The present invention concerns a method and a kit, for the treatment of a selected area of the
skin and / or
subcutaneous tissue, and in particular for the cosmetic treatment of
skin conditions such as regional fat deposits including
cellulite. The method comprises heating the selected area to a sustained
skin temperature of about 32 to about 50° C. for a desired period of time, using a device comprising either a heat source capable of conductively heating the selected area or, alternatively, an infra-red source for emitting infra-red with a
wavelength from about 700 nm to about 15000 nm. The method also comprises administering, simultaneously or sequentially in either order, a composition containing an
active agent selected from the group comprising a skin active, a
nutrient absorption suppressant or a thermogenic agent, preferably a metabolic stimulating agent, more preferably a lipolytic agent, or a mixture thereof, the composition being either a topical composition for application to the selected area, or an area adjacent thereto, or an oral composition.