Traditional Chinese medicine preparation for treating perimenopause type metrorrhagia and preparing method of traditional Chinese medicine preparation
A technology for traditional Chinese medicine preparations and uterine bleeding, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, and can solve problems such as inconsistent diagnosis and efficacy evaluation standards, and irregular TCM syndrome differentiation and classification.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 3
[0079] 2.1. Tested substance: Name: Pill of the present invention (obtained by the method of Example 3)
[0080] 2.2. Experimental animals: Class I big-eared white rabbits, 10, female, weighing 2.1-2.3 kg; provided by the Experimental Animal Center of the Department of Biology, Qingdao University School of Medicine;
[0081] 2.3. Test method:
[0082] 10 healthy rabbits with intact skin were selected, and 24 hours before the test, the hair on both sides of the back spine was cut off, and the hair removal area was about 4 cm × 4 cm on the left and right sides. During the test, take 0.2 ml of the test substance and apply it to a two-layer gauze of 2.5 cm × 2.5 cm, apply it to the surface of one side of the dehaired skin, cover it with oil paper, and fix it with adhesive tape. The skin on the other side served as a blank control. After 4 hours of sealing, the covering was removed, and the residual test substance was washed with warm water. The skin reaction at the application s...
Embodiment 4
[0091] Example 4: Skin Allergy Test Results
[0092] The tablet of the present invention was used to conduct induction and challenge contact tests, and the experimental mice were treated after 24 hours and 48 hours, and no skin erythema and edema were found, and there was no difference with the negative control group. The results showed that the tablet had nearly zero skin reaction intensity, that is, no skin allergy.
Embodiment 5
[0093] Example 5: Long-term toxicity test data
[0094]1. Experimental method
[0095] The guinea pigs were randomly divided into 4 groups of 15 animals each. Apply the depilatory agent evenly on both sides of the guinea pig's back spine so that the hair removal area is about 40 square centimeters. Wash the depilatory agent, after 24 hours of treatment, each group of guinea pigs is coated with 0.2, 0.4 and 0.8 ml of the suppository solution of the present invention, respectively, containing 92, 184 and 368 mg of crude drugs, and another group is coated with 0.8 ml of solvent twice a day for 30 consecutive days. The general condition of the guinea pigs was treated. After the experiment, the animals were sacrificed for hematological, blood biochemical and pathological examinations.
[0096] 2. Results
[0097] There were no local skin edema, congestion, erythema, bleeding spots and ulcers in the hair removal area of the trunk of the guinea pigs in the above three groups. T...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com