hand-held syringe; and it can deliver larger volumes of radiopaque contrast medium at greater pressures than was previously possible using a conventional manual syringe. The power assisted syringe, along with all components necessary for its effective use and operation, may be pre-packaged and steriled within a single container and then disposed of after use.
Owner:KIM DUCKSOO +2
Injector
InactiveUS20050038386A1Reduces and eliminates power connectionGood adhesionAutomatic syringesMedical devicesAxis of symmetryMedicine
An injector 20 that may be used to deliver radiographic contrast media and / or flushing solution into a patient's vascular system for the purposes such as obtaining enhanced diagnostic x-ray images. The injector includes the following features: (1) a syringe mount 26 for attachment of a syringe 28 to the injector 20; (2) display 34 and controls 90 for volume and flow rates; (3) automatic limiting of the operating pressure of the injector 20 as determined by the selection of a flow rate; (4) a syringe cradle 48 having a warming capability; (5) a purge / retract trigger 36 for control of the injection procedure having intuitive direction (i.e., forward for injecting, reverse for filing), non-contact control transmission through the housing of an injector 20 for an improved seal integrity, a speed lock, and / or the ability to change the concentration and / or flow rate of media or other fluid during an injection procedure; (6) a switch to determine when the drive ram 46 is in a “home” position; (7) a “soft” on / off power switch separate from the injector; and (8) a structure to prevent rotation of the drive ram 46 about its axis of symmetry 76. Additionally, the injector system includes software for the control of various components.
Owner:LIEBEL FLARSHEIM CO
Liposome-containing radiographic contrast medium and preparation method thereof
InactiveUS20050084453A1Efficiently conveyedHigh selectivityDispersion deliveryX-ray constrast preparationsRadiographic contrast mediaWater soluble
A radiographic contrast medium is disclosed, comprising a liposome which is comprised of vesicles including a water- and soluble nonionic iodine compound, and the contrast medium containing substantially no chlorinated solvent. There is also disclosed a method of preparing the radiographic contrast medium using supercritical or subcritical carbon dioxide.
Owner:KONICA MINOLTA MEDICAL & GRAPHICS INC
Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
InactiveUS20060292077A1Easy loadingPrevent thrombosisOrganic active ingredientsSurgeryDendrimerRadiopaque agent
In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk material which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and / or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and / or pharmaceutical agents in combination with the present invention.
Owner:CORDIS CORP
Barium sulfate product
InactiveCN101331085APigmenting treatmentCalcium/strontium/barium sulfatesLiquid mediumRadiographic contrast media
This invention generally relates to a barium sulfate product particularly useful as an X-ray contrast agent in preparations administered for examination of the gastrointestinal tract and to processes for making the product from naturally occurring barite ore containing barium sulfate crystals and gangue materials. The process includes treating or contacting the barium sulfate-containing particles obtained from barite ore with a fluidizing agent in a liquid medium to remove gangue materials present therein.
Owner:MALLINCKRODT INC
Methods and systems for reducing substance-induced renal damage
InactiveUS20090182400A1Reduce severityReduce or avoid damageTherapeutic coolingTherapeutic heatingSubstance inducedContrast medium
Methods for reducing kidney damage induced by radiographic contrast medium or another nephrotoxic drug or substance administered to or generated by a patient include reducing the temperature of the patient by positioning an endovascular heat exchange device in a blood vessel of the patient and adjusting the temperature of the device to cause a reduction in the patient's temperature. The patient's temperature may be reduced prior to, during, and / or after, the administration of the contrast medium. The methods may also include administering an anti-shivering mechanism to the patient to reduce shivering caused by the reduction in the patient's temperature. The methods may also include disrupting the laminarity of blood flow around the device to enhance the temperature exchange between the device and the blood flowing around the device. The endovascular heat exchange device may be an endovascular heat exchange catheter. The device may be a component of a system, which includes a temperature controller in communication with the endovascular heat exchange device to reduce the temperature of the patient to reduce the temperature of the patient's kidneys.
Owner:ZOLL CIRCULATION
X-ray CT apparatus and method thereof
ActiveUS20110194668A1Material analysis using wave/particle radiationRadiation/particle handlingX-rayRadiographic Contrast Agent
In an X-ray CT apparatus 1 and an X-ray CT method, the thickness of an object to be inspected is computed on the basis of the number of transmitted X-rays in a specific energy range set above and below the K-absorption edge of an X-ray contrast medium serving as the object to be inspected, and a CT image is reconstructed on the basis of the computed thickness of the object to be inspected. Such X-ray CT apparatus 1 and X-ray CT method can generate an X-ray CT image stably and independently of the size of the object to be inspected and of X-ray tube voltage (X-ray energy distribution).
Owner:MITSUBISHI CHEM CORP
Bismuth particle X-ray contrast agents
Radiopaque bismuth particles and methods of making and using the radiopaque bismuth particles are disclosed. The radiopaque bismuth particles include an elemental bismuth core and an outer coating comprising one or more coating agents. Disclosed radiopaque bismuth particles are suitable for use in surgical sponges and plastic objects.
Owner:THE STATE OF OREGON ACTING BY & THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIV
Product for testing for dysphagia
InactiveUS20040086457A1Pleasant appearancePleasant tasteX-ray constrast preparationsBakery productsX-ray contrast mediaSwallow food
An orally ingestible baked radiopaque product comprising (a) fat, (b) sweetener, (c) moisturizing agent, (d) x-ray contrast agent, (e) flour and (f) optionally flavoring agent useful for evaluating swallowing food having a dry rood texture. The x-ray contrast agent is interspersed throughout the product by mixing it into the product prior to baking it. The product is used in the detection of dysphagia. A method and dough useful for preparing the product.
Owner:WANDAS BARIUM COOKIE L L C
Injector
InactiveUS20050038389A1Reduces and eliminates power connectionGood adhesionAutomatic syringesMedical devicesAxis of symmetryRadiographic contrast media
An injector 20 that may be used to deliver radiographic contrast media and / or flushing solution into a patient's vascular system for the purposes such as obtaining enhanced diagnostic x-ray images. The injector includes the following features: (1) a syringe mount 26 for attachment of a syringe 28 to the injector 20; (2) display 34 and controls 90 for volume and flow rates; (3) automatic limiting of the operating pressure of the injector 20 as determined by the selection of a flow rate; (4) a syringe cradle 48 having a warming capability; (5) a purge / retract trigger 36 for control of the injection procedure having intuitive direction (i.e., forward for injecting, reverse for filing), non-contact control transmission through the housing of an injector 20 for an improved seal integrity, a speed lock, and / or the ability to change the concentration and / or flow rate of media or other fluid during an injection procedure; (6) a switch to determine when the drive ram 46 is in a “home” position; (7) a “soft” on / off power switch separate from the injector; and (8) a structure to prevent rotation of the drive ram 46 about its axis of symmetry 76. Additionally, the injector system includes software for the control of various components.
Owner:LIEBEL FLARSHEIM CO
System and method for marking body cavities
Systems and methods for marking a body cavity. In one embodiment, a system includes means for inspecting a body cavity, and means for visibly marking the body cavity so as to convey visual information regarding the body cavity. In one embodiment, a method includes inspecting a body cavity and marking the body cavity with a marking material to provide a visual indication regarding the cavity. In one embodiment, a marking material for marking a body cavity includes a radiopaque contrast agent that is viewable through fluoroscopy and a colored dye that is viewable using an internal viewing device.
Owner:CR BARD INC
Synthetic methods of an impurity A and an impurity B of iopamidol
InactiveCN105461581ASimple categoryHigh purityOrganic compound preparationCarboxylic acid amides preparationRadiographic contrast mediaCombinatorial chemistry
The invention relates to synthetic methods of an impurity A and an impurity B of iopamidol that is a nonionic X-radiographic contrast medium. 5-amino-1,3-phthaloyl dichloride is adopted as an initial raw material. The impurity A and the impurity B of the iopamidol can provide qualified contrasts for quality control of the iopamidol.
Owner:ZHEJIANG HAIZHOU PHARMA CO LTD
Synthesis of N1,N3-BIS(2,3-DIHYDROXYPROPYL)-5-NITROISOPHTHALAMIDE
ActiveUS20140200367A1High purityOrganic compound preparationCarboxylic acid amides preparationIoversolCombinatorial chemistry
The present disclosure generally relates to a new process for the preparation of high purity 5-nitro-isophthalamide compounds, which are useful as intermediates for the preparation of imaging agents, such as iodinated x-ray contrast imaging agents like ioversol, iohexyl and iopamidol.
Owner:LIEBEL FLARSHEIM CO
Cineradiography-based method and apparatus for testing protective headgear
ActiveUS20200225133A1Improve clarityHelmetsHelmet coversProtective headgearRadiographic contrast media
A method and apparatus for testing the response of protective headgear 104 to impact forces. A high-speed cineradiography imaging system 100 is used to obtain full-field, time-resolved internal monitoring and measurement of headgear component (pads 140 and liners 142) deformation and interaction with a head surrogate (headform 102), deformation of headform components, and stress and strain transfer into the headform. Radiopaque contrast materials (144&148) and integration techniques are used to highlight specific regions of interest within the headgear and headform components during the impact loading events.
Owner:PETEL OREN
Liposome-containing radiographic contrast medium and preparation method thereof
InactiveUS20060018828A1Improve efficiencyHigh selectivityIn-vivo radioactive preparationsDispersion deliverySterolLiposome Vesicle
A method of pereparing a rediographic contrast medium containing liposomes is disclosed, comprising (a) dissolving a phospholipid and a sterol in a supercritical or subcritical carbon dioxide in the presence of a compound containing a hydroxyl group or a polyalkyleneoxide group, (b) adding thereto an aqueous solution containing an iodine compound to form micelles and (c) discharging the carbon dioxide to form liposomal vesicles enclosing the iodine compound.
Owner:KONICA MINOLTA MEDICAL & GRAPHICS INC
Low-osmotic-pressure triiodo-benzene compound contrast agent
ActiveCN102516116AOrganic compound preparationX-ray constrast preparationsN-methylacetamideRadiographic contrast media
The invention belongs to the field of nonionic monomer X-ray contrast agents, and relates to a triiodo-benzene compound contrast agent with excellent physicochemical properties and a preparation method of the compound. The compound is N,N-dimethyl-N'-(2,3-dihydroxy-n-propyl)-5-(N-methylacetamido)-2,4,6-triiodo-1,3-isophthalamide.
Owner:ZHEJIANG STARRY PHARMA
Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
ActiveUS20080177102A1Satisfies unmet needMaximizing intensityOrganic active ingredientsOrganic chemistryDendrimerRadiographic contrast media
In accordance with the present invention, a high intensity radiopaque contrast agent is disclosed. The agent may be coated on or incorporated within bulk materials, which may then be subsequently utilized to fabricate a radiopaque medical device. Primary effects through chemistry include higher radiopaque concentrations per unit weight of the radiopaque element or agent. Secondary effects include selective placement of the radiopaque elements which may further enhance the radiopacity of the device with reduced requirements of the radiopaque agent. Such a radiopaque contrast agent may be produced in various forms such as a dendrimer and / or incorporated as the end groups of polymeric chain. In addition one can incorporate biological and / or pharmaceutical agents in combination with the present invention.
Owner:CARDINAL HEALTH SWITZERLAND 515 GMBH
Process for the iodination of phenolic derivatives
ActiveUS8766003B2Organic compound preparationCarboxylic acid amides preparationRadiographic contrast mediaIodine
Owner:BRACCO IMAGINIG SPA
Liposome-containing radiographic contrast medium and preparation method thereof
InactiveCN1988919AImprove transport efficiencyHigh selectivityX-ray constrast preparationsOil/fats/waxes non-active ingredientsLipid formationIodide
A liposome-containing X-ray radiopaque dye comprising a water soluble iodide compound contained in a water phase inside and outside lipid membranes. The liposomes are produced by mixing lipid membrane components for constituting lipid membranes with carbon dioxide of supercritical or subcritical condition in the presence of at least one compound having a hydroxyl or polyalkylene oxide group. The obtained X-ray radiopaque dye containing these liposomes does not contain any toxic solvents, such as chlorinated solvents, so that high safety can be ensured.
Owner:KONICA MINOLTA MEDICAL & GRAPHICS INC
Liposome-containing radiographic contrast medium and preparation method thereof
InactiveUS7588751B2Improve efficiencyHigh selectivityIn-vivo radioactive preparationsDispersion deliveryLiposome VesicleSterol
A method of pereparing a rediographic contrast medium containing liposomes is disclosed, comprising (a) dissolving a phospholipid and a sterol in a supercritical or subcritical carbon dioxide in the presence of a compound containing a hydroxyl group or a polyalkyleneoxide group, (b) adding thereto an aqueous solution containing an iodine compound to form micelles and (c) discharging the carbon dioxide to form liposomal vesicles enclosing the iodine compound.
Owner:KONICA MINOLTA MEDICAL & GRAPHICS INC
Balloon with radiopaque adhesive
A radiopaque balloon with a composite wall having a radiopaque adhesive affixing inner and outer layers of the balloon. The radiopaque adhesive provides a radiographic image of the balloon wall with or without the use of a radiopaque contrast media to inflate the balloon. A radiographically fainter image is provided as the balloon is inflated with well-defined edges of a balloon image, and the total radiopacity of the balloon does not change as the balloon is inflated. Also, a method of imaging a balloon wall and a method of imaging a radiopaque adhesive between two layers of a balloon wall are provided.
Owner:CR BARD INC
X-ray contrast agent composition and its preparation method
InactiveCN1686570ASolve the problem of stable suspensionLow viscosityX-ray constrast preparationsRadiographic contrast mediaLiquid state
A composition as the X-ray contrast medium is prepared from solid reference material, surfactant, excipient, stabilizer, chelating agent, flavouring and water through mixing said solid reference material powder with surfactant and stabilizer, grinding, sequentially adding others, high-pressure homogenizing in liquid state, ageing, regulating pH=7-9 and degassing.
Owner:SHANDONG NORMAL UNIV
Process For The Iodination Of Phenolic Derivatives
ActiveUS20130072719A1Organic compound preparationCarboxylic acid amides preparationRadiographic contrast mediaContrast medium
The present invention relates to a process for the preparation of iodinated phenols; in particular; it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted phenol compounds to the corresponding 3,5-disubstituted-2,4,6-triiodophenols, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
Owner:BRACCO IMAGINIG SPA
Methods and systems for reducing substance-induced renal damage
InactiveUS7473270B1Reduce severityReduce or avoid damageTherapeutic coolingTherapeutic heatingSubstance inducedBlood vessel
Methods for reducing kidney damage induced by radiographic contrast medium or another nephrotoxic drug or substance administered to a patient include reducing the temperature of the patient by positioning an endovascular heat exchange device in a blood vessel of the patient and adjusting the temperature of the device to cause a reduction in the patient's temperature. The patient's temperature may be reduced prior to, during, and / or after, the administration of the contrast medium. The methods may also include administering an anti-shivering mechanism to the patient to reduce shivering caused by the reduction in the patient's temperature. The methods may also include disrupting the laminarity of blood flow around the device to enhance the temperature exchange between the device and the blood flowing around the device. The endovascular heat exchange device may be an endovascular heat exchange catheter. The device may be a component of a system, which includes a temperature controller in communication with the endovascular heat exchange device to reduce the temperature of the patient to reduce the temperature of the patient's kidneys.
Owner:ZOLL CIRCULATION
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