The invention discloses a paris polyphylla var.yunnanensis multi-bud cultivating method. The paris polyphylla var.yunnanensis multi-bud cultivating method comprises the steps of rhizome screening, rhizome treating, seedbed treating and final-period management. The method specially comprises the steps that in autumn and winter, underground rhizomes are excavated, the rhizomes which are free of disease and pest damages and grow robustly are selected, soaked with fungicide and dried in the air, the rhizomes are placed for 6-8 days under the dry and ventilation condition, main buds are excided, puncturing is carried out every 2-3 cm on one side of each rhizome, and the rhizomes are stored in humid river sand until to the spring next year after being soaked with cytokinin; the rhizomes are removed, and after plant growing accelerant soaking is carried out, field planting can be conducted; the treated rhizomes are placed onto a seedbed to be watered thoroughly once; by means of watering, the soil humidity can be kept, weeds are removed, and seedling can be out in spring next year. By means of the method, the germination number and the planting percent of single paris polyphylla var.yunnanensis can be increased; to a great extent, the germination time of the rhizomes can be shortened, the number of germination on the single rhizome can be increased, the seed yield of the single plant can be increased, and a good viewing function can be achieved.