43 results about "Therapy alcoholism" patented technology

The present invention provides for the use of combinations of drugs to treat addictive disorders. More specifically, the present invention provides compositions and methods for treating disorders using combinations of drugs such as topiramate, ondansetron, and naltrexone.

Alcoholism, and symptoms and negative effects thereof may be treated using ibudilast or a pharmaceutically acceptable salt thereof. Abstinence from alcohol consumption may be maintained using ibudilast or a pharmaceutically acceptable salt thereof. Withdrawal from alcohol may be facilitated and negative effects thereof reduced by using ibudilast or a pharmaceutically acceptable salt thereof.

The present invention relates to a medicine for curing alcoholism-metadoxine freeze-dried powder injection and its preparation process. The proper quantity of anti-oxidant and chelator can be added in its medicine preparation formula composition so as to raise the stability of said medicinal component. The pharmacodynamic tests show that it has remittence action for rat liver injury due to carbontetrachloride. Said injection is stable, and is favorable for storage and transportation.

The invention provides transdermal patches comprising an adhesive and a composition comprising naltrexone and either methyl oleate or isopropyl myristate, a kit comprising a plurality of such transdermal patches, a composition comprising naltrexone and methyl oleate, such a composition for use as a medicament, and compositions comprising naltrexone and methyl oleate or isopropyl myristate for use in the treatment of alcoholism or opiate addiction.

The present invention features compositions for intranasal administration comprising an opioid receptor antagonist. The invention also features methods of using such compositions in the treatment of various diseases and disorders, such as the treatment of alcoholism. In certain embodiments, the opioid receptor antagonist is naltrexone or a pharmaceutically acceptable salt thereof.

The present invention provides an implantable composition which contains disulfiram, an anti-inflammatory agent, and optionally a pharmaceutically acceptable carrier. Methods of making the implants, and methods of using the implants to treat alcoholism and opioid dependency are also disclosed.

The invention provides transdermal patches comprising an adhesive and a composition comprising naltrexone and either methyl oleate or isopropyl myristate, a kit comprising a plurality of such transdermal patches, a composition comprising naltrexone and methyl oleate, such a composition for use as a medicament, and compositions comprising naltrexone and methyl oleate or isopropyl myristate for use in the treatment of alcoholism or opiate addiction.

The invention discloses a Chinese herbal compound preparation used for treating alcoholism and gout, mainly comprising the following components in parts by weight: 10-40 parts of kudzuvine root, 15-40 parts of hovenia acerba, 3-10 parts of pseudo-ginseng, 3-15 parts of phyllanthus emblica, 3-10 parts of fructus amomi, 35-10 parts of myristica fragrans, 3-15 parts of dchisandra chinensis, 4-15 parts of American olive, 10-20 parts of honeysuckle, 10-30 parts of rhizoma smilacis glabrae, 10-30 parts of coix seed, 10-30 parts of poria cocos, 10-20 parts of zaocys dhumnade, 10-20 parts of lucid ganoderma, 10-20 parts of American ginseng and 10-20 parts of turmeric. No hepatorenal dysfunction is caused when the compound preparation disclosed by the invention is used for treating hyperuricosuria, which shows that the preparation has no obvious toxic or side effect and mild medicine property, thus the preparation is beneficial to long-term administration. The inventor also knows that medicine taking compliance of patients and tolerance are good from some follow-up visited patients, annual attack frequency is reduced, and the preparation disclosed by the invention has obvious treatment effect on combined diabetes mellitus, hyperlipidemia and vascular hypertension, thus the preparation disclosed by the invention can be regarded as a safe Chinese herbal compound preparation which can be taken by a patient who is repeatedly attacked by acute gouty arthritis for a long time and can control symptoms and reduce attack frequency.

The invention discloses an alcohol-dissolving liver-protecting healthy food, which comprises the following raw materials (by weight portion), hedgehog fungus 35-45 parts, kudzuvine root 25-35 parts, oyster 16-24 parts, licorice root 8-12 parts, white peony root 8-12 parts, nutgrass flatsedge rhizome 8-12 parts. The food can be prepared into capsules, tablets, pills, electuary or other dosage forms.

This application relates to a method for treating various aspects of alcoholism, including alcohol craving and relapse into alcoholism, by the administration of an effective amount of gaseous anaesthesia to a deep surgical anaesthesia. The method can be applied for the alleviation of addiction and craving associated with amphetamine use, and for the alleviation of psychosis in schizophrenia and the alleviation of psychosis in Alzheimer's disease. In addition, the state of addiction or the state of psychosis, or the state of alcohol withdrawal can be monitored in animal tissue in vitro or in humans in vivo by measuring the density of the high-affinity states of the dopamine D2 receptors in the striatum or other brains regions containing these receptors which are elevated in these conditions.

The invention discloses an alcohol-dissolving liver-protecting healthy food, which comprises the following raw materials (by weight portion), hedgehog fungus 35-45 parts, kudzuvine root 25-35 parts, oyster 16-24 parts, licorice root 8-12 parts, white peony root 8-12 parts, nutgrass flatsedge rhizome 8-12 parts. The food can be prepared into capsules, tablets, pills, electuary or other dosage forms.

The present invention relates to novel ACSS2 inhibitors having activity as anti-cancer therapy, treatment of alcoholism, and viral infection (e.g., CMV), composition and methods of preparation thereof, and uses thereof for treating viral infection, alcoholism, alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity / weight gain, anxiety, depression, post-traumatic stress disorder, inflammatory / autoimmune conditions and cancer, including metastatic cancer, advanced cancer, and drug resistant cancer of various types.

The invention provides a pharmaceutical composition for preventing or treating alcoholic poisoning and alcoholic liver damage and a preparation method thereof. The traditional Chinese medicine is prepared from raw materials of haw, Chinese yam, soya lecithin, and fructo-oligosaccharide. The pharmaceutical composition has the characteristics of definite therapeutic effect, little side effect, simple preparation method, and low cost, and provides a new choice for clinical application.

Provided are compounds having the general structure according to Formula (I):Further provided are pharmaceutical compositions comprising these compounds. The invention still further provides methods of treating alcoholism, methods of reducing alcohol intake, methods of treating anhedonia, and methods of treating anxiety using theses compounds or the compositions containing them.

Use is disclosed of (a) an AlDH-inhibitory amount of a Trp metabolite, or an analogue or derivative thereof or (b) a bioprecursor thereof, or (c) a potentiator of (a) and / or (b), in the preparation of a medicament for treating alcoholism and / or alcohol dependence.

The invention provides an anti-alcohol composition. The anti-alcohol composition comprises, by weight, 5-15 parts of Radix Puerariae, 5-15 parts of Flos Puerariae. 5-15 parts of Radix Sophorae Flavescentis, 3-10 parts of Myristica Fragrans, 8-20 parts of Fructus Gardeniae, 2-5 parts of tangerine peel and 2-5 parts of ginger. The method includes the following steps: crushing components in the anti-alcohol composition prior to mixing; (2) adding water to decoct the anti-alcohol composition for 1-2h; 3) filtering and collecting decoction, adding water into filtered dregs, and then decocting for 0.5-1h; (4) repeating the step (3) for 2-4 times prior to collecting decoction; (5) concentrating decoction to obtain oral liquid. The invention further provides application of the anti-alcohol composition in preparation of drugs for treating alcoholism.

Compositions and methods for treating, preventing, or reducing alcoholism, in particular methods for increasing patient compliance with therapies that require the intake of an ALDH inhibitor comprising the step of administering a monoamine oxidase B inhibitor.