The invention discloses a two-channel beam forming speech enhancement method based on noise mixed coherence. Adaptive beam forming can effectively inhibit directional noise signals under the reverberation-free condition, but the inhibiting effect of the adaptive beam forming is greatly reduced in the presence of reverberation. Aiming at the problem, the invention provides the two-channel beam forming method based on noise mixed coherence. Considering that coherence and scattering noises exist simultaneously in a sound field, in the method provided by the invention, the hypothesis of replacing the traditional scattering sound field with a mixed noise field is provided, specifically, the method comprises the following steps: firstly, estimating the noise coherence in the mixed noise field, estimating a power spectrum of the noises by utilizing the noise coherence, and calculating a gain function of a frequency domain filtering by using the estimated result for the power spectrum of the noises; and carrying out frequency domain filtering processing on the noises and reverberant signals, and carrying out further processing on the residual noises by adopting a minimum variance distortionless response beam forming device. The experiment proves that the quality of the speech enhanced by adopting the method provided by the invention is obviously improved compared with that enhanced by adopting the traditional method.