The present invention discloses a differential push-push voltage controlled oscillator and signal generation device, comprising a quadrature oscillator, two harmonic selection elements, two frequency multiplier circuits and a power combination element. The quadrature oscillator generates two orthogonal signals and respective harmonic signals, two harmonic selection elements are used for extracting secondary harmonics in two output signals of the oscillator, generating the output of a differential push-push signal; two frequency multiplier circuits are used for frequency multiplication of the signal, generating two frequency multiplier signals with the same phase; the power combination element achieves the combination of power of two signals with the same phase, forming the output of a single-end signal source. The signal source achieves the output of a differential push-push voltage controlled oscillator by a harmonic extraction and frequency multiplication manner, increases the output frequency of signals and utilizes two orthogonal oscillation signals in connection with a power combination manner to increase the output power of signals.