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40results about How to "Therapeutically effective" patented technology
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Modified nucleoside, nucleotide, and nucleic acid compositions
InactiveUS20130156849A1Therapeutically effectiveRaise hemoglobinOrganic active ingredientsPowder deliveryProtein precursorNucleotide
The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and / or activity.
Owner:MODERNA THERAPEUTICS INC
Block Copolymer Compositions and Uses Thereof
InactiveUS20080247987A1Therapeutically effectiveMuscular disorderOintment deliveryPolymer chemistryCopolymer composition
The present invention describes compositions, devices, and methods for the production, use and administration of the composition having a non-thermoreversible block copolymer composition.
Owner:ANGIOTECH INT AG (CH)
Biodegradable coating compositions including multiple layers
InactiveUS20060147491A1Avoiding toxic levelRate of releaseSurgeryCoatingsBiodegradable coatingBiomedical engineering
The invention provides devices for treatment of a patient, wherein at least a portion of the device is provided with a biodegradable coating composed of multiple coated layers of biodegradable material. The invention further provides methods of treatment utilizing the devices.
Owner:SURMODICS INC
Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
InactiveUS20040235712A1Therapeutically effectivePeptide/protein ingredientsGroup 8/9/10/18 element organic compoundsChemistryCoordination complex
Owner:MASSACHUSETTS INST OF TECH
Vectors and sequences for the treatment of diseases
The present invention provides new sequences, gene constructions, vectors and pharmaceutical compositions for the treatment of diseases and specially, for the treatment of mucopolysaccharidoses.
Owner:ESTEVE PHARMA SA +1
Method of treatment of neurological injury or cancer by administration of dichloroacetate
A method for treating neurological injury or cancer in a patient includes administration of a therapeutically-effective amount of dichloroacetic acid (DCA), a therapeutically-effective amount of electromagnetic radiation, or both to the patient.
Owner:STREETER JACKSON
Use of certain drugs for treating nerve root injury
The present invention relates to a method for treating nerve disorders in a mammal or a vertebrate by administering a TNF-alpha inhibitor. The invention also relates to the use of a TNF-alpha inhibitor in the preparation of pharmaceutical compositions for the treatment of nerve root injury and other nerve disorder.
Owner:SCIATICON
Recombinant Sendai virus
InactiveUS7101685B2Improve expression levelReduce distanceSsRNA viruses negative-senseSugar derivativesViral replicationGenetics manipulation
A method for generating Sendai virus particles by transfecting the Sendai virus genome to a host expressing all genes for the initial viral replication has been developed, enabling the genetic manipulation of Sendai virus and effective utilization of said virus as the vector.
Owner:DNAVEC RES
Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
InactiveUS7235259B2Improve aqueous concentrationEnhance solubilityPowder deliveryBiocideCholesteryl esterChemistry
A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
Owner:PFIZER INC +1
Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
InactiveUS7138520B2Therapeutically effectivePeptide/protein ingredientsGroup 8/9/10/18 element organic compoundsCoordination complexChemistry
Owner:MASSACHUSETTS INST OF TECH
Anti-angiogenic cellular agent for cancer therapy
InactiveUS20080260701A1Effective treatmentTherapeutically effectiveBiocideGenetic material ingredientsAbnormal tissue growthHematopoietic cell
The invention provides cytokine induced killer (CIK) cell populations and methods of using CIK cells to treat cellular proliferative disorders. CIK cells generated in vitro include both bulk cultures and clones. Individual CIK cell clones display distinct but overlapping lytic specificities for tumor cells and endothelial cells in vitro. When injected in vivo, bulk CIK cell cultures selectively attack tumor tissue. CIK cells can be used to treat a variety of cellular proliferative disorders, including early and late stage cancers as well as hematopoietic cell and solid tissue tumors.
Owner:HOPE ERNEST G
A 19-144, a2-73 and certain anticholinesterase inhibitor compositions and method for Anti-seizure therapy
ActiveUS20180177756A1Mitigation of impairmentTherapeutically effectiveNervous disorderOrganic chemistryMedicineAnticholinesterase Agents
This invention concerns a dosage form comprising a therapeutically effective amount of A19-144 or A2-73 and a therapeutically effective amount of at least one AED. This invention further encompasses a method of treating a subject in need of such treatment comprising administering a therapeutically effective amount of A19-144 or A2-73 in conjunction with an therapeutically effective amount of an AED.
Owner:ANAVEX LIFE SCI CORP
Functional Food Composition For Treating Allergy, Natural Tea Using the Same and the Manufacturing Method Thereof
InactiveUS20080311229A1Easy and regular administrationRapid therapeutic effectBiocidePre-extraction tea treatmentFunctional foodDisease
A functional food composition for treating allergy, comprising Saururus chinensis, Plantago asiatica, Poncirus trifoliata and Schisandra chinensis extracts, as active ingredients, a tea composition comprising the same and a manufacturing method thereof. The functional food and tea compositions for treatment of allergy in accordance with the present invention are therapeutically effective for any type of allergic diseases, irrespective of allergic causes. In particular, the tea composition advantageously enables easy and regular administration at need, which can achieve anti-allergic effects without particular efforts for treatment of diseases.
Owner:NAM JONG HYUN
Liposomal Formulations
InactiveUS20070224255A1Reduce adverse side effectsHigh encapsulation efficiencyAntiviralsPhosphorus organic compoundsDiseaseLiposome
Owner:ITALFARMACO SPA
Liposomal formulations
Owner:ITALFARMACO SPA
Vectors and sequences for the treatment of diseases
Owner:UNIV AUTONOMA DE BARCELONA +1
Novel GPCR and methods of use of the same
InactiveUS20090010909A1FunctionalFunction increaseOrganic active ingredientsNervous disorderCongestive heart failure chfIschemic Heart Diseases
The present invention relates to methods of identifying antagonists of GPR22, a G protein-coupled receptor (GPCR) and related compositions and methods. Antagonists of GPR22 are useful as therapeutic agents for the treatment of ischemic heart disease, including myocardial infarction, post-myocardial infarction remodeling, and congestive heart failure.
Owner:BURNHAM INST FOR MEDICAL RES
Plant extracts with Anti-diabetic and other useful activities
PendingUS20160022752A1Therapeutically effectiveRemarkable effectCompound screeningBiocideDiseaseInsulin-like growth factor
This invention relates to plant extracts containing nutritionally beneficial or medicinally active compounds. Some of these extracts, or the purified compounds contained therein, may be used for the nutritional support, prevention, treatment, or possible cure of various metabolic and other diseases and disorders in human beings and animals, including type 1 and type 2 diabetes, by regulating insulin signaling. This regulatory effect may include modulations of the levels and / or activity of the Insulin Receptor (IR), the Insulin-like Growth Factor (IGF) Receptor, and / or the Insulin Receptor Substrate (IRS) proteins in cells and tissues in the body.
Owner:HOUSEY PHARMA RES LAB L L C
Nucleic acid inhibitors of glutamate receptors
ActiveUS20060148746A1Therapeutically effectiveInhibitionNervous disorderSugar derivativesDiseaseMetabotropic glutamate receptor 4
The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors.
Owner:THE RES FOUND OF STATE UNIV OF NEW YORK +1
Compositions and methods involving the combination of a thromboxane A2 receptor antagonist and an inhibitor of cyclooxygenase-2
InactiveUS20050020657A1Reduce severityShorten the durationBiocideNervous disorderThromboxane A2 receptorCyclooxygenase
The invention is directed to methods and compositions that can be used in the treatment of inflammation, pain and cardiovascular disorders. Methods and compositions are described involving the combination of a thromboxane A2 receptor antagonist and an inhibitor specific for cyclooxygenase-2.
Owner:B M R A CORP
Pharmaceutical Compositions of Cholesteryl Ester Transfer Protein Inhibitor
InactiveUS20060211654A1Increase concentrationImprove solubilityAntibacterial agentsPowder deliveryCholesterylester transfer proteinCholesteryl ester
A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
Owner:BEND RES
Methods, compositions, and kits for predicting the effect of compounds on hot flash symptoms
InactiveUS20050064462A1Prevent and treat osteoporosisAvoid symptomsBiocideMicrobiological testing/measurementHot flashMedicine
The present invention provides methods, compositions, and kits, for determining the effects of one or more candidate compounds on hot flash symptoms. In certain aspects, the methods, compositions, and kits can be used to identify compounds that decrease the incidence of hot flash symptoms. In other aspects, the methods, compositions, and kits can be used to determine whether candidate compounds increase the incidence of undesirable hot flash symptoms when administered to a subject.
Owner:SIGNAL PHARM INC
Skin care composition
InactiveUS20180325973A1Therapeutically effectiveCosmetic preparationsToilet preparationsAtopic dermatitisAD - Atopic dermatitis
The present invention relates to skin care compositions comprising extract or juice from the plant Kalanchoe daigremontiana for topical administration to human skin and methods of making said compositions. The compositions are therapeutically effective for hydrating and conditioning the skin and are shown to be clinically effective at treating dermal conditions or skin disorders, in particular, psoriasis, atopic dermatitis or allergic contact dermatitis.
Owner:ISN PHARMA SP ZOO
Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain
InactiveUS6846826B2Maintain hypotensionInducing effectBiocideOrganic chemistryPhenylpiperazineHalogen
Certain 1,4-dihydropyridine compounds, useful as adrenergic blocking agents and as calcium channel blocking agents, the compounds having the formula wherein R1 is hydrogen, halogen, C1-6-alkyl, or C1-6-alkoxy, R3 is hydrogen, halogen, C1-6-alkyl, C1-6-alkoxy, or CF3(CH2)nO— wherein n is 1, 2, or 3, and R5 is —NHCH2CH2O— or —N(CH2CH2)2N—.
Owner:LIN TONG HO +1
Skin care composition
InactiveUS20200030398A1Therapeutically effectiveCosmetic preparationsAerosol deliveryPharmacologyPsoriasis universalis
Owner:ISN PHARMA SP ZOO
N-lipoic-amino acid or peptide, derivatives and their uses
ActiveUS20190161467A1Therapeutically effectiveReduce impactCosmetic preparationsPeptide/protein ingredientsAmino acidPeptide
Novel compounds of N-Lipoic-amino acid, N-Lipoic-peptides and their derivatives are described. Also described are compositions and method of compositions containing the derivatives of the amino acids or peptides, and their uses including treating and preventing dermatological or cosmetic conditions or other disorders of the cutaneous system. Compositions and methods of using the compositions for skin lightening and cosmetics are also disclosed.
Owner:NEOSTRATA
Novel NANO gold and process for preparation
InactiveUS20140234439A1Non toxicSmall particle sizeHeavy metal active ingredientsMaterial nanotechnologyFerulaGranularity
This invention relates to bio synthesis of novel nano gold through environment friendly process with the aid of plant materials classified under the taxonomical genus Dalbergia, Citrus, Ferula and Dolichos or Macrotyloma. The present inventive product novel nano gold finds utility in, the treatment of humans and animals, nutraceutical, cosmeceutical and herbal composition, the field of technology including but not limited to nano technology, green technology and bio technology. The invention also relates to the use of plant materials in the purification and particle size reduction of metals.
Owner:BENDALE YOH N +1
Hiv-1 neutralizing antibodies and uses thereof
ActiveUS20180256719A1Therapeutically effectiveAntiviralsAntibody ingredientsAntibodyNeutralizing antibody
Owner:DUKE UNIV +1
N-lipoic-amino acid or peptide, derivatives and their uses
PendingUS20220127242A1Therapeutically effectiveReduce impactCosmetic preparationsOrganic chemistryPeptideMolecular biology
Owner:NEOSTRATA
Functional food composition for treating allergy, natural tea using the same and the manufacturing method thereof
InactiveUS7862839B2Easy to manageTherapeutically effectiveBiocidePre-extraction tea treatmentDiseasePlantago asiatica
A functional food composition for treating allergy, comprising Saururus chinensis, Plantago asiatica, Poncirus trifoliata and Schisandra chinensis extracts, as active ingredients, a tea composition comprising the same and a manufacturing method thereof. The functional food and tea compositions for treatment of allergy in accordance with the present invention are therapeutically effective for any type of allergic diseases, irrespective of allergic causes. In particular, the tea composition advantageously enables easy and regular administration at need, which can achieve anti-allergic effects without particular efforts for treatment of diseases.
Owner:NAM JONG HYUN
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