The invention provides a space flexible arm pressing and releasing mechanism for fuse unlocking, which belongs to the technical field of space flexible arm pressing and releasing mechanisms. The invention includes a fixed base, a fuse unlocking device, a pressing cover, a position detection micro switch, a phenyl silicone rubber sheet, a torsion spring, a pin shaft and a limit micro switch; before launching, adjust the position of the fuse unlocking device The locking device exerts an appropriate pre-tightening force on the pressing cover plate through the pull rope, so that the space flexible arm is pressed on the fixed base. After entering orbit, the ground sends a command to energize the cutter of the fuse unlocking device, and the resistance wire of the cutter heats up rapidly to fuse the pull rope. The present invention is reliable in compression, adopts the fusible wire unlocking device as the compression and unlocking tool, has a simple structure, can apply more accurate pre-tightening force, and is convenient for assembly and adjustment; there is no shock and vibration when unlocking, and can protect the space flexible arm from being damaged when launching. The damage caused by vibration and shock load is suitable for occasions where the locking force of the space flexible arm is not required.