44 results about "Dysfunctional uterine bleed" patented technology

The invention discloses a modified formulation and making method of present White Phoenix Bolus of Black-bone Chicken, which is characterized by the following: optimizing the formulation rate of each component to make new agent (particle, capsule and tablet); treating deficiency of both qi and blood, weak body, soreness and weakness of the loins and knees, inharmonious menses or metrorrhagia obviously; fitting for malfunctional intermenstrual flow and senile vaginitis with exactly effect; minimizing the intaking quantity with good taste; improving the biological utility without air-breathing and molding.

The invention discloses the application of astragalin in preparation of anti-ovarian-senescence medicaments. Astragalin can treat various ovarian failure diseases, and has a remarkable effect on polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovarian failure or climacteric syndrome and the like. According to the invention, astragalin is prepared into oral medicaments, percutaneous medicaments or parenteral medicaments for treating ovarian failure diseases.

The invention relates to an oral preparation of consolidating-yin decoction medicine, which is prepared with ginseng and other seven Chinese medicines mainly for treating yin deficiency and emission, turbid leucorrhea and dribbling and non-consolidation of menses resulted from deficiency, and the preparation method thereof. The oral preparation is prepared according to the conventional processes and utilizing the mixed extracts as raw materials, such as ginseng, old land, Chinese yam, cornus officinalis, dodder, milkwort, schisandra chinensis and baked licorice, together with vector or excipient which are utilized as matrix and acceptable in pharmacy. The preparation has the effects of reinforcing kidney and regulating menstruation, and mainly treats yin deficiency and frequent diarrhea, turbid leucorrhea and dribbling and non-consolidation of menses resulted from deficiency. The long-term clinical application of the prescription shows that the preparation has good effects on menoxenia, dysfunctional uterine bleeding, infertility, amenorrhea and nocturnal emission, etc.

A Chinese medicine for treating the metrorrhagia caused by functional disorder is prepared from 11 Chinese-medicinal materials including motherwort, Chinese angelica root, red peony root, red sage root, etc. Its preparing process is also disclosed.

The invention relates to C27 spirostane-type steroidal saponins isolated from Ypsilandra, Trillium and Paris and their preparation method, as well as their application in the preparation of drugs for treating hemorrhagic diseases, and application in the preparation of drugs for treating dysfunctional uterine bleeding, and the preparation of functional daily chemical products and health products. The materials used in a method of the invention are easy to obtain, the method is simple and easily operable, biological experiments of the compound produced show that the compound can induce platelet aggregation activity and hemostatic activity significantly.

The invention relates to a traditional Chinese medicine combination for treating gynaecological hemorrhagic disease, belongs to the traditional Chinese medicine field. The invention is characterized in that the traditional Chinese medicine combination is made from raw ingredients by weight parts as follows: Prepared Nutgrass Galingale Rhizome is 8 to 25 parts, typha orientalis stir-fried with vinegar is 5 to 20 parts, Myrrha Preparata is 8 to 20 parts, panpax notoginseng is 3 to 15 parts, stir-frying bitter orange is 8 to 20 parts, leonurus japonicus is 8 to 25 parts, and agrimony is 8 to 25 parts. The invention has the efficacies of thoroughfare regulating as well as hemostasia, and blood stasis and detoxication dissolving. The traditional Chinese medicine combination is mainly used for dysfunctional uterine bleeding, blood menostaxis, excess menstrual blood, postpartum lochiorrhea, the uterine bleeding caused by curettage, intrauterine device and induced labor, hysteromyoma, and vaginal bleeding caused by cervical erosion. The traditional Chinese medicine combination can achieve hemostasia purpose on various syndromes of deficiency complicated with excess.

The invention relates to a traditional Chinese medicinal composition preparation for treating dysfunctional uterine bleeding and a preparation method thereof. The preparation method comprises the following steps of: mixing and crushing the following components in parts by weight: 15-25 parts of Chinese angelica, 15-25 parts of red peony root, 10-20 parts of sanguisorba officinalis, 25-35 parts of hairyvein agrimonia herb and bud, 10-20 parts of cirsium japonicum, 10-20 parts of bletilla striata, 25-35 parts of cuttlebone, 10-20 parts of madder, 25-35 parts of raw rehmannia, 5-15 parts of liquorice, 6-10 parts of pseudo-ginseng, 10-15 parts of peony tree root bark, 25-35 parts of Chinese yam and 15-25 parts of bighead atractylodes rhizome; refluxing for 1-2 hours with 75 percent ethanol which is 5-6 times the volume of the crushed components; filtering to obtain filtrate, and repeatedly refluxing and extracting the residues for 2-3 times; mixing the filtrates and recycling the ethanol; uniformly mixing the filtrates and concentrating to dense extract of which the relative density at 80 DEG C is tested to be 1.21-1.25, thus obtaining ointment; moving the ointment into an oven, baking at 50-70 DEG C until the moisture content is lower than 5 percent; grinding to obtain medicinal powder. The traditional Chinese medicinal composition enables monarch, minister, assistant and guide to play respective effects, can quickly take effect, hardly causes side effects, can be applied both internally and externally and can treat both symptoms and root causes. The traditional Chinese medicinal composition can quickly inhibit development of diseases and remarkably shorten the course of diseases and is remarkable in treatment effect and worthy of popularization and application.

The invention discloses application of luteolin in preparation of ovarian senescence resistance medicines. The luteolin has obvious effects in treatment of multiple ovarian regression diseases such as polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovary failure or climacteric syndrome. The luteolin is prepared into oral medicines, transdermal delivery medicines or injection medicines for treating the ovarian regression diseases.

The invention discloses an application of oxyresveratrol in preparing an ovary aging resistant medicine. The oxyresveratrol has significant treatment effects on various ovary aging diseases such as polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovarian failure and climacteric syndrome. The oxyresveratrol is prepared into the oral, transdermal or injection medicine for treating the ovary aging diseases.

The invention discloses application of 5-hydroxymethylfurfural in the preparation of anti-ovarian senescence drugs. 5-Hydroxymethylfurfural can treat various ovarian failures significantly effectively, such as polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovarian failure or climacteric syndrome. The 5-hydroxymethylfurfural is made herein into oral drugs, transdermal drugs or injectable drugs for treating ovarian senescence.

The invention provides a composition used for treating dysfunctional uterine bleeding. The composition contains an active component and a pharmacologically acceptable carrier; the active component iscomposed of tortoise shell, raw rehmannia root, white peony root, raw cattail pollen, and ailanthus altissima bark at a weight ratio of 5-20:15-60:5-20:6-18:3-18. The invention also discloses a preparation method of the composition, and applications of the composition in treating of dysfunctional uterine bleeding.

The invention relates to a medicine for treating anovulatory dysfunctional uterine bleeding. Common symptom of anovulatory dysfunctional uterine bleeding is irregular metrorrhagia and is represented by irregular menstrual periods, unequal menstrual periods, indefinite or increased menstrual blood volume, and even excessive bleeding. No stomachache or other discomforts are available in the full bleeding period, secondary anemia always occurs when the amount of bleeding is great or the time is long, and excessive bleeding leads to shock. No abnormalities are found in general check-up and gynecologic examination, so that organic lesions of reproductive organ and general lesions are excluded. Ovulation is stopped through endometrium sample pathological examination, progesterone test in luteal phase and examination of basal body temperature. Through long-term research and clinical verification, the inventor finally finds a traditional Chinese medicine oral preparation for treating anovulatory dysfunctional uterine bleeding with better curative effect. The use level of medical components are found by the inventer, and the medicine comprises the components in parts by weight as follows: 10 parts of angelica sinensis, 10 parts of ligusticum wallichii, 10 parts of myrrh, 10 parts of trogopterus dung, 3 parts of pseudo-ginseng, 12 parts of the root bark of the peony tree, 10 parts of the root of red-rooted salvia, 6 parts of donkey-hide gelatin, 15 parts of fried folium artemisiae argyi, 20 parts of cuttle bone, 20 parts of keel and 15 parts of oyster. The medicines are combined, so that the medicines have the synergistic effect, and have the functions of promoting blood circulation to remove blood stasis, nourishing the blood and hemoslasis and regulating menstruation and relieving pain, so that the medicine can effectively treat anovulatory dysfunctional uterine bleeding.

The invention discloses a traditional Chinese preparation for curing dysfunctional uterine bleeding and a preparing method, and belongs to the traditional Chinese medicine field. The raw materials of the effective components of the traditional Chinese preparation comprise red-knees herb, citronella grass, melastoma dodecandrum, wilson begonia rhizome, curly bristlethistle herb, root of asiatic currant, lysimachia barystachys, mappianthus iodoies, phellinus, bergenin, dried ginger, purslane speedwell herb, woolly blue curls, centranthera grandiflora, panax notoginseng and viscid germander. According to the traditional Chinese preparation, the compatibility of medicines is good, the complement of the medicines is achieved, the functions of stasis dredging and dampness resolving, stagnate scattering and hemostasis, blood prompting and hemostasis, blood nourishing and enriching, heat clearing and dieresis promoting, nourishing and strong and spleen warming and cold dispelling are achieved, and the combination of the medicines can directly reach the diseased region. The advantages of being fast in effect, high in curing rate, free of toxic effect, and safe and convenient are provided for curing of the symptoms such as the dysmenorrhea, stomachache, concentration of the blood, malfunction of viscera, the bleeding tendency, bleeding after the post-menopause, the lutein cyst and the dimorphic temperature which are caused by the dysfunctional uterine bleeding. The traditional Chinese preparation has the advantages of being cheap in price, easy to prepare, and widely applicable to the clinic treatment of the dysfunctional uterine bleeding.

The invention provides a traditional Chinese medicine preparation for treating liver stagnation blood heat type dysfunctional uterine bleeding. The traditional Chinese medicine preparation comprises, by weight, the raw materials of 10-20 parts of gentians, 10-20 parts of radix paeoniae alba, 10-20 parts of fructus rubi, 10-20 parts of astragalus membranaceus, 10-20 parts of concha margaritiferallsta, 10-20 parts of scutellaria baicalensis, 10-20 parts of cyrtomium rhizome carbon, 10-20 parts of radix bupleuri, 10-20 parts of gardenias, 10-20 parts of rhizoma corydalis, 10-20 parts of herba leonuri, 10-20 parts of carbonized hair, 10-20 parts of angelica sinensis, 10-20 parts of trogopterus dung, 10-20 parts of cortex lycii radicis, 10-20 parts of dried radix rehmanniae, 10-20 parts of radix curcumae, 10-20 parts of glossy privet fruits, 10-20 parts of bighead atractylodes thizome, 10-20 parts of hairyvein agrimony, 10-20 parts of fried sanguisorba officinalis, 10-20 parts of caulis spatholobi and 10-20 parts of golden cypress. Liver stagnation blood heat type dysfunctional uterine bleeding is caused by emotional dissonance, liver depression of the fire, fire hyperactivity and blood moving, spleen health losing and the failure of the spleen to control circulating blood. The traditional Chinese medicine preparation removes heat from the liver so as to treat causes. The liver is soothed, the spleen is strengthened, blood is nourished, ying is harmonized, the menses is secured, flooding is avoided, and therefore symptoms are treated.

The invention relates to the field of medicine formulations, in particular to compound garden burnet and hairyvein agrimony soup for treating dysfunctional uterine bleeding (DUB), which is prepared from the following materials: garden burnet, hairyvein agrimony, clinopodium polycephalum, rehmannia glutinosa, dalbergia wood, cuttlebone, cattail pollen, rhizoma cyperi, angelica, fructus alpiniae oxyphyllae, eucommia, fructus schizandrae and cinnamon. The preparation method of the compound garden burnet and hairyvein agrimony soup comprises the steps of: dipping the thirteen parts of traditional Chinese medicines in water, decocting and then removing dregs to obtain filtrate, and putting the filtrate in an aseptic glass bottle for later use, and the soup is characterized in that the materials are as follows by weight percentage: 10-13 percent of the garden burnet, 9-12 percent of the hairyvein agrimony, 8-11 percent of the clinopodium polycephalum, 9-11 percent of the rehmannia glutinosa, 8-11 percent of the dalbergia wood, 5-7 percent of the cuttlebone, 4-6 percent of the cattail pollen, 5-7 percent of the rhizoma cyperi, 6-9 percent of the angelica, 5-7 percent of the fructus alpiniae oxyphyllae, 4-7 percent of the eucommia, 3-5 percent of the fructus schizandrae and 2-5 percent of the cinnamon. The invention has high curative effect of treating DUB without toxic and side effects and is applied to all kinds of uterine bleeding with and without the ovulatory period.

The invention discloses a medicine for treating dysfunctional uterine bleeding and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 28-32 parts of angelica sinensis, 12-16 parts of prepared rehmannia root, 12-16 parts of teasel root, 14-18 parts of white paeony root, 14-18 parts of Chinese yam, 14-18 parts of bighead atractylodes rhizome, 8-12 parts of carbonized sanguisorba root, 18-22 parts of radix angelicae, 4-8 parts of calcined oyster shell, 10-14 parts of cuttlebone, 3-5 parts of donkey-hide gelatin beads, 12-14 parts of carbonized hair and 8-12 parts of a garden cress extract. The medicine for treating dysfunctional uterine bleeding is prepared by taking natural Chinese herbal medicines as raw materials, is not added with any preservative or western medicine component, and has the effects of enriching blood and tonifying spleen, securing the essence and checking vaginal discharge and the like; moreover, the medicine provided by the invention is appropriate in compatibility of the various components, obvious in synergistic effect, fast in effect taking and safe, has a good effect of treating dysfunctional uterine bleeding and does not have any side effects.

The invention discloses a medicine for resisting inflammation, easing pain and stopping bleeding and a medicine active component screening method. The medicine comprises the following components: 300-500 parts of kaempferol, 1-5 parts of robinin, 8-20 parts of quercetin, 30-60 parts of baicalein and 10-20 parts of wogonin. The screening method comprises the following steps: screening active compounds from main chemical components in scutellaria baicalensis and sophora japonica; collecting a protein target of the active compound, retrieving and correcting to obtain a gene name, and establishinga dysfunctional uterine bleeding target set; obtaining an intersection gene of the active compound and a dysfunctional uterine bleeding target, carrying out pathway enrichment analysis on the intersection gene, and screening to obtain the active compound. The medicine is good in curative effect and can be more effectively used for resisting inflammation, easing pain and stopping bleeding.

Provided is a pharmaceutical composition for treating dysfunctional uterine bleeding, which contains an active ingredient and a pharmaceutically acceptable carrier. The ratio is 5‑20:15‑60:5‑20:6‑18:3‑18. The preparation method of the pharmaceutical composition and its application in the preparation of medicines for treating dysfunctional uterine bleeding are also disclosed.

The invention provides a medicine for treating adolescent dysfunctional uterine bleeding and a preparation method. The medicine comprises the following components in parts by weight: 1-3 parts of Chinese pulsatilla root, 1-3 parts of carbonized garden burnet root, 1-3 parts of carbonized rehmannia root and 1-3 parts of white sugar. The preparation method of the medicine comprises the following steps: selecting high-quality clean first-grade Chinese pulsatilla root, carbonized garden burnet root, carbonized rehmannia root and white sugar according to the ratio of the parts by weight, respectively removing impurities and dust in the components except white sugar, then putting the components in a cloth bag and tying the mouth of the cloth bag for later use; putting the medicines in pure water to be soaked for about 30 minutes until the medicine tissues are permeated, then putting the soaked medicines in a medicine decocting machine, injecting cold boiled water 30mm higher than the medicines to carry out first decoction for 35 minutes, leaching the medicine liquid, then re-injecting lukewarm boiled water to carry out second decoction for 25 minutes, mixing the decoctions and concentrating the mixed decoction into 1620ml of 50% traditional Chinese medicine liquid, then adding white sugar and mixing the materials uniformly, bagging and sealing the mixture to obtain a finished product of the traditional Chinese medicine liquid, and putting the finished product of the traditional Chinese medicine liquid in a refrigerator to be preserved for later use.

The present invention is directed to novel trisubstituted thiophene derivatives, pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these compounds are related to hormonal contraception, the treatment and / or prevention of secondary dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, uterine leiomyomata, endometriosis; polycystic ovary syndrome, carcinomas and adenocarcinomas of the endometrium, ovary, breast, colon or prostate. Additional uses of the invention include stimulation of food intake.

The invention discloses a traditional Chinese medicine decoction for treating functional uterine bleeding, which is prepared from the following raw materials: 10-15 grams of raw rehmannia, 8-12 grams of medlar, 8-12 grams of cornus, 8-12 grams of corydalis, 8 ‑12 grams of mugwort leaf charcoal, 20‑30 grams of calcined keel, 20‑30 grams of cuttlebone, 20‑30 grams of cypress leaves, 20‑30 grams of Imperata chinensis, 10‑15 grams of ecliptas, 10‑15 grams of rhizome charcoal , 5-10 grams of licorice. The traditional Chinese medicine decoction of the invention has the functions of nourishing yin and cooling blood, clearing away heat and solidifying blood, antibacterial and anti-inflammation, has quick effect in treating functional uterine bleeding, high cure rate, and is not easy to relapse.

The invention provides a composition for treating dysfunctional uterine bleeding. The composition is mainly prepared from, by weight, 4.5-9 parts of cornu cervi pantotrichum, 4.5-9 parts of herba ecliptae, 3-6 parts of rhizoma dioscoreae, 3-6 parts of apples, 3-6 parts of galla chinensis, 4.5-9 parts of sanchi, 0.9-1.5 parts of bombyx batryticatus, 9-30 parts of Japanese thistle herb roots, 9-12 parts of rhizoma cimicifugae, 6-12 parts of fructus ligustri lucidi, 6-12 parts of dried human placenta, 4-9 parts of radix paeoniae rubra, 3-12 parts of carapax et plastrum testudinis, 40-50 parts of honey and 200-400 parts of aromatic vinegar. The composition is remarkable in effect when used for treating dysfunctional uterine bleeding and functional uterine bleeding, has the bacteriostasis and haemostasis functions and can further thoroughly treat dysfunctional uterine bleeding from the root.

The invention discloses an application of hyperin in preparing an anti-ovarian-senescence drug. The hyperin can treat multiple ovarian senescence diseases, such as a polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovarian failure and a climacteric syndrome, and has a significant effect. According to the application, the hyperin is administrated orally, percutaneously or by injection for treating the ovarian senescence diseases.

A traditional Chinese medicine formula treating puberty dysfunctional uterine bleeding is characterized by comprising the following technological process: preparing the following compositions: 30 g of herba taxilli, 30 g of folium isatidis, 30 g of radix curcumae, 30 g of herba epimedii, 30 g of radix dipsaci, 30 g of semen cuscutae, 25 g of leaf sheath fibres of fortune windmillpalm, 25 g of fructus ligustri lucidi, 20 g of spica prunellae, 20 g of rhizoma curcumae, 20 g of herba leonuri, 20 g of caulis spatholobi, 18 g of pollen typhae, 18 g of flos chrysanthemi indici, 18 g of rhizoma anemarrhenae, 10 g of semen armeniacae amarum, 10 g of folium artemisiae argyi, 10 g of dwarf lilyturf tuber, 8 g of rhizoma dioscoreae, 8 g of fructus lycii, 8 g of common cephalanoplos herb, 5 g of radix platycodonis, and 5 g of fructus amomi. The traditional Chinese medicine formula solves the problems that a conventional traditional Chinese medicine formula treating puberty dysfunctional uterine bleeding is common in effect, long in responding time and large in side effect, and unreasonable drinking of the medicine easily causes menelipsis and presenility risks of adolescent girls. The traditional Chinese medicine formula disclosed by the invention is applicable to treat puberty dysfunctional uterine bleeding.

The invention relates to a traditional Chinese medicine combination for treating gynaecological hemorrhagic disease, belongs to the traditional Chinese medicine field. The invention is characterized in that the traditional Chinese medicine combination is made from raw ingredients by weight parts as follows: Prepared Nutgrass Galingale Rhizome is 8 to 25 parts, typha orientalis stir-fried with vinegar is 5 to 20 parts, Myrrha Preparata is 8 to 20 parts, panpax notoginseng is 3 to 15 parts, stir-frying bitter orange is 8 to 20 parts, leonurus japonicus is 8 to 25 parts, and agrimony is 8 to 25 parts. The invention has the efficacies of thoroughfare regulating as well as hemostasia, and blood stasis and detoxication dissolving. The traditional Chinese medicine combination is mainly used for dysfunctional uterine bleeding, blood menostaxis, excess menstrual blood, postpartum lochiorrhea, the uterine bleeding caused by curettage, intrauterine device and induced labor, hysteromyoma, and vaginal bleeding caused by cervical erosion. The traditional Chinese medicine combination can achieve hemostasia purpose on various syndromes of deficiency complicated with excess.

The invention provides a traditional Chinese medicine preparation for treating perimenopause type dysfunctional metrorrhagia. The traditional Chinese medicine preparation comprises, by weight, 10-20 parts of angelica sinensis, 10-20 parts of radix paeoniae alba, 10-20 parts of raspberry, 10-20 parts of astragalus membranaceus, 10-20 parts of herba epimedii, 10-20 parts of semen cuscutae, 10-20 parts of albizia flower, 10-20 parts of radix bupleuri, 10-20 parts of calcined oyster shell, 10-20 parts of corydalis tuber, 10-20 parts of leonurus, 10-20 parts of carbonized hair, 10-20 parts of codonopsis pilosula, 10-20 parts of trogopterus dung, 10-20 parts of poria cocos, 10-20 parts of rehmannia glutinosa, 10-20 parts of cyperus rotundus, 10-20 parts of glossy privet fruit, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of hairyvein agrimony, 10-20 parts of fried sanguisorba officinalis, 10-20 parts of caulis spatholobi and 10-20 parts of eclipta alba. The traditional Chinese medicine preparation is in accordance with the principle of treating both the manifestation and the root cause of the traditional Chinese medicine, the traditional Chinese medicine preparation deeply enters the focus to carry out treatment, on one hand, a large amount of estrogen is supplanted, blood is stopped and restrained, bleeding is stopped or relieved, and thus the dysfunctional metrorrhagia is put to an end from now on.

The invention discloses application of 5-hydroxymethylfurfural in the preparation of anti-ovarian senescence drugs. 5-Hydroxymethylfurfural can treat various ovarian failures significantly effectively, such as polycystic ovarian syndrome, dysfunctional uterine bleeding, premature ovarian failure or climacteric syndrome. The 5-hydroxymethylfurfural is made herein into oral drugs, transdermal drugs or injectable drugs for treating ovarian senescence.