The present invention relates to pet sock and a manufacturing method thereof, relating to the technical field of pet supplies. The present invention has solved the technical problems in the prior arts and provides a much more reasonable design. The pet sock provided by the present invention each comprises a sock body, a sock bottom for accommodating a foot of a pet which is communicated with the sock body, and a sock opening for a foot of a pet to get in or out being provided on the sock body, the pet sock being characterized in that an elastic waterproof layer made of elastic waterproof material is compounded on an outer side of the sole of the sock bottom. Compared with the prior arts, the pet sock and the manufacturing method thereof have the following advantages: the design of the pet sock is much more rational and the structure thereof is simpler; as an anti-slide-off structure is provided, the sock can be secured onto the leg of the pet and are unlikely to slide off; meanwhile, due to the arrangement of a shield sleeve, the anti-slide-off structure can be shielded, so that the pet sock look more beautiful and become warmer; in addition, the arrangement of the elastic waterproof layer can provide much more comfort and protect the feet of pets from injuries.