Pharmaceutical composition for treating benign prostatic hyperplasia and preparation method thereof

A prostatic hyperplasia and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of easy repeated side effects, slow treatment effect, single function, etc., and achieve pain relief, short course of treatment, The effect that is not easy to relapse

Inactive Publication Date: 2021-05-25
广东德鑫制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these compositions are all derived from ancient prescriptions and have not been improved in combination with modern medicine. There are generally problems such as slow therapeutic effect, single function, long course of treatment, easy repetition or large side effects.

Method used

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  • Pharmaceutical composition for treating benign prostatic hyperplasia and preparation method thereof
  • Pharmaceutical composition for treating benign prostatic hyperplasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 A kind of pharmaceutical composition for the treatment of benign prostatic hyperplasia

[0034] The pharmaceutical composition for treating benign prostatic hyperplasia consists of the following components and parts by weight: 39 parts of plant extracts, 6 parts of decanoyl acetaldehyde, 7 parts of tanshinone, and 2 parts of paeonol;

[0035] The plant extract is composed of Qumai extract, Rosa roxburghii extract and pinellia extract in a weight ratio of 20:13:6.

[0036] The preparation method of the Qumai extract is as follows:

[0037]S1. After crushing Qumai, pass through a 40-mesh sieve, then add petroleum ether with 6 times its volume and weight, reflux for 3 hours in a water bath at 50-70°C, reflux and extract twice, each time for 1 hour, filter the medicinal residues, and evaporate the petroleum ether to dryness. get the filtrate;

[0038] S2. Add 5 times the weight of ethanol with a mass concentration of 50% to the filtrate obtained in step S1 fo...

Embodiment 2

[0046] Embodiment 2 A kind of pharmaceutical composition for the treatment of benign prostatic hyperplasia

[0047] The pharmaceutical composition for treating benign prostatic hyperplasia consists of the following components and parts by weight: 47 parts of plant extracts, 8 parts of decanoyl acetaldehyde, 9 parts of tanshinone, and 5 parts of paeonol;

[0048] The plant extract is composed of Qumai extract, Rosa roxburghii extract and pinellia extract in a weight ratio of 23:15:9.

[0049] The preparation method of the Qumai extract is as follows:

[0050] S1. After crushing Qumai, pass through a 50-mesh sieve, then add petroleum ether with 12 times the weight of its volume, reflux for 3 hours in a water bath at 50-70° C., reflux and extract twice, each time for 1 hour, filter the medicinal residues, and evaporate the petroleum ether to dryness. get the filtrate;

[0051] S2. Add 7 times the weight of ethanol with a mass concentration of 60% to the filtrate obtained in ste...

Embodiment 3

[0059] Embodiment 3 a kind of pharmaceutical composition for the treatment of benign prostatic hyperplasia

[0060] The pharmaceutical composition for treating benign prostatic hyperplasia consists of the following components and parts by weight: 56 parts of plant extracts, 10 parts of decanoyl acetaldehyde, 12 parts of tanshinone, and 8 parts of paeonol;

[0061] The plant extract is composed of Qumai extract, Rosa roxburghii extract and pinellia extract in a weight ratio of 25:17:14.

[0062] The preparation method of the Qumai extract is as follows:

[0063] S1. Crush the quinces and pass through a 60-mesh sieve, then add petroleum ether 15 times its volume and weight, reflux for 3 hours in a water bath at 70°C, reflux for extraction twice, each time for 1 hour, filter the medicinal residues, and evaporate the petroleum ether to obtain the filtrate ;

[0064] S2. Add 8% ethanol with a mass concentration of 70% to the filtrate obtained in step S1 for ultrasonic extraction ...

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Abstract

The invention belongs to the technical field of medicine preparation, and particularly relates to a medicine composition for treating benign prostatic hyperplasia and a preparation method thereof. The pharmaceutical composition for treating benign prostatic hyperplasia is prepared from the following components in parts by weight: 39 to 56 parts of plant extract, 6 to 10 parts of decanoyl acetaldehyde, 7 to 12 parts of tanshinone and 2 to 8 parts of paeonol. The pharmaceutical composition for treating the prostatic hyperplasia can quickly relieve the symptoms of the prostatic hyperplasia, takes effect quickly, has the total effective rate of 91%, is short in treatment course and not prone to relapse, quickly relieves the pain of a patient, and treats the prostatic hyperplasia from multiple aspects and multiple targets.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and in particular relates to a medicine composition for treating benign prostatic hyperplasia and a preparation method thereof. Background technique [0002] Benign prostatic hyperplasia (BPH) is a condition in which the enlarged prostate compresses the prostatic urethra, or causes obstruction of the vesicourethral opening, resulting in frequent urination, difficulty urinating, or even inability to excrete urine, and can lead to urinary system infections, bladder stones, and hematuria and other complications, the main causes of benign prostatic hyperplasia are divided into dynamic factors and static factors, dynamic factors are mainly due to the increase of the prostate capsule and smooth muscle tension rich in α-receptors, which causes bladder irritation, Manifested as frequent urination, urgency, and in severe cases, urgency urinary incontinence may occur. The static factor is mai...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P13/08A61K31/11A61K31/12A61K31/58A61K36/36A61K36/738
CPCA61K31/11A61K31/12A61K31/58A61K36/36A61K36/738A61K36/8888A61K2236/331A61K2236/35A61K2236/51A61K2236/55A61P13/08A61K2300/00
Inventor 程水流陈永安向全生李燕刘长清
Owner 广东德鑫制药有限公司
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