1345results about "Pathological references" patented technology

BioMEMS / NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.

A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and / or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and / or halt the delivery of medication to the patient until the alert is resolved.

The method of the present invention derives the illness probability of any selected person from a database of people stored in a computer and / or on a computer network using collected relational data from every person in the database, including whether a person has a contact relationship with another person in said database and utilizes a database of illnesses infection probability functions given different illnesses and states of nature including data relating to social relationship; type of disease; probability function of infection given a time unit; length of contact of the particular contact relationship link; and calculates at least one relational path between said person and each person in the data base with whom there is a contact relationship, direct or via other persons in the said database for deriving the illness probability of the selected person. In addition. the method of the present invention permits selecting the optimum treatment for a patient with an infectious disease based upon recommending a drug or drugs deemed optimum for treating the patient and permits generating alerts for the detection of emergency events such as the outbreak of an infectious disease or a biological, chemical or nuclear attack and for diseases management. Moreover, in accordance with the method of the present invention a given patient may compare his or her medical record with summary information of patients with similar defined criteria.

There is provided a system for the delivery of medicament comprising a medicament container; a dispensing mechanism for dispensing medicament from the medicament container; an electronic data management system; and a communicator for wireless communication with a network computer system to enable communication of data between the network computer system and the electronic data management system. The electronic data management system comprises a memory for storage of data; a microprocessor for performing operations on the data; and a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data.

A system and method for providing goal-oriented patient management based upon comparative population data analysis is presented. At least one therapy goal is defined to manage a disease state. A patient population is selected sharing at least one characteristic with an individual patient presenting with indications of the disease state. One or more treatment regimens associated with the patient population are identified as implementing actions under the at least one therapy goal. The implementing actions are followed through one or more quantifiable physiological indications monitored via data sources associated with the patient.

A system utilizing a personal security device to provide access to a computer terminal where the personal security device includes circuitry and transceiver components for transmitting identification information and exchanging other digital information with a computer terminal and other compatible devices and the personal security device establishes a communication link with a computer terminal to allow a user to logon to the terminal so that when a user leaves the computer terminal, the communication link is terminated, causing the computer terminal to lock the keyboard, blank the monitor, and / or logoff the user if the communication link is not restored within a sufficient time period and also allowing the personal security device to facilitate subsequent computer access within a time range by providing time related access codes to the terminal that can be used to reestablish computer terminal access.

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

A technique is provided for offering feedback, including feedback for patient care and for training purposes for medical professionals and human operators. The technique includes accessing data, such as image data, for evaluation by a human operator. The data is then analyzed via a computer-assisted data operating algorithm, and the analysis may further include analysis of supplemental data accessed from an integrated knowledge base. Based upon the analysis feedback is provided to the operator, such as for completing or complementing the evaluation, correcting analysis by the human operator, or otherwise informing the human operator of similarities or differences between the analyses.

The systems described herein include tools for computer-assisted evaluation of objective characteristics of pathologies. A diagnostic system arranged according to the teachings herein provides computer support for those tasks well suited to objective analysis, along with human decision making where substantial discretion is involved. Collaborative diagnosis may be provided through shared access to data and shared control over a diagnostic tool, such as a telemicroscope, and messaging service for clinicians who may be at remote locations. These aspects of the system, when working in cooperation with one another, may achieve improved diagnostic accuracy or early detection for pathologies such as lymphoma.

A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and / or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and / or halt the delivery of medication to the patient until the alert is resolved.

A system and related method for identifying a trigger event to a patient health-related exacerbation. The system includes at least one sensor configured to collect data related to the patient health-related exacerbation, an analyzer configured to validate the collected data, a patient interface device configured to receive patient inputs to at least one question, and an identifier device configured to receive the patient inputs and collected data and identify the trigger event. The system may also include an expert system configured to receive the patient inputs and the validated collected data and identify a primary patient disease, and a reporting device configured to generate reports related to the identified primary patient disease, patient inputs, and sensed patient conditions.

A software-based, integrated member decision support system provides a method for corporations, insurance carriers, health maintenance organizations, physicians, physician groups, or other clients to efficiently provide medical, pharmaceutical, and health benefit advice and information for an enrolled population. The system contains one or more databases which include member profiles, clinical information and guidelines, pharmaceutical information and guidelines, health benefit information, and optional additional information. A caller establishes communication with the system, which directs the caller to an operator who provides the caller with medical, pharmaceutical, and / or health benefit advice based on an inquiry from the caller and the information stored on the system. The system may automatically alert the caller or the operator of important medical or pharmaceutical information. At the conclusion of the call, the system or the system with the operator's input, may update the caller's member profile, request written materials, generate referrals, order prescriptions, or generate reports.

Embodiments of the invention relate to systems and methods for cloning a production database for quality assurance (QA) by the merchant users. A QA user may request tokens, card types and other data associated with a payment device for quality assurance purposes. The payment network redirects the QA request to a go-between database that is present between the QA user and the production environment of the payment network rather than pull the information directly from the production environment. As a result, the merchant is able to use tokens for testing, without violating consumer privacy and security rules and regulations (e.g., PCI rules). The QA user does not have to create a customized testing solution.

Embodiments of the invention provide a method and apparatus for a wireless health monitoring system for interactively monitoring a disease or health condition of a patient by connecting an internet-enabled wireless web device (“WWD”) to a digital camera or other health monitoring device. The WWD may accommodate a memory device for enhanced storage capabilities that may be particularly pertinent to data-intensive tasks such as the handling and storage of images or other visual data. The health related data is transmitted from the WWD to a server using standard internet protocols and may be integrated with various operating systems for handheld or wireless devices, especially those with enhanced capabilities for handing images and visual data.

A system for analyzing a source medical image of a body organ. The system comprises an input unit for obtaining the source medical image having three dimensions or more, a feature extraction unit that is designed for obtaining a number of features of the body organ from the source medical image, and a classification unit that is designed for estimating a priority level according to the features.

A clinical reference and education system and method of use, wherein medical condition diagnosis information is gathered, stored, and distributed. More specifically, information regarding clinical / pathological differential analyses, key facts, clinical presentations, pathology features, imaging findings, anatomy information, medical references with abstracts, expert imaging center information, continuing medical education information, and related data is made available in electronic and printed forms via a general infrastructure of the present system.

A method for creating and searching medical ontologies includes providing a semi-structured information source comprising a plurality of articles linked to each other, each article having one or more sections and each article is associated with a concept, creating a directed unlabeled graph representative of the information source, providing a plurality of labels, labeling a subset of edges, and assigning each unlabeled edge an equal probability of being assigned one of the labels. For each node, the probability of each outgoing edge is updated by smoothing each probability by an overall probability distribution of labels over all outgoing edges of each node, and the probability of each incoming edge is updated the same way. A label with a maximum probability is assigned to an edge if said maximum probability is greater than a predetermined threshold to create a labeled graph.

A wireless virtual local area network (VLAN) and a device selectively connecting to the wireless VLAN over a second wireless network that may be independent of the wireless VLAN. The device is capable of connecting to at least the wireless VLAN and to the second wireless network. Wireless VLAN access points are each connected to an Ethernet aggregation switch, which is VLAN aware and matches client traffic from connected access points with access VLANs. A wireless VLAN switch maintains an association table between access VLANs and core VLANs. The second wireless network may be remotely connected over the Internet or a private network to a tunnel endpoint. The tunnel endpoint is connected to the VLAN switch, which uses the association table to manage free-form client traffic between connected devices and other mobile stations at access VLANs and appropriate core VLANs.

A medical database and associated methods are especially suited for compiling information in a medical malpractice situation. A general medical database is provided and specific medical information corresponding to a given situation is entered. Entry of the information automatically cross-references some terms of the entered data to definitions in the general medical database. Terms are readily looked up when reviewing specific medical information and definitions are easily inserted where desired. A drug reference display provides two-way lookup from drugs to their side effects (or contraindications or interactions) and back. Significant information from an entered medical chronology is easily copied to a significant information section when a reviewer finds the information important.

A system for generating a report having varying integrated levels of medical information related to a health condition is provided. The system comprises a host server having a host database and a client component that connects to the host server. The client component includes a report software application that is configured to generate a report and provide a GUI on the display. A processor populates the GUI based upon received and processed medical information from the host server component and arranges the medical information in predetermined, inter-related levels. A cursor is provided to allow the user to point to an area of interest in the display and a further level of information pertaining to one or more layers of medical information is viewable by a user when the cursor is pointed over an image on the display.

A method of assessing risk for an individual to experience a specific outcome within a disease entity within a specified time frame is provided. Peer-reviewed scientific publications are analyzed to identify pertinent risk factors (212) for developing disease processes and their possible complications. Information that characterizes an individual (218) in relation to the identified risk factors is then received, preferably responsive to question (224) regarding any demographic values of an individual under test and questions regarding medical chracterisitics of the individual under test. An estimate of risk of the individual acquiring the outcome within a specified time frame is performed based on the identified plurality of risk factors (212). Assessment of medical risk and condition may include analyzing peer-reviewed scientific publications to identify populations affected by a medical outcome and for each population respective risk factors that affect risk of acquiring the medical outcome within a specified time-frame, associating an individual with one of the identified population, identifying information that characterizes the individual (218) in relation to the respective risk factors other associated population, and estimating risk of the individual having the medical outcome within the specified the time frame responsive to the identified information. Promotion of business on a site of a computer network is provided by supplying an on-line questionnaire (224) regarding characteristics of individual (218) under test, receiving information regarding characteristics of the individual under test, and responsive to the received information, providing an assessment of the individual under test having a medical outcome within a specified time frame.

The Electronic Compliance Promoter is a computer system for increasing a patient's compliance with medical post-care treatment instructions. The system permits the patient to review the treatment instructions that have been entered into a treatment instructions database by medical personnel at the time of the examination. The system includes a patient-client computer interface, a medical person-client interface, a treatment instructions database, and a compliance-server program. The database contains the post-visit care instructions and other types of information that the patient should have to understand and follow those instructions. The database also has treatment guideline information to assist the doctor in formulating the post-care treatment instructions. The patients client-computer interface provides a knowledge-based means for the patient to review interactively the Doctor's after care instructions, and measures compliance by tracking a patients' use of the specific designated diagnosis related resources. The medical personnel client-computer interface provides a knowledge-based means to designate the post-care medical visit instructions the patient is to follow. The compliance-server program tracks patients compliance and can send messages to patients reminding them to review the post-care treatment instructions. The Electronic Compliance Promoter system provides a means to significantly increase a patient's compliance with medical care instructions.

Systems, methods and computer program products for guiding selection of a therapeutic treatment regimen or a preventive therapeutic treatment regimen are disclosed. The method comprises (A) providing to a computing device comprising a first knowledge base comprising information about a plurality of different methylation statuses at selected sites of the DNA in cells with a known disease or medical condition and / or healthy cells, a second knowledge base comprising a plurality of expert rules for evaluating and selecting a type of disease or medical condition based on the methylation status at selected sites of the DNA of a patient, (B) generating in said computing device a ranked listing of diseases or medical conditions based on the information about the methylation status at selected sites of the DNA of the patient, the first knowledge base and the second knowledge base.

A method of evaluating and / or optimizing clinical outcomes and providing rational pharmacotherapy in an individual or animal requiring chronic drug therapy is provided.

A computer-implemented method and system are provided for assisting a plurality of patients manage chronic health conditions. The method, for each patient, comprises: (a) receiving information from the patient or a member of a patient care network on an expected patient activity at a given future time period; (b) determining expected transient local ambient conditions in the patient's surroundings during the expected patient activity at the given future time period; (c) predicting health exacerbations for the patient using a stored computer model of the patient based on a desired patient control set-point range, the expected patient activity, and the expected transient local ambient conditions; and (d) proactively sending a message to the patient or a member of the patient care network before the given future time period, the message alerting the patient or a member of the patient care network of the predicted health exacerbations for the patient and identifying one or more corrective actions for the patient to avoid or mitigate the predicted health exacerbations.

A system and method for creating links between first records stored on a database and references to the first records within a second record, the system including a data reference list including keywords or phrases which may be used in the second record to reference the first records, the system also including address formats corresponding to each data reference which indicate the form of a first record address corresponding to the data reference, the system also including record rule sets for gleaning information from the second record for populating the address format, when a data reference is identified, the system identifying the corresponding address format, gleaning address information from the second record, forming the record address and linking the first record reference to the first record via the record address.

Systems and methods for visualization and interactive navigation of virtual images of internal organs are provided to assist in medical diagnosis and evaluation of internal organs. In one aspect, an image data processing system (105) includes an image rendering system (111) for rendering multi-dimensional views of an imaged object from an image dataset (106) of the imaged object, a graphical display system (112) for displaying an image of a rendered view according to specified visualization parameters, an interactive navigation system (107) which monitors a user's navigation through a virtual image space of a displayed image and which provides user navigation assistance in the form of tactile feedback by a navigation control unit (115) operated by the user, upon an occurrence of a predetermined navigation event.