The invention discloses a construction method for stopping water and reinforcing an end of a shield tunnel in the lithosphere. The method specifically comprises the steps of 1, preparing technological process; 2, clearing the specific construction requirements, namely, 1, layered arrangement of grouting holes, namely, arranging in plum blossom shape; 2, requirement on grouting, namely, grouting in every other holes; 3, conditions for stopping grouting, namely, the pressure exceeds 1.5 to 2 times that in design requirement, the grouted cement overflows from the hole or other places, and the grouting quantity exceeds the specified value; 4, determination of construction parameters; 5, construction of sealing the holes. The method has the beneficial effects that the end project of the shield tunnel can be constructed smoothly, the requirements on strength and impermeability are met, the construction period of the end of the shield tunnel is ensured, and the construction cost of the end of the shield tunnel is greatly decreased.