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177results about How to "Minimize discomfort" patented technology

Autonomous, ambulatory analyte monitor or drug delivery device

ActiveUS7004928B2Improve capillary forceMinimize coagulationAutomatic syringesMicroneedlesBiomedical engineeringElectronic equipment
The invention relates to analyte monitoring / drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.
Owner:INTUITY MEDICAL INC

Autonomous, ambulatory analyte monitor or drug delivery device

The invention relates to analyte monitoring / drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user. The invention can optionally provide for calibration without intervention of the user. The invention can also provide for semi-continuous monitoring for day and night time. The invention can provide for up to four, or more, weeks of operation. The invention can provide for a device that is relative small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents including high potency drugs to minimize patient intervention and minimize discomfort.
Owner:INTUITY MEDICAL INC

Nasal cannula retainer

A nasal cannula apparatus is provided for use by patients desiring a comfortable arrangement. The nasal cannula apparatus is particularly suited for long-term oxygen users, for extended wear in both standing, resting and supine positions. The nasal cannula apparatus has headgear and retainers for holding the gas supply tubes, which are adjustable to allow fast and easy adjustment to size. The headgear and retainers allow the cannula tubes to be held in a position which prevents skin discomfort and irritation, and which promotes healing of such irritation, injuries and sores.
Owner:MCKOWN JOSEPH R

A respiratory aid system and method

A system and method is disclosed for the provision of assisted breathing by the delivery of a controlled pressurized airflow to the pulmonary airway of a user with breathing disorders. The system comprises a source of compressed respiratory gas, a user nasal interface unit including at least one Venturi device and a thin flexible tubing connecting between the source of high pressure gas and the Venturi device. The system and method provide a regulated and controlled flow of air to the user in accordance with the user needs. The invention further discloses a novel small light-weight nasal user interface for replacing prior art breathing masks.
Owner:MATARASSO HASDI

Measuring pressure

A method and apparatus are disclosed for determining a negative pressure generated by a suction pump of a topical negative pressure (TNP) system. The method includes the steps of disconnecting a drive voltage from a pump of the TNP system, determining an EMF generated by a free-wheeling element of the pump, selecting a new drive voltage for the pump and reconnecting the new drive voltage to the pump.
Owner:SMITH & NEPHEW INC

Instrument for surgically cutting tissue and method of use

An instrument for precisely cutting tissue to controlled dimensions (length, width, depth, and shape) is provided for the removal of tissue specimens from remote sites in the body of a patient, such as from the gastrointestinal tract, urinary tract, or vascular structures, or any tissue surface or soft tissue of the body. The instrument has a housing and a substantially flexible shaft extending from the housing to a distal end. The distal end of the instrument has an open cavity into which tissue is receivable. Suction can be communicated along the shaft to the distal end for distribution across the cavity utilizing a manifold having a grated tissue engaging surface with opening(s) for applying the suction, thereby pulling tissue adjacent to the distal end into the cavity against the tissue engaging surface of the manifold. One or more hollow needles are extendable from the housing through the shaft into the cavity to enable infusion of fluid, such as saline or a hemostatic agent, into the tissue. A blade in the distal end is extendable through the cavity over the manifold and across the opening to cut the tissue held by suction and stabilized by the needles in the cavity. The shape and depth of the tissue removed by the cuts is in accordance with the contour of the tissue engaging surface and the size and shape of the cavity at the distal end. The tissue so removed by the instrument may be for therapeutic intervention and / or represent a tissue specimen for biopsy suitable of diagnostic evaluation. The tissue edges in the patient's body left after cutting with this instrument readily avail themselves to apposition for enhanced healing.
Owner:LSI SOLUTIONS

Pain relief composition

InactiveUS7282224B1Long-termEffective and comfortable to applyBiocideOrganic active ingredientsGlucosamine SulfateMedicine
Disclosed is a pain relief composition comprising an effective amount of a nerve inhibiting component, including capsaicin, a capsaicinoid or a capsaicin analogue, which numbs or inhibits the nerve endings that signal pain, in combination with at least one of the following: an effective amount of an inflammation control component which is designed to reduce immediate pain and discourage future pain in the joints and muscles; an effective amount of a cooling component; an effective amount of a heat minimizing or blocking component; an effective amount of a circulation increasing component which effectuates better penetration of the actives to the skin and nerves; and an effective amount of a soothing and anti-inflammatory complex for the joints and / or muscles comprising Glucosamine sulfate or HCl, Zingiber officiniale (Ginger Root) extract, Methyl sulfonylmethane (MSM), Polygonum cuspidatum (Mexican Bamboo) extract, Aloe barbadensis leaf, and Salix alba (white willow) bark extract. Additionally, the composition includes an encapsulation or entrapment system for a timed release delivery.
Owner:GUTHY-RENKER

Virtual monitor display technique for augmented reality environments

Methods, apparatus, and computer-readable media are described herein related to a virtual monitor display technique for augmented reality environments targeted at allowing a user of a display-enabled computing device to substitute their conventional hardware-realized display screen with a virtualized display screen of equal or better usability characteristics than the hardware-realized device. A virtual screen is rendered via a micro display in an augmented reality environment to a human user wearing a see through head mountable device. The system architecture makes use of liquid lens technology in order to adjust the relative position of the display as well as the focal distance by optical means only thereby ensuring that the virtual screen is rendered at the maximum resolution of the micro display at all times. The system architecture also comprises an occlusion matrix thereby ensuring that the virtual screen is free of ghosting. The system is configured in such a way that a display auto-hide function is triggered whenever certain threshold parameters are exceeded. The virtual monitor display technique described herein has been designed with the aim of reducing the effects simulator sickness during prolonged use of the virtual display.
Owner:VON & ZU LIECHTENSTEIN MAXIMILIAN RALPH PETER

Bis(thiohydrazide amides) formulation

Disclosed herein are compositions and methods useful for the in vivo delivery bis(thiohydrazide amides), encased in a polymeric biocompatible shell.
Owner:SYNTA PHARMA
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