39results about How to "Reduce and prevent adhesion" patented technology

A protein obtainable from a non pathgenic microorgansim, said protein having mucosa binding promoting activity and a molecular weight of 20-40 kD is disclosed. Application of such a protein or a peptide derived therefrom in a method of screening non pathogenic microorganisms for a microorganism capable of specifically binding mucosa, said method comprising detection in a manner known per se of the presence of a particular protein on or in a microorganism or in a culture of microorganisms, said particular protein being the already defined protein. Kits suitable for such a screening method are also disclosed. Use of a component selected from the group of components comprising a protein or peptide as defined; an expression vector comprising nucleic acid encoding such protein or peptide; a recombinant microorganism or a part of said microorganism expressing such protein or peptide, said part expressing mucosa binding promoting activity; a non pathogenic microorganism capable of expressing such protein or peptide or a part of said microorganism, said part expressing mucosa binding promoting activity as pharmaceutically active component in a pharmaceutical composition for prophylaxis and / or treatment of disease or illness associated with a mucosa colonizing pathogenic microorganism. Use of such components as food additive and compositions comprising such components are described.

A protein obtainable from a non pathogenic microorganism, said protein having mucosa binding promoting activity and a molecular weight of 20-40 kD is disclosed. Application of such a protein or a peptide derived therefrom in a method of screening non pathogenic microorganisms for a microorganism capable of specifically binding mucosa, said method comprising detection in a manner known per se of the presence of a particular protein on or in a microorganism or in a culture of microorganisms, said particular protein being the already defined protein. Kits suitable for such a screening method are also disclosed. Use of a component selected from the group of components comprising a protein or peptide as defined an expression vector comprising nucleic acid encoding such protein or peptide a recombinant microorganism or a part of said microorganism expressing such protein or peptide, said part expressing mucosa binding promoting activity a non pathogenic microorganism capable of expressing such protein or peptide or a part of said microorganism, said part expressing mucosa binding promoting activity as pharmaceutically active component in a pharmaceutical composition for prophylaxis and / or treatment of disease or illness associated with a mucosa colonising pathogenic microorganism. Use of such components as food additive and compositions comprising such components are described.

A protein obtainable from a non pathgenic microorgansim, said protein having mucosa binding promoting activity and a molecular weight of 20-40 kD is disclosed. Application of such a protein or a peptide derived therefrom in a method of screening non pathogenic microorganisms for a microorganism capable of specifically binding mucosa, said method comprising detection in a manner known per se of the presence of a particular protein on or in a microorganism or in a culture of microorganisms, said particular protein being the already defined protein. Kits suitable for such a screening method are also disclosed. Use of a component selected from the group of components comprising a protein or peptide as defined; an expression vector comprising nucleic acid encoding such protein or peptide; a recombinant microorganism or a part of said microorganism expressing such protein or peptide, said part expressing mucosa binding promoting activity; a non pathogenic microorganism capable of expressing such protein or peptide or a part of said microorganism, said part expressing mucosa binding promoting activity as pharmaceutically active component in a pharmaceutical composition for prophylaxis and / or treatment of disease or illness associated with a mucosa colonizing pathogenic microorganism. Use of such components as food additive and compositions comprising such components are described.

A coating composition is provided for obtaining a hydrophobic, antimicrobial product, particularly fiberglass products, wherein the coating composition contains a compound having at least one hydrophobic group and at least one group capable of interacting with a group on the surface of the product substrate, particularly with Si or OH groups on the glass fibers of the fiberglass product, and the coated products obtained thereby.

Methods for the prevention of adhesion formation involve the administration of therapeutic formulations to a patient which include antibodies to TIMP-1 or TIMP-1 antisense oligonucleotides. The formulations can also include suitable carriers, such as a hyaluronic acid matrix, for optimal administration. The treatment procedure can be initiated and monitored by a diagnostic procedure which involves the detection of elevated levels of TIMP-1 in a patient.

The invention provides a responsive polymeric system, comprising: a polymeric responsive component capable of undergoing a transition that results in a sharp increase in viscosity in response to a change in temperature at a predetermined body site; wherein the polymeric component comprises hydrophilic and hydrophobic segments covalently bound within the polymer component, by at least one chain extender or coupling agent, having at least 2 functional groups; wherein the hydrophilic and hydrophobic segments do not display Reverse Thermal Gelation behavior of their own at clinically relevant temperatures and; wherein the viscosity of the polymeric component increases by at least about 2 times upon exposure to a predetermined trigger.

The invention provides a responsive polymeric system, comprising: a polymeric responsive component capable of undergoing a transition that results in a sharp increase in viscosity in response to a change in temperature at a predetermined body site; wherein the polymeric component comprises hydrophilic and hydrophobic segments covalently bound within the polymer component, by at least one chain extender or coupling agent, having at least 2 functional groups; wherein the hydrophilic and hydrophobic segments do not display Reverse Thermal Gelation behavior of their own at clinically relevant temperatures and; wherein the viscosity of the polymeric component increases by at least about 2 times upon exposure to a predetermined trigger.

Connexin modulation for the treatment of surgical adhesions, and associated methods, compositions, and articles.

An ink jet recording apparatus has a first discharge port array in which discharge ports of a plurality of nozzles which discharge an ink composition containing an inorganic pigment are disposed side by side, a second discharge port array in which discharge ports of a plurality of nozzles which discharge an ink composition containing a coloring material other than the inorganic pigment are disposed side by side, a nozzle plate having the first discharge port array and the second discharge port array, a liquid repellent film provided on the nozzle plate, a wiping member which wipes the surface of the nozzle plate and has absorbability of the ink composition, in which, in a series of operations in which the surface of the nozzle plate is wiped by the wiping member, the second discharge port array is wiped in priority to the first discharge port array.

An engine block coating system for applying a coating to an engine block includes a work stand, a coating gun, and a first nozzle. The work stand supports the engine block. The coating gun discharges coating on an inner surface of a first cylinder bank. The first nozzle discharges gas from a second cylinder bank to a crankcase side of the first cylinder bank and the second cylinder bank such that the second cylinder bank is shielded from the coating. The coating gun and the first nozzle are arranged relative to each other such that gas discharged by the first nozzle is discharged toward the coating to alter a direction of the coating by the gas discharged by the first nozzle directly contacting the coating such that the coating would otherwise contact the cylinder bore of the second cylinder bank upon stopping discharge of the gas by the first nozzle.

A composition comprising an extract from an aquatic organism is disclosed. The composition is capable of preventing adhesion of a cell to a surface and is devoid of cytotoxic or cytostatic activity. Medical devices comprising same and methods for preventing or treating a pathological infection using same are also disclosed.

A three-dimensional printing apparatus includes a printing table, a line head, a conveyor, an air supplier, and a controller. The line head includes discharge holes disposed in a straight line in a first direction intersecting a scanning direction. The air supplier supplies air to a lower surface of the line head in a second direction intersecting the first direction such that the air is supplied from a rear side to a front side in the scanning direction when the line head moves relative to the printing table while discharging a curing liquid.

Intraperitoneal administration of glutamine reduces post-operative adhesion formation.

A high contrast photographic material is disclosed containing a new type of hydrazine compound characterized in that said hydrazine compound comprises a redox moiety capable of developing an exposed silver halide crystal. Preferably the photographic material is a graphic arts material for pre-press applications. The developed photographic material shows high gradation, and excellent dot quality and exposure latitude.

The present invention relates to a non-curable coating composition which is used for preventing adhesion of various sticky substances to the surfaces of substrates. The non-curable coating composition contains a carboxy-modified silicone represented by the following general formula (1) and an epoxy / oxyalkylene-modified silicone represented by the following general formula (2) in a weight ratio ranging from 1:2 to 1:30, and further comprising an oxyalkylene-modified silicone having an HLB of 10 or more, represented by the following general formula (3): R3SiO (R2SiO)m(RASiO)nSiR3 (1) R3<sub2>—< / sub2>pXpSiO (R2SiO)x(RX—SiO)y(RYSiO)zSiXqR3<sub2>—< / sub2>q (2) R3—pYpSiO (R2SiO)a(RYSiO)bSiYqR3-q (3) wherein each R═C1<sub2>—6 < / sub2>alkyl; A=carboxy-containing group; m=0 to 1,000; n=2 to 100; X=epoxy-containing group; Y=oxyethylene-containing group; p=0 to 1; q=0 to 1; x=0 to 500; y=1 to 100; z=1 to 300; a=0 to 100; b=0 to 50; and p+q+b=1 or more.

An aqueous or water-borne precursor for forming an anti-fouling heterophasic thermoset polymeric coating is provided. The precursor includes a fluorine-containing polyol precursor having a functionality >about 2 that forms a branched fluorine-containing polymer component defining a continuous phase in the anti-fouling heterophasic thermoset polymeric coating. The precursor also includes a fluorine-free precursor that forms a fluorine-free component present as a plurality of domains each having an average size of ≥about 100 nm to ≤about 5,000 nm defining a discrete phase within the continuous phase in the anti-fouling heterophasic thermoset polymeric coating. A crosslinking agent and water are also present. An emulsifier may also be included. Methods of making anti-fouling heterophasic thermoset polymeric coatings with such precursors are also provided.

A non-curable coating composition which uses a modified silicone having a functional group and can effectively prevent or reduce adhesion of sticky contamination substances to the surface of a substrate is provided. The non-curable coating composition contains a carboxy-modified silicone having carboxy-containing groups at side chains, and an epoxy / oxyalkylene-modified silicone having an epoxy-containing group and an oxyethylene-containing group at side chains, in a weight ratio ranging from 1:2 to 1:30.

The present disclosure relates to the use of a composition for reducing or preventing colloids adhesion and / or fouling on a substrate, the composition comprising a copolymer having repeating units derived from one or more zwitterionic monomers and repeating units derived from one or more phosphorous acid monomers.

The present disclosure relates to a method for reducing or preventing colloids adhesion and / or fouling on a substrate in need thereof by forming a coating having a first layer that includes a polyphenol compound, and a second layer that includes a hydrophilic polymer having repeating units derived from one or more zwitterionic monomers, typically one or more betaine monomers, on the substrate. The present disclosure also relates to the coating made thereby and an article having the said coating.