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35results about How to "Rational design" patented technology

Electrochemical cell including functionally graded and architectured components and methods

Electrochemical cells or batteries featuring functional gradations, and having desirable, periodic configurations, and methods for making the same. One or more methods, in alone or in combination, are utilized to fabricate components of such electrochemical cells or batteries, which are designed to achieve certain thermal, mechanical, kinetic and spatial characteristics, and their effects, singly and in all possible combinations, on battery performance. The thermal characteristics relate to temperature distribution during charge and discharge processes. The kinetic characteristics relate to rate performance of the cells or batteries such as the ionic diffusion process and electron conduction. The mechanical characteristics relate to lifetime and efficiency of the cells or batteries such as the strength and moduli of the component materials. Finally, the spatial characteristics relate to the energy and power densities, stress and temperature mitigation mechanisms, and diffusion and conduction enhancements. The electrochemical cells or batteries constructed according to the methods presented in this invention are useful for all applications that require high rate performance, high energy / power density, good durability, high safety and long lifetime.
Owner:SAKTI3

Computational method for design and manufacture of electrochemical systems

A method for manufacturing an electrochemical cell. The method includes generating spatial information including an anode geometry, a cathode geometry, a separator geometry, and one or more current collector geometries. The method also includes storing the spatial information including the anode geometry, the cathode geometry, the separator geometry, and the one or more current collector geometries into a database structure. In a specific embodiment, the method includes selecting one or more material properties from a plurality of materials and using the one or more material properties with the spatial information in a simulation program. The method includes outputting one or more performance parameters from the simulation program.
Owner:SAKTI3

Ground fault circuit interrupters with miswiring or reverse wiring protection and end of life alarm signal

This invention provides protection against an electricity leak and prevents error in reverse wiring. Also, when the ground fault circuit interrupter has come to the end of its life and its functions fail, it can set off an alarm prompt signal, reminding the user to replace the interrupter in a prompt manner; when a certain part or accessory of the ground fault circuit interrupter fails, especially when the primary electromagnetic coil cannot work in a normal manner, the power output of the interrupter may be cut off through the secondary electromagnetic coil; or the test button may be pressed to mechanically cut off the power output of the interrupter. This invention has powerful applications, with good safe guard and is safe to use, thus effectively ensuring the personal safety of the user as well as the safety of the appliances.
Owner:SHANGHAI MEIHAO ELECTRIC

Equipment for pressurized adsorption and liquification of carbon dioxide from boiler flue gas for oil recovery by well injection

An equipment for the pressurized adsorption and liquification of carbon dioxide from boiler flue gas for oil recovery by well injection comprising boiler for generating high pressure steam 1, high pressure water pump 2, tower scrubber 3, compressor 4, absorber 5, separation tank 6, flash pot 7, solvent pump 8, stripper 9, air pump 10, carbon dioxide compressor 11, purifier 12, liquefier 13, congealer 14, rectifying tower 15, condenser 16, storage tank 17, drying beds 18, membrane module 19, nitrogen pressurizer 20, carbon dioxide pump 21 and mixing tank 22. With rational design and handsome practicability, the comprehensive mate equipment, when producing steam by the boiler, can obtain carbon dioxide liquid and nitrogen, thus realizing “single injection”, “double injection” or “triple injection” of steam, gaseous carbon dioxide and nitrogen and thereby gaining favorable results of crude oil output increase as well as environment protection.
Owner:LIAOHE GASOLINEEUM EXPLORATION BUREAU

Plasma Oil-free Ignition System in Oxygen Enriched Environment

A plasma oil-free ignition system in oxygen enriched environment comprises a plasma generator and a burner. The plasma oil-free ignition system comprises a sleeve group coaxially arranged with the burner, and the sleeve group comprises multiple coaxially sleeved sleeves. Annular spaces are formed between adjacent sleeves and between the sleeves and the burner. Oxygen ducts are arranged on the sleeves, and oxygen ducts are arranged on the burner. Plasmas jetted by the plasma generators form a local high temperature zone filled with high temperature plasma and pulverized coal air flow. A certain amount of oxygen is fed to the burner through the oxygen duct therein to form local oxygen enriched zones in the annular spaces and the subsequent adjacent spaces through which air flows, thus realizing oxygen enriched combustion of volatile matters or coke or mixture thereof, and combustion the pulverized coal air flow more intensely to release more heat so as to ignite the primary air pulverized coal air flow quickly and burn the pulverized coal air flow stably. The invention has simple structure, is applicable to different coal types, especially applicable to the plasma oil-free ignition system in oxygen enriched environment of coal types with low volatile matters.
Owner:ZHENG LU +3

Cyclic bridgehead ether dgat1 inhibitors

The invention relates to compounds of formula (I):useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
Owner:NOVARTIS AG

Equipment for pressurized adsorption of gaseous carbon dioxide from boiler flue gas for oil recovery by well injection

InactiveUS20080236811A1Increase crude oil productionPromote resultsCombination devicesGas treatmentFlue gasAir pump
An equipment for the pressurized adsorption of gaseous carbon dioxide from boiler flue gas for oil recovery by well injection comprising a boiler for generating high pressure steam, a high pressure water pump, a tower scrubber, a compressor, an absorber, a separation tank, a flash pot, a solvent pump, a stripper, an air pump, a carbon dioxide compressor, a purifier, a carbon dioxide pressurizer, a drying beds, a membrane module, a nitrogen pressurizer and a mixing tank. With rational design and handsome practicability, the comprehensive mate equipment, when producing steam by the boiler, can obtain carbon dioxide liquid and nitrogen, thus realizing “single injection”, “double injection” or “triple injection” of steam, gaseous carbon dioxide and nitrogen and thereby gaining favorable results of crude oil output increase as well as environment protection.
Owner:LIAOHE GASOLINEEUM EXPLORATION BUREAU

Hand lever for a binding machine

A binding machine includes a tightening mechanism adapted to tension a belt and a limiting mechanism adapted to limit tensioning of the belt. The tightening mechanism includes, for example, a ratchet and a pawl coupled to a body of the tightening mechanism. A handle is adapted to rotate the ratchet in a first direction in response to a first force applied to the handle. The pawl is adapted to prevent the ratchet from returning in a second direction when the first force is released. A spring mechanism allows the handle to indicate when a second force opposing the first force achieves an established magnitude.
Owner:ASIAN IND PROD USA INC

Hepatic lobule-like bioreactor

The present invention provides a hepatic lobule-like bioreactor. The bioreactor includes a nanofiber scaffold enclosed within a housing. An intrahepatic fibrous vascular network, a bile capillary network, upper hepatic bile ducts, lower hepatic bile ducts, a common bile duct connecting the upper and the lower hepatic bile ducts, and collagen fibrous microchannels for hepatocytes surrounded by the bile capillary network are distributed throughout the nanofiber scaffold. Bile capillaries in the bile capillary network are provided with two or more inlet ports for biliary epithelial cells. The collagen fibrous microchannels for hepatocytes are provided with two or more inlet ports for hepatocytes. The intrahepatic vascular network is provided with a liquid inlet port and a liquid outlet port. These ports extend through the housing.
Owner:ZHEJIANG UNIV

Organic compounds

The invention relates to compounds of formula (I):where A is an optionally substituted heteroaryl, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
Owner:NOVARTIS AG

Small interfering RNAS as non-specific drugs

The present invention is directed to a method of modulating (e.g., inducing, inhibiting) activation of a double stranded RNA (dsRNA) signaling pathway, such as the dsRNA signaling pathway that accompanies RNA interference (RNAi) of a target RNA sequence, in a cell, comprising introducing into the cell small interfering RNA (siRNA) that degrades the target RNA sequence, and maintaining the cell under conditions in which RNAi of the target RNA sequence occurs and activation of the dsRNA signaling pathway is modulated in the cell.
Owner:THE CLEVELAND CLINIC FOUND

Disassembly / assembly tool

An improved disassembly / assembly tool in the technical field of machine is disclosed. The tool is characterized in that periphery of the rotating ring is covered with a hand wheel in which a luminous mechanism is fixed and a storage battery is provided in the handle. The said luminous mechanism is connected to the storage battery via an electric circuit structure. The tool has the following advantages: 1. the illumination can be realized and convenience of working is effectively increased, while not being affected by external environmental factors easily; 2. rational design, simple and compact structure, high strength, and easy for operation; 3. stable joggling portion, high operation stability, not causing locking, and long service life; 4. diverse functions. The tool not only can be used as a disassembly / assembly tool but also can be used as an electric torch under certain conditions.
Owner:SHANGYU HUANZHOU TOOLS

Organic compounds

The invention relates to compounds of formula (I):where A is an optionally substituted heteroaryl, useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
Owner:NOVARTIS AG

Connecting device for light fixtures

A connecting device for light fixtures has a lens fixing plate, a light fixture assembly, a button, a first spring, a connecting rod and a buckle. The buckle is fixedly connected to the light fixture assembly. A mounting base is disposed on the lens fixing plate. One end of the connecting rod is located in an inner cavity of the mounting base and the other end thereof is extended out from the mounting base. The end of the connecting rod extending out from the mounting base is provided with a boss, and the connecting rod located in the inner cavity of the mounting base is sleeved with the first spring. The button is connected to the end of the connecting rod located in the inner cavity of the mounting base.
Owner:WAC LIGHTING DONGGUAN +1

LED Lamp Beads with Multiple Light-Emitting Points

LED lamp beads with multiple light-emitting points comprising a certain number of luminous bodies and package resins; in which after at least two luminous bodies are connected in parallel, they are wrapped in a package resin and connected to an anode pin and a cathode pin inserted into the package resin. The present invention structure is simple and has a rational design. By using one-way conductive luminance on the LED luminous bodies, and using parallel and inverse parallel connections on multiple light-emitting points, control of the electric current direction is achieved, and thus the control of the operating modes of luminous bodies and the LED lamp beads with multiple light-emitting points is achieved.
Owner:DONGGUAN CHEN CAI ILLUMINATING TECHNOLOGY CO LTD

LED lamp beads with multiple light-emitting points

LED lamp beads with multiple light-emitting points comprising a certain number of luminous bodies and package resins; in which after at least two luminous bodies are connected in parallel, they are wrapped in a package resin and connected to an anode pin and a cathode pin inserted into the package resin. The present invention structure is simple and has a rational design. By using one-way conductive luminance on the LED luminous bodies, and using parallel and inverse parallel connections on multiple light-emitting points, control of the electric current direction is achieved, and thus the control of the operating modes of luminous bodies and the LED lamp beads with multiple light-emitting points is achieved.
Owner:DONGGUAN CHEN CAI ILLUMINATING TECHNOLOGY CO LTD

Mutant 4-hydroxyphenylacetate 3-hydroxylases and uses thereof

The present invention relates to genetically modified enzymes obtained by rational design of the active site binding pocket of the prototypic enzyme 4-hydroxyphenylacetate 3-hydroxylase (4HPA3H) for hydroxylating a 4-hydroxyphenyl compound to yield a 3,4-dihydroxyphenyl compound and to biotechnological methods including in vivo and in vitro methods using said enzymes or catalytically active fragments thereof. Further provided is a method either using a suitable oxidase or hydroxylase further enabling the subsequent site specific methylation of the 3,4-dihydroxyphenyl compound in a coupled enzymatic reaction by providing a suitable O-methyltransferase. Finally, compositions obtainable by the aforementioned methods are disclosed.
Owner:SYMRISE GMBH & CO KG +1

Cyclic ether dgat1 inhibitorscyclic ether dgat1 inhibitors

The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
Owner:NOVARTIS AG

Method for determining co-receptor selectivity of human immunodeficiency virus-1

Newly discovered structural characteristic of the gp120 V3 loop have resulted in a “rule” or algorithm, that is used in a method for determining whether a subject is infected with HIV-1 virus that expresses selectivity for CXCR4 or CCR5 chemokine receptors. A positively charged surface patch defined by V3 loop residues 11 and 24 or 25 at the base of the β-strands in the V3 loop and the homologous β2-β3 chemokine hairpin is responsible for CXCR4 receptor selection. Thus a method for detecting the presence of HIV-1 virus that is selective for X4-co-receptors in a subject infected with HIV-1 or suspected of being infected, from the amino acid sequence of at least a part of the HIV-1 gp120 V3 region peptide that includes residues 11, 24 and 25, or from the nucleotide sequence of a nucleic acid encoding said V3 region peptide, is disclosed.
Owner:NEW YORK UNIVERSITY

Cyclic ether DGAT1 inhibitorscyclic ether DGAT1 inhibitors

The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
Owner:NOVARTIS AG
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