The invention belongs to the technical field of traditional Chinese medicines, and in particular discloses a Chinese medicine composition for treating hyperplasia of prostate and a preparation method of the Chinese medicine composition. The Chinese medicine composition is prepared from the following Chinese medicinal herbs in parts by weight: 5-10 parts of fried rhizoma atractylodis, 5-10 parts of amur cork tree bark, 5-15 parts of cortex mori radicis, 10-15 parts of plantain seed, 3-10 parts of parched pangolin, 3-10 parts of common burreed rhizome, 5-10 parts of fired semen vaccariae, 5-15 parts of lumbricus, 3-9 parts of safflower, 5-15 parts of Chinese angelica, 6-15 parts of medicinal cyathula root, 1.5-3 parts of amber, 10-60 parts of astragalus, 5-10 parts of ginseng, 3-15 parts of radix aconiti lateralis preparata and 5-10 parts of pulp of dogwood fruit. The Chinese medicine composition has the effects of clearing heat, promoting dieresis, nourishing qi, warming kidney, resolving hard lump, and dispersing blood stasis, and has quick treatment effect on the hyperplasia of prostate with definite treatment effect.