55 results about "Bio optical" patented technology

A bioptics bar code reader has first and second windows disposed at an angle to each other, a first imager for the first window and a second imager for the second window and first and second optics for directing light from a bar code in a reading area between the windows to the first and second imagers. The two imagers each obtain an image of the bar code in the reading area.

A particle detection system to identify and classify particles is programmed to capture digitized images of the particle generated by directing a light source through a fluid that includes the particle. The particle scatters the light and the scattered light is detected using a detector. The detector creates a digital signal corresponding to the particle, which is used by the system to generate a Bio-Optical Signature. This Bio-Optical Signature can then be used to classify the event, or particle. A count rate of the classified particles is monitored to detect a change that is representative of a toxin attack.

A bioptical laser scanning system employing a plurality of laser scanning stations about a two independently controlled rotating polygonal mirrors. The system has an ultra-compact construction, ideally suited for space-constrained retail scanning environments, and generates a 3-D omnidirectional laser scanning pattern between the bottom and side-scanning windows during system operation. The laser scanning pattern of the present invention comprises a complex of quasi-orthogonal laser scanning planes, including a plurality of substantially-vertical laser scanning planes for reading bar code symbols having bar code elements (i.e. ladder type bar code symbols) that are oriented substantially horizontal with respect to the bottom-scanning window, and a plurality of substantially-horizontal laser scanning planes for reading bar code symbols having bar code elements (i.e. picket-fence type bar code symbols) that are oriented substantially vertical with respect to the bottom-scanning window.

Bio-optical disc assays and bio-safety features for bio-optical drives to be applied on bio-optical discs and discs including same. Disc assays and means for performing disc assays while avoiding leakage of liquids loaded into discs. Related disc drive systems and methods include covering the disc ports with a sealant.

A method for forming a sensor is provided, together with a sensor formed according to the method. Photoresist material is deposited on a surface of the sensor, and is then patterned and etched to form an array of microlens structures. The structures are spaced close together in a predetermined pattern so that when a reflow process is performed, the structures melt and coalesce to form a barrier. The barrier defines a region for constraining or channeling the flow of reagent and analyte samples used in bio-optical sensors.

A particle detection system to identify and classify particles is programmed to capture digitized images of the particle generated by directing a light source through a fluid that includes the particle. The particle scatters the light and the scattered light is detected using a detector. The detector creates a digital signal corresponding to the particle, which is used by the system to generate Bio-Optical Signature. This Bio-Optical Signature can then be used to classify the event, or particle. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.

Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.

The invention provides an eutrophic lake total algae storage (token state: total chlorophyll a, dimension: t) remote sensing evaluation method comprising the steps that the quantitative relation between NDBI and concentration of water surface chlorophyll a is acquired based on bio-optical model simulation and actually measured data and popularized to MODIS satellite image data through Rayleigh scattering correction; the water depth spatial distribution situation of the Chaohu Lake is determined based on the water level of the Chaohu Zhongmiao Temple and the Chaohu brake of the same day and Chaohu underwater DEM; the lake NDBI threshold is judged through screening based on actually measured profile empirical data, and the evaluation method for total storage of algae in a unit water column under the algae bloom and non-algae bloom conditions is constructed; and the evaluation method for total storage of algae in a unit image element based on MODIS satellite images is constructed. The annular and monthly change rule of eutrophic lake total algae storage and spatial distribution thereof can be accurately acquired based on the method.

A bio-optical sensor has a surface provided with an array of sensing pixels and calibration pixels. The sensing and calibration pixels are arranged in an interleaved fashion. The sensing and calibration pixels may be interleaved 1:1, or they may be arranged in interleaved blocks. The image plane receives an analyte and a reagent that reacts with the analyte to produce light. The sensing pixels generate signals as a function of the light produced.

A particle detection system to identify and classify particles is programmed to capture digitized images of the particle generated by directing a light source through a fluid that includes the particle. The particle scatters the light and the scattered light is detected using a detector. The detector creates a digital signal corresponding to the particle, which is used by the system to generate Bio-Optical Signature. This Bio-Optical Signature can then be used to classify the event, or particle. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.

In an embodiment of the present disclosure, an optical method for determining morphological parameters and physiological properties of tissue is presented. The method includes using reflectance measurements from a tissue area for a plurality of wavelengths, using a bio-optical model, using radiative transfer modeling and using a non-linear inversion procedure. The method further includes systematically varying values of the morphological parameters and physiological properties of the tissue and simultaneously varying the inherent optical properties, which are linked to the morphological parameters and the physiological properties of the tissue, until the non-linear inversion procedure returns values for the morphological parameters and the physiological properties of the tissue such that an agreement between the reflectance measurements and reflectances computed by the radiative transfer model, based on the returned morphological parameters and the physiological properties of the tissue values and corresponding inherent optical properties values, reach a predetermined level of accuracy.

The invention provides a phytoplankton size structure analyzing method. The phytoplankton size structure analyzing method comprises the steps that after a seawater absorption spectrum is measured in situ, phytoplankton absorption spectrum contributions are extracted through a decomposition method, and information of the average grain diameter of algae and the size structure of phytoplankton is further extracted by adopting a bio-optical inversion algorithm. According to the method, in-situ high-frequency high-vertical-distinguishability measurement can be achieved, and the important significance on quickly finding out the size structure and spatial and temporal distribution of the phytoplankton biomass is achieved.

Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.

A sensor, such as a photoplethysmography sensor, for non-invasively monitoring a characteristic of an organism, such as a vital body sign. The sensor has multiple light sources disposed on a substrate and an array of optical probing channels for conveying light from the light sources to a probed region. Each detector pixel of an array of detector pixels receives light from a respective optical detection channel after interaction with a subregion of the probed region and spatial filtering, and generates a corresponding pixel signal. A processor derives a value of the vital body sign based at least upon the plurality of pixel signals

An embodiment of the invention provides a water color parameter inversion device and method for a near-shore estuary. According to the embodiment, a water bio-optical model is established through acquisition of remote sensing reflectance and water color parameters of the near-shore estuary, and the water bio-optical model is subjected to parameter optimization according to the acquired remote sensing reflectance and water color parameters; a near-shore estuary water color parameter inversion model of the water bio-optical model is established on the basis of a parameter optimization result of the water bio-optical model, water color parameter inversion of the near-shore estuary is realized, and an inversion result is obtained. With the adoption of the embodiment, the inversion precision of the water color parameters of the near-shore estuary can be improved.

A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.

A method for forming a sensor is provided, together with a sensor formed according to the method. Photoresist material is deposited on a surface of the sensor, and is then patterned and etched to form an array of microlens structures. The structures are spaced close together in a predetermined pattern so that when a reflow process is performed, the structures melt and coalesce to form a barrier. The barrier defines a region for constraining or channeling the flow of reagent and analyte samples used in bio-optical sensors.

The invention discloses an airborne marine laser radar signal processing method based on an iterative Klett. The method comprises the steps of processing a laser radar echo signal subjected to background noise removal and distance correction by using the Klett method, and obtaining different radar attenuation coefficients by setting different backscattering extinction logarithmic ratio k; substituting collected chlorophyll profile data into a bio-optical model to obtain the seawater attenuation coefficient; and comparing and analyzing an attenuation coefficient obtained by the bio-optical model at the same observation point and a radar attenuation coefficient obtained by inversion of laser radar, determining the seawater back scattering extinction logarithmic ratio k to further obtain a more accurate seawater attenuation coefficient. By adopting the method disclosed by the invention, the accuracy degree of the seawater attenuation coefficient profile obtained by inversion of laser radar can be improved.

A bioptical laser scanning system employing a plurality of laser scanning stations about a two independently controlled rotating polygonal mirrors. The system has an ultra-compact construction, ideally suited for space-constrained retail scanning environments, and generates a 3-D omnidirectional laser scanning pattern between the bottom and side-scanning windows during system operation. The laser scanning pattern of the present invention comprises plurality of groups of intersecting laser scanning planes that form a complex omni-directional 3-D laser scanning pattern within a 3-D scanning volume capable of scanning a bar code symbol located on the surface of an object presented within the 3-D scanning volume at any orientation and from any direction at the POS station so as to provide 360° of omnidirectional bar code symbol scanning coverage at the POS station.

An apparatus for detecting surface microcirculation of an acupoint includes an acupoint locator, a bio-optical blood flow detection device and a signal analysis processor. The acupoint locator includes an optical probe disposed therein and is configured to let the optical probe substantially align with and be in contact with a surface of the acupoint of a human subject. The bio-optical blood flow detection device is configured to capture microcirculation signals of the surface of the acupoint of the human subject by the optical probe. The signal analysis processor is configured to receive and analyze the microcirculation signals.

Disclosed is an apparatus and method for processing a bio optical signal based on a spread spectrum scheme including a demodulator configured to collect a bio optical signal generated in response to an incident beam modulated based on a spreading code being scattered from a target analyte, and remove a noise from the bio optical signal by demodulating the bio optical signal based on the spreading code, wherein the bio optical signal has a correlation with the modulated incident beam.

An apparatus for detecting surface microcirculation of an acupoint includes an acupoint locator, a bio-optical blood flow detection device and a signal analysis processor. The acupoint locator includes an optical probe disposed therein and is configured to let the optical probe substantially align with and be in contact with a surface of the acupoint of a human subject. The bio-optical blood flow detection device is configured to capture microcirculation signals of the surface of the acupoint of the human subject by the optical probe. The signal analysis processor is configured to receive and analyze the microcirculation signals.

A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.

The invention provides anelectro-magnetic principle-based bio-optical microscope with a convenient-to-clean lens and belongs to the technical field of biological cells. The electro-magnetic principle-based bio-optical microscope with the convenient-to-clean lens comprises an ocular lens; an operation box is fixedly connected to the bottom of the ocular lens; an electromagnet is fixedly installed in the operation box; a rotating shaft is movably connected to the interior of the operation box; and a telescopic rod is fixedly connected to the outer side of the rotating shaft. A transmission rod is moved, a conductive ball contacts with an electromagnet; the electromagnet is powered on to generate magnetism, a rotating wheel on the outer side of the electromagnet rotates, so that the telescopic rod is driven to rotate accordingly; a cam is driven to move through the cooperative use of the telescopic rod and a spring rod; a U-shaped clamp extrudes a water bag accordingly, and the effect ofconveniently cleaning the lens is achieved; a protective cover is driven to move through the cooperative use of a connecting ball and an extrusion rod, so that the effect of preventing clean water from splashing all around is achieved.

The invention discloses a lymphocyte bio-optical sensor based on a photo-fluidic capillary micro-cavity and a sensing method thereof. The sensor comprises a swept laser, a capillary micro-cavity-micro-nanofiber coupling unit, a photoelectric detector and a feedback control system, wherein the coupling unit is used for performing sensing test on a cell solution; the swept laser, the capillary micro-cavity-micro-nanofiber coupling unit, the photoelectric detector and the feedback control system are in coupled connection with one another by virtue of optical fiber fusion; the feedback control system is respectively and electrically connected with the photoelectric detector and the swept laser; the capillary micro-cavity-micro-nanofiber coupling unit is formed by vertically coupling micro-nanofibers and capillary micro-cavities mutually. According to the sensor in the invention, the capillary micro-cavity having tiny volume and high Q value serves as the lymphocyte sensing unit, and due tocontrol and interaction of light and micro-fluid in the micro-cavity, bio-optical lymphocyte sensing with advantages of being high in sensitivity, rapid in detection, label-free, compact in structure, high in integration level and low in cost is realized.

The invention belongs to the technical field of composite materials, and particularly discloses a bio-optical composite material, a preparation method and an application thereof. The bio-optical composite material comprises the following raw materials in parts by weight: 0.5-3 parts of mica, 0.5-2 parts of mirabilite, 0.5-3 parts of haematite, 0.5-1 part of gypsum, 0.5-1 part of magnetite, 0.5-3 parts of cinnabar, 0.5-2 parts of tourmaline, 0.5-3 parts of alum and 0.5-2 parts of medical stone. The raw material fine powder of the bio-optical composite material is evenly mixed in a high-speed mixer, and is irradiated for 12-24 hours by a laser with 457-600nm frequency band and a continuous output power of 400mW. The composite material can convert infrared waves emitted by human bodies to generate short-wave biological waves, can promote cell metabolism, improve cell pathology and improve cell physiology, has the functions of quickly relieving pain, repairing cell damage, dispelling glandhyperplasia, improving cell hypoxia, enhancing muscle fiber strength, strengthening physiological state of human organs and the like, can be used for medical treatment and human body rehabilitation health care, such as preparing multiple medical patches, eyeglass frames and other human body contact articles for daily use.

The invention discloses bio-optical simulation equipment which comprises a shell, a bio-optical simulation body, a peristaltic pump and a liquid storage bottle, wherein the bio-optical simulation bodyis arranged in a sample cell of the shell; the peristaltic pump is arranged in the shell; the liquid storage bottle is arranged in the shell; the liquid storage bottle, the bio-optical simulation body and the peristaltic pump are sequentially communicated to form a circulation loop by virtue of pipelines; and the peristaltic pump is used for driving liquid in the liquid storage bottle to circularly flow in the circulation loop. The bio-optical simulation equipment comprises the shell, and the bio-optical simulation body, the peristaltic pump and the liquid storage bottle are respectively arranged in the shell and communicated with one another to form the circulation loop, so that the optical, mechanical and blood oxygen flow properties of biological tissues can be simulated, and the equipment is conveniently carried by a user.

Provided are a measurement probe that is capable of determining whether a front end surface thereof is actually in contact with biological tissue, and a bio-optical measurement system. The measurement probe (3) comprises: an illumination fiber (31); a first light receiving fiber (32), a second light receiving fiber (33), and a third light receiving fiber (34) that receive returning illumination light; and a contact detection fiber (35) that detects contact between the front end surface of a rod lens (38) and biological tissue by receiving returning illumination light. The contact detection fiber (35) is disposed in a position at which the detection area of the contact detection fiber (35) on the front end surface of the rod lens (38), through which illumination light and returning light can pass, is outside the illumination area of the illumination fiber (31).