The present invention relates to an injectable composition for removing local fat comprising 300 to 600 IU of hyaluronidase and, based on the weight of the total composition, 0.08 to 0.4% by weight oflocal anesthetic, 0.01 to 0.02% by weight of antihistamine, 0.01 to 4.0% by weight of lipolysis stimulator, 0.01 to 0.08% by weight of the neurotransmitter, 0.01 to 4.0% by weight of the lipolytic agent, 0.05 to 0.3% by weight of reagent for pH adjustment and as allergies and acidosis treatment, and 0.1 to 2.0% by weight of collagen production stimulator, with the remainder being saline solution.According to the present invention, reduction in local fat tissues is promoted to ameliorate obesity and keep weight loss and a body shape. In addition, side effects or imbalance in skin can be prevented by evenly removing fat, and generation of collagen is promoted to give an effect of lifting where skin elasticity is kept.