The invention discloses an anti-saturation compensation method for an underwater high-speed vehicle actuator, and belongs to the technical field of ship engineering, control science and control engineering. An anti-saturation compensator system for the underwater high-speed vehicle actuator comprises an underwater high-speed vehicle longitudinal movement module, a longitudinal movement feedback linearization controller module which does not consider saturation, a performance index calculation module, an anti-saturation compensation module, a saturation detection module and a compensation effect simulation storage module. A design method for the anti-saturation compensator system comprises the following steps that: firstly, according to the Newton's laws of motion and the theorem of moment of momentum, establishing a kinetic model for underwater high-speed movement body longitudinal movement; then, according to the design steps of the feedback linearization controller, designing the controller; and finally, designing the anti-saturation compensator. By use of the compensator designed by the invention, the influence of saturation nonlinearity on system performance can be weakened, and the underwater navigation stability of the underwater high-speed vehicle is improved.