56 results about "Hindbrain" patented technology

Methods for expanding proliferating populations of neuronal subtype-specific progenitors are provided herein. In particular, the present invention provides methods for maintaining the unique gene profile and differentiation potential of neuronal subtype-specific progenitors, such as motor neuron progenitors and hindbrain serotonergic neural progenitors.

Methods for expanding proliferating populations of neuronal subtype-specific progenitors and creating substantially pure populations of motor neurons are provided herein. In particular, the present invention provides methods for maintaining the unique gene profile and differentiation potential of neuronal subtype-specific progenitors, such as motor neuron progenitors and hindbrain serotonergic neural progenitors.

The invention discloses a staggered massaging type cervical vertebra rehabilitation treatment device. The staggered massaging type cervical vertebra rehabilitation treatment device comprises an arc-shaped hollow plate, a belt wheel, a hollow column, massaging balls, a connecting rod, a driving device and a head back supporting device. The rehabilitation treatment device has the beneficial effects that a jacking bolt is screwed off and screwed on to adjust the height of a head back supporting plate, so that patients with different body forms can utilize the rehabilitation treatment device relatively comfortably; the connecting rod circularly moves up and down, so that the massaging balls can be used for carrying out hammering type massaging on necks of the patients when the massaging balls are located on the uppermost side; the massaging balls are used for massaging the necks of the patients in a staggered manner and the massaging efficiency is improved; three continuous U-shaped rotary rods are arranged, so that the necks of the patients can be massaged at a plurality of angles at the same time; in a massaging process, an electric heating rod is used for heating and medicine liquid injected into a medicine liquid cavity is heated; and medicine liquid gas at a certain temperature overflows through a gas medicine through hole, and medicines are applied to cervical vertebras of the patients, so that the cervical vertebra rehabilitation effect on the patients is relatively good.

Described herein are chemically defined, adherent culture protocols for generating functional motor neurons characteristic of diverse hindbrain and spinal cord regions, with high efficiency.

The invention discloses a manual cervical traction massager; a fixed outer support and an upper raised inner support are movably connected through rear ends; the front ends of the fixed outer support and the upper raised inner support are provided with adjustable inner and outer support fixing adhesive tapes; the parts of the fixed outer support which correspond to shoulders are provided with a left shoulder fixing vibration snap ring and a right shoulder fixing vibration snap ring; a left Fengchi vibration massage ball, a right Fengchi vibration massage ball and a rear Fengfu vibration massage ball are arranged on the upper raised inner support; and a Taiyin massage ball and a Taiyang massage ball are arranged on a forehead fixing strap. According to the manual cervical traction massager, the defect of the prior art that 60 percent of traction force is on the inferior maxilla when traction is carried out is overcome, the head serves as the origin of force, so that a fixing method in which the inferior maxilla is lifted is prevented, and the origin of force is located at the external occipital protuberance. Because the acupuncture points of the forehead, the hindbrain, the neck and the shoulders are positioned, when a user pinches by fingers, the Taiyin, Taiyang, Fengchi, Tianzhu, Fengfu, Jianjing and other acupuncture points of the neck, the shoulders and the head are tractioned and massaged by lifting the head and the hindbrain, so that diseases can be prevented and treated.

The invention provides a cervical vertebra rehabilitation robot. The cervical vertebra rehabilitation robot comprises a chest and back fixed support assembly; a chest and back support connection support frame installed on a top side of the chest and back fixed support assembly; a reduction motor assembly installed on one side of the chest and back support connection support frame; a neck adjustment fixing frame installed between the chest and back support connection support frame; a chin support frame installed at a bottom of one side of the neck adjustment fixing frame; and a back brain support frame installed on a top side of the neck adjustment fixing frame. The cervical vertebra rehabilitation robot has advantages of low cost, convenient carrying, strong adaptability, safety and reliability.

The invention discloses a sleeping pillow for relieving cervical vertebra pain. The sleeping pillow comprises a pillow body and a spring cavity formed in the pillow body; sponge located on the upper side of the spring cavity is fixedly arranged on the upper end wall of the pillow body; a spring plate capable of sliding up and down is arranged in the spring cavity in a spring connection mode; a supporting block extending into the sponge on the upper side of the spring cavity is fixedly arranged on the top wall of the spring plate; and the head of a user is rested on the sponge on the upper sideof the supporting block. According to the sleeping pillow for relieving cervical vertebra pain, when the user lies down and prepares to sleep, the neck of the user can be massaged after being placedin the massage area, and the cervical vertebra pain is relieved; the neck of the user can be automatically massaged by the pillow; the acupoints of the afterbrain of the user can bemassaged, so that people are helped to fall asleep quickly; when the pillow is used for massaging,the pain of cervical spondylosis can be relieved, and the aching feeling of the neck can be eliminated; and with a mechanical transmission mode adopted,the pillow is safe and reliable.

The invention discloses a zebra fish brain trauma model and a preparation method and application thereof. The preparation method of the zebra fish brain trauma model includes the steps that for an embryo in the 3dpf period, a needle is used for puncturing the hindbrain of a zebra fish, and microglial cells of the hindbrain of the zebra fish are labeled with fluorescent protein. After clinical first-line anti-inflammatory drugs are used for intervention, and more microglial cells can be activated to migrate and aggregate towards a wound part, so that injured hindbrain repairing is promoted; themicroglial-cell transgenic zebra fish brain trauma model can be used for rapid screening of drugs, so that an economical, convenient and reliable research model is provided for enterprise drug research and development and for evaluating the curative effect of the anti-inflammatory drugs in clinical brain trauma, encephalitis and other diseases, and the microglial-cell transgenic zebra fish braintrauma model has good application prospects and high application value.

The invention relates to a combined cervical vertebra pillow, the pillow comprises a front half pillow and a rear half pillow which are arranged front and back, the rear end surface of the front halfpillow is opposite to the front end surface of the rear half pillow; the front end surface of the front half pillow is a neck and shoulder supporting curved surface for supporting the neck and shoulders of a human body; the rear end surface of the rear half pillow is an afterbrain supporting curved surface for supporting the afterbrain of a human body; the front half pillow and the rear half pillow are connected through a distance adjusting piece. The distance between the front half pillow and the rear half pillow can be adjusted and limited by changing the position of the movable connection;therefore, the neck and shoulder supporting curved surface and the afterbrain supporting curved surface are matched to form neck placing surfaces with different widths; the pillow is simple in structure, convenient to use, low in cost, capable of meeting the requirements of different people and different cervical spondylosis conditions, capable of meeting the requirements of cervical vertebra patients for sufficient bending of the cervical vertebra or horizontal stretching of the cervical vertebra in the change of the conditions, and convenient to apply and popularize.

The present invention provides a method for producing a human cell aggregate containing a midbrain-hindbrain boundary neural progenitor tissue, including subjecting an aggregate of human pluripotent stem cells to suspension culturing in a serum-free medium containing insulin, and treating, in the suspension culturing, the aggregate of human pluripotent stem cells or a human cell aggregate derived therefrom with a ROCK inhibitor, a TGFβ signal inhibitor, and a first fibroblast growth factor. Furthermore, the human cell aggregate containing the midbrain-hindbrain boundary neural progenitor tissue is subjected to suspension culturing in a serum-free medium to induce formation of a neuroepithelial structure by neural progenitor in the neural progenitor tissue, whereby the human cell aggregate containing the cerebellar plate tissue can be obtained.

Methods for treating obesity or obesity related disorders are disclosed. These methods include the use of anti-obesity agents directed to the forebrain in combination with anti-obesity agents directed to the hindbrain.

The invention discloses an after-brain-surgery cranial nerve care device which comprises an inner layer protection cushion, a middle layer air bag, an outer layer cooling shell and a bottom fixing ring. The inner layer protection cushion comprises a frontal bone cushion, a parietal bone cushion, an occipital bone cushion, a temporal bone cushion and a sphenoid bone cushion which are fixedly connected with one another through locking and fixing devices. The cushions, the middle layer air bag and the outer layer cooling shell form a three-layer protection structure. Through the after-brain-surgery cranial nerve care device, by simulating a human brain skeleton structure, by means of the split type structural design, the product makes closer contact with the head, and the after-brain-surgerycranial nerve care device is convenient to detach and assembly; through the middle layer air bag, the after-brain-surgery cranial nerve care device can massage and protect the head bone through compression or depressurization in use; the inner layer protection cushion is made of silica gel and can make soft contact with the head, and therefore pressure sores are prevented, the brain tissue structure is protected, and the safety protection capacity of the product is improved.

The invention relates to the new application of the preparation of the Chinese traditional medicine, in particular to the prevention effect of blood-nourishing and brain-refreshing granules on the trauma of cerebral nerve cell. The test data indicate that the blood-nourishing and brain-refreshing granules have prevention effect on the trauma of the nerve cell of hindbrain cortex caused by ischemia-reperfusion of arteria cerebri media.

Methods for expanding proliferating populations of neuronal subtype-specific progenitors and creating substantially pure populations of motor neurons are provided herein. In particular, the present invention provides methods for maintaining the unique gene profile and differentiation potential of neuronal subtype-specific progenitors, such as motor neuron progenitors and hindbrain serotonergic neural progenitors.

Provided is a neck shoulder epencephalon tractor, wherein, rear ends of an upper tilting support and a lower tilting support are movably connected, front ends of the upper tilting support and the lower tilting support are provided with adjustable supports, the upper tilting support is provided with neck shoulder fixing snap rings at positions corresponding to the shoulders, and a head fixing part and a device for fixing and lifting epencephalon are arranged on the lower tilting support. The inventive tractor solves the problem that 60% of traction force acts on inferior maxilla in prior art. Due to adopting the head as the force acting point, the inventive tractor avoids the fixing manner of hooding inferior maxilla, and the force acting point of the inventive tractor locates at the external occipital protuberance of the epencephalon. The neck traction treatment is accomplished by the positioning of thauhiah, epencephalon, neck and shoulder and the hooding of head and epencephalon. The neck traction treatment fulfills aims of reducing the facet joint of cervical vertebra, unblocking the channles and collaterals, improving local blood circulation, regulating the nerves so as to treat the cervical spondylosis. The treatment using this tractor has no influence on normal movement of the inferior maxilla, that is to say, actions such as speaking, drinking water, biting and supping of the patient are not influenced.

The invention discloses a tooth-grinding-portion tongue-biting-prevention device composed of a fixed cap, a tooth plug and a locking device. The tooth-grinding-portion tongue-biting-prevention device is designed according to the tongue-biting conditions of an epilepsy and psychiatric patient. The fixed cap is provided with a plurality of binding belts according to the facial characteristics, the stability of the cap is improved, the length of a hindbrain lacing portion is adjusted according to the different head circumferences of the patient, and the experience comfort degree of the patient is increased. The tooth plug is designed according to the tooth shape of a human body, a plug body is partially placed into an oral cavity of the patient, and the situation that during onset of illness, the epilepsy and psychiatric patient bites a tongue is effectively prevented. Additionally, the tooth plug is connected with the locking device, a metal wire only reserves the length from the plug body to the locking device, and the situation that the plug body is spit out from the oral cavity by the patient is well avoided. The structure is simple, operation is easy, the workload of medical personnel is reduced, the work efficiency is improved, and the safety of the patient is better guaranteed.

Provided herein are methods of generating hindbrain cells, including respiratory hindbrain cells, from pluripotent stem cells. Also provided are methods of generating a three-dimensional organoid comprising a population of hindbrain cells including a heterogeneous population of interneurons.

The invention provides a positionable skull defect protection device, and belongs to the technical field of medical instruments. The device comprises an afterbrain fixing assembly, an afterbrain clamping sleeve assembly, an ear clamping assembly, a positioning protection assembly and a protection bag, and a main body structure is made of an elastic resin material; two groups of telescopic connecting sleeves capable of stretching out and drawing back automatically in the afterbrain clamping sleeve assembly are arranged in telescopic positions in the afterbrain fixing assembly in a bilateral symmetry mode, and the size can be adjusted according to the brain and the head of different sizes;rotatable ear clamping assemblies are arranged at the two ends of the telescopic connecting sleeve respectively, and the ear clamping assemblies can be clamped behind ears on the two sides of the head and can be rotationally adjusted according to different clamping sizes; a protection main sleeve in the positioning protection assembly is connected into the afterbrain fixing assembly from back to front, a plurality of groups of protection connecting sleeves can be connected into the protection main sleeve, each group of protection connecting sleeves can be provided with protection bags with different sizes, the protection bags can be positioned at corresponding positions according to different defect positions of the head, and the device has the advantages of being light in weight, convenient and fast to operate and good in air permeability.

The invention discloses a cooling head sleeve carrying a microfluid flow channel, which comprises a head sleeve body and a microfluid flow channel, and is characterized in that the head sleeve body is used for coating the head of a patient suffering from fever, the microfluid flow channel attached to the inner wall of the head sleeve body is carried in the head sleeve body, and the microfluid flow channel can be tightly attached to the afterbrain part of a human body and is used for cooling the head; wherein the microfluid flow channel has a special geometric structure, the special geometric structure is a flow channel designed on the basis of distribution of blood vessels and nerves at the afterbrain part, the flow channel bypasses a local sensitive area of the afterbrain, one side of the flow channel is provided with a microfluid flow channel inlet, the other side of the flow channel is provided with a microfluid flow channel outlet, and a cooling solution with high specific heat capacity is injected into the microfluid flow channel. Therefore, the efficient heat absorption and cooling effects are achieved. The cooling head sleeve carrying the microfluid flow channel has the advantages of being low in cost, easy to machine, good in cooling and heat absorption effect and the like, and can meet the use requirement for assisting in physical cooling of the head of a patient suffering from fever.

The invention relates to a medicament for treating scalp neuralgia. A preparation method comprises the following steps: using achyranthis root, Szechuan lovage rhizome, stiff silkworm, rhizoma gastrodiae, angelica dahurica and radix asteris as raw material drugs, adding water into the raw material drugs and decocting the mixture, condensing the decoction to be thick paste, drying and crushing the thick paste into medicinal powder, filling the medicinal powder into capsules, sterilizing and disinfecting the capsules to obtain the capsule preparation. The medicament for treating the scalp neuralgia has obvious effect, wherein for treating 210 cases of migraine, the effective rate is 94 percent; for treating 120 cases of forehead pain, the effective rate is 88 percent; for treating 185 cases of hindbrain pain, the effective rate is 92 percent; and the total effective rate is more than 90 percent.

The invention discloses a multifunctional bracket for a neurosurgery brain operation. The multifunctional bracket comprises a curvature-increasing and area-reducing type face supporting device, a head bearing automatic limiting device and a facial nerve reaction intraoperative detection auxiliary device. The invention belongs to the technical field of brain surgery supporting devices, and particularly relates to a multifunctional bracket for neurosurgery brain surgery. On the basis of guaranteeing the face supporting effect, the face supporting area is greatly reduced, the traditional supporting shape is changed, the side face of the face of a patient is supported by adopting the corrugated slight spiral plate, the supporting effect is guaranteed, the pressing area on facial nerves and muscles is reduced, and the difficulty of regulating and controlling expressions of the patient is greatly reduced; the weight of the head of a patient is fully utilized and converted into multi-direction clamping acting force for fixing the head, the design scheme of turning harm into benefit is achieved while traditional fixing equipment is reduced, and the technical problem that in the current afterbrain operation process of the patient, the front expression of the patient is difficult to observe is greatly solved.

The invention relates to the technical field of acupoint massagers, and discloses a method and device for autonomously searching for and massaging a Fengchi acupoint based on a PCL point cloud library, and the method comprises the following steps: obtaining a half d of the width of four fingers of a palm of a to-be-massaged person; wherein the rear part of a person lying or inline head leans against equipment, scans scanning the central axis of the rear head and identifying the lowest point of the central axis of the afterbrain; enabling the X-axis of equipment to move to the lowest point of the central axis of the afterbrain of the person, enabling the Y-axis to move by half of the width d of the four fingers of the palm in the left ear direction, and locating a scanning head of the equipment under the Fengchi acupoint vertical equipment and is the coordinate point of the Fengchi acupoint. The accurate position of the wind pool acupoint is calculated through point cloud surface curvature solving in the PCL point cloud library and a specified normal vector solving function, the defect that no equipment capable of accurately and autonomously searching the wind pool acupoint and massaging exists on the market at present is effectively overcome, the wind pool acupoint can be accurately positioned, the normal vector of the wind pool acupoint can be given. The massage head can directly massage the Fengchi acupoint by being perpendicular to local skin.

The invention discloses a cervical vertebra functional pillow. The pillow comprises a pillow body and is structurally characterized in that the pillow body comprises a head supporting area and a neck supporting area, and the head supporting area is provided with a convex after brain compression protrusion; the neck supporting area is sunken downwards and extends towards the side away from the head supporting area, and the height of the neck supporting area is gradually reduced; and side neck supporting areas are arranged on the two sides of the neck supporting area, the outer contours of the cross sections of the side neck supporting areas are composed of continuous arc sections and incline towards the side away from the head supporting area, and therefore shoulder contact faces inclining towards the side away from the head supporting area are formed on the surfaces of the side neck supporting areas. The pillow has the advantages that: enough support can be provided for the cervical vertebra, the space between the shoulders and the spine is fully filled, and therefore neck pain is prevented and relieved.

The invention discloses a multifunctional rehabilitation training device for orthopedics department. The device comprises a base, a pushing mechanism and a supporting plate, wherein a plurality of sliding ways with the same specification are installed at one end of a top of the base, the pushing mechanism is installed at tops of the sliding ways, the supporting plate is arranged at a top of the pushing mechanism and is movably connected with the pushing mechanism, a rotating mechanism is installed at one end of the supporting plate, and a traction mechanism is installed at the other end of the top of the base. A patient can drive a hand supporting plate with the feet to drive the hands of the patient to rotate, elbow joints of the patient move for rehabilitation training, medical staff do not need to control driving, the patient can directly feel whether the elbow joints are painful or not, the training device is not prone to faults and convenient to use, the afterbrain of the patient can be supported by controlling an afterbrain supporting column to ascend and descend, the jaw of the patient is lifted through the traction mechanism, the patient does not need to be raised by hands of a doctor, and manpower is greatly saved.

The invention discloses a calling device based on electrical brain information demodulation, which is to provide the calling device based on stable state visual induction electric potential demodulation for a ward calling system to substitute for a keypad type calling machine. The calling device consists of a service sign screen, an electrical brain collector, an electrical brain amplifier, an A / Dconverter and a calling extension machine; wherein the service sign screen is a LED display screen. The electric brain collector consists of 3-5 active electrodes, is fixed on the scalp on the position of occipital lobe of hind brain of a patient and is connected with the electric brain amplifier. Multi-lead electric brain signals are amplified by the electric brain amplifier and are transmittedto the A / D converter. The A / D converter transforms simulation signals into digital signals and transmits the digital signals to the calling extension machine. LED display control software and electricbrain processing and analyzing software are arranged on the calling extension machine. The LED display control software controls the display of the service sign screen. The electric brain processingand analyzing software processes and analyzes the electric brain data in real time and transmits calling information to a host machine. The invention can substitute non-contact and non-action type fixation operation for keypad type operation.

The invention provides a system for monitoring touch on a patient during operation of a dentist, which belongs to the technical field of medical instruments and is applied to a head model. The head model is provided with a face, cheekbones, a jaw frame, a maxilla, a mandible, cheeks, a jaw, an afterbrain, temples, a forehead and a skull, wherein touch sensors are fixedly arranged on the cheekbones, the forehead and the cheeks, touchness sensors are arranged on the afterbrain, the temples, the forehead and the skull; vector force sensors are fixedly arranged on the maxilla and the mandible respectively. The system also includes a computer, a signal processor and a binocular 3D camera which are electrically connected with the computer. The touch sensors, the touchness sensor and the vector force sensors are electrically connected with the signal processor respectively. The design in the invention can be used for teaching and examination; whether fulcrums of oral medical students in the practical operation process are correct or not is detected in real time, and the injury care awareness is improved. In final examination, various competitions and medical practitioner practice examination, the system assists or replaces judges to evaluate whether fulcrums of examinees are correct or not and whether the examinees have injury awareness or not.

The invention relates to an intelligent bionic head physiotherapy device based on neurology clinic, which comprises a fixing mechanism and a massage mechanism, the fixing mechanism is provided with the massage mechanism, and the fixing mechanism comprises a semi-arc block, a square long block, a connecting block, a compression spring, a rack plate, a fixing plate, a rotating rod, a first gear, a limiting frame, a massage frame and a moving frame. By arranging the fixing mechanism and the massage mechanism, the problem that the massage effect is reduced due to the fact that the pressing stimulation force generated by traditional medical staff during massage is not easy to control is solved, the head top can be massaged, the afterbrain and the temples can be massaged, and the massage effect is improved. The massage effect is good, and the massage range of the device during massage is greatly widened.

The invention discloses a cervical vertebra auxiliary treatment device for the pain department, relates to the technical field of medical treatment, and provides the following scheme that the cervical vertebra auxiliary treatment device comprises a front lower support, a first elastic band is fixed to the top of the front lower support, a front upper support is fixed to the top of the first elastic band, a rear lower support is arranged in the front lower support in a sleeved mode, and a second elastic band is fixed to the top of the rear lower support; a rear upper support is fixed to the top of the second elastic band, a recovery mechanism is rotationally connected to the interiors of the rear lower support and the rear upper support, a limiting mechanism and a connecting mechanism are fixed to the front lower support and the front upper support, a chin support is fixed to the top of the front upper support, and a back brain support is fixed to the top of the rear upper support. Different treatment and recovery means can be selected according to different postoperative periods of a patient, use is flexible, in the exercise period, the neck can be protected while exercise is met, the massage recovery function is achieved, and neck treatment and recovery are assisted.

The invention discloses a zebrafish brain trauma model, its preparation method and application. A method for preparing a zebrafish brain injury model. For embryos at the 3dpf stage, an empty needle is poked in the hindbrain of the zebrafish, and the microglial cells are labeled with fluorescent proteins. In the invention of this method, after the intervention of clinical first-line anti-inflammatory drugs, more microglial cells can be activated to migrate and gather to the wound site, thereby promoting the repair of the post-traumatic brain. The microglial cell transgenic zebrafish brain trauma model can It is used for rapid drug screening, which provides an economical, convenient and reliable research model for enterprise drug development and clinical efficacy evaluation of anti-inflammatory drugs in diseases such as brain trauma and encephalitis, and has good prospects and value.