30results about How to "Slows introduction" patented technology

A spreader insert for use with a surgical retractor is provided. The spreader insert includes a circular head with two or more downwardly extending blades. One end of each blade of the insert is rotatably fastened to the head of the insert, such that each blade can be tilted inwardly or extended outwardly from a central axis of the device. Suitable fasteners are provided to rotate the blades from a closed position in which the distal ends of the blades are almost touching each other in order to improve ease of introduction into the surgical field. In an open position, the blades rotate outwardly to hold body tissue in place. Alternatively, the entire spreader insert is machined from a hardenable steel tube, the blades of which are formed so that, when released, they spring outwardly to an open position.

Method for providing a subscription to an IP-based Multimedia Subsystem (IMS) for a first client of a packet-switched network is provided. The first client is identified by the same MSISDN number as a second, mobile client of a circuit-switched network. The method comprises the following steps: a) sending, by the first client, a register request to an IMS Server via the packet-switched network, b) sending, by the IMS server, a location query request to a register for the IMS user identities (HSS), c) requesting, by the register for the IMS user identities (HSS), the user subscription information of the circuit-switched network from the register for the circuit-switched network (HLR), d) sending, by the register for the circuit-switched network (HLR), to the register for the IMS user identities, the user subscription information of the second client, e) creating, by the register for the IMS user identities (HSS), a user IMS subscription information based on user subscription information of the second client.

A deep channel type of radial ball bearing having a retainer. The bearing has an outer ring and an inner ring. Running channels are formed on the mutually opposing orbiting surfaces of the outer ring and inner ring. A specified number of balls are fit into the running channels. The retainer having pockets is placed between the outer ring and the inner ring. Each ball is captured in one of the pockets. A ball contact surface is formed on the inner surface of each edge on the opening side of the pockets. A curved ridge line forms the boundary between the inner surface of the pocket and the contact surface. This curved ridge line that forms the boundary is substantially parallel to the direction of rotation of the balls. A channel is formed at the bottom surface of the pocket. The channel extends from the inner perimeter to the outer perimeter of the retainer. The lubricating oil on the bottom surface of the pocket flows through the channel by virtue of the rolling of the balls and is guided to the outer perimeter side. A triangle-shaped fin having an inclined surface is integrally formed between the adjacent pockets on the outer perimeter surface. The inclined surface is formed on the trailing side of pocket with respect to the retainer direction of rotation. Lubricating oil directed from the above-described channel to the outer perimeter surface by the rolling of the ball is received at the inclined surface of the fin and is supplied to the vicinity of the leading edge of the pocket that is located behind the fin by the rotation of the retainer.

A method is provided for inducing or enhancing an immune response in a mammal to a target polypeptide expressed in a plurality of cells of the mammal, which method comprises administering to the mammal an inhibitory nucleic acid which targets a region of a ribonucleic acid (RNA) which encodes said polypeptide. Also provided is a pharmaceutical composition comprising an inhibitory nucleic acid which targets a region of an RNA which encodes a target polypeptide expressed in a plurality of cells of a mammal, such that translation of an aberrant form of the target polypeptide occurs in said cells, said truncated form of the target polypeptide comprising one or more T cell epitopes; together with a pharmaceutically acceptable carrier or diluent.

The present disclosure relates to 2-dimensional MXenes surface-modified with catechol derivatives, a method for preparing the same, MXene organic ink including the same, and use thereof (e.g. flexible electrodes, conducive cohesive/adhesive materials, electromagnetic wave-shielding materials, flexible heaters, sensors, energy storage devices). Particularly, the simple, fast, and scalable surface-functionalization process of MXenes using catechol derivatives (e.g. ADOPA) organic ligands significantly improves the dispersion stability in various organic solvents (including ethanol, isopropyl alcohol, acetone and acetonitrile) and produces highly concentrated organic liquid crystals of various MXenes (including Ti₂CT_x, Nb₂CT_x, V₂CT_x, Mo₂CT_x, Ti₃C₂T_x, Ti₃CNT_x, Mo₂TiC₂T_x, and Mo₂Ti₂C₃T_x). Such products offer excellent electrical conductivity, improved oxidation stability, excellent coating and adhesion abilities to various hydrophobic substrates, and composite processability with hydrophobic polymers. This finding will lead to further studies on the structures, properties, and physics of the organic MXene liquid crystals and their practical applications.

For a simplified method for heating a pre-warmed muffle used for dental ceramics in a dental furnace, wherein a saving of time in heating before the pressing and also a parallel heating of the muffles should be made possible, the following steps are suggested: a) heating of the muffle to a maximal temperature (T_max), which is above the pressing temperature (T_press), in which pressing is carried out, b) possibly keeping the muffle at a maximal temperature (T_max) during a first pause (t-₁), c) cooling of the muffle to a minimal temperature (T_min), which is at most as high as the pressing temperature (T_press), and d) keeping the muffle at a minimal temperature (T_min) during a second pause (t2). In addition, a corresponding control device for the dental furnace and a furnace equipped with this kind of control device are produced.

With reference to FIG. 1A, the present invention provides a two-stroke internal combustion engine comprising: a piston (19) reciprocable within a cylinder (20); an exhaust port (23) allowing communication of the cylinder (20) with an exhaust passage (24), which port (23) is opened and closed by the piston during the reciprocal motion thereof; moveable shutter means (1) for varying the effective area of the exhaust port (23), which shutter means (1) varies the effective area cyclically in a timed relationship to the reciprocal motion of the piston (19) within the cylinder (20); a compression ratio variation mechanism (41) additional to and separate from the moveable shutter means (1) for varying a compression ratio of the cylinder (20); sensor means (12, 14, 34) for measuring one or more operating characteristics of the engine and for generating signals corresponding thereto; and a control unit (11) which processes the signals generated by the sensor means (12, 14, 34) and controls the motion of the shutter means (1) accordingly and control the effective area of the exhaust port (25) and controls the compression ratio variation mechanism (41) to independently vary the compression ratio of the cylinder (20).

Disclosed are O-protected compounds of the formula (I): wherein B is an optionally protected nucleobase, and R¹-R³ are as described herein, a method of preparing such compounds, and a method of preparing oligonucleotides such as RNA starting from such compounds. The O-protected compounds have one or more advantages, for example, the 2′-O-protected compound is stable during the various reaction steps involved in oligonucleotide synthesis; the protecting group can be easily removed after the synthesis of the oligonucleotide, for example, by reaction with tetrabutylammonium fluoride; and/or the O-protected groups do not generate DNA/RNA alkylating side products, which have been reported during removal of 2′-O-(2-cyanoethyl)oxymethyl or 2′-O-[2-(4-tolylsulfonyl)ethoxymethyl groups under similar conditions.

A device (30) for strengthening a card reader (10) including a slot (12) at least partly delimited by a base (34) and two lateral walls (17) and extending along a longitudinal direction, the slot being intended to receive a card moving along the longitudinal direction while bearing on the base, the device including a wire (30) of substantially circular cross-section arranged at the level of the base and on which the card is intended to slide.