The invention discloses a traditional Chinese medicine preparation for treating postpartum depression. The traditional Chinese medicine preparation is prepared from vinegared bupleurum chinensis, radix curcumae, parched radix paeoniae alba, mentha piperita, green tangerine orange peel, fried atractylodes macrocephala, poria cocos, rhizoma acori gramine, raw oyster shell, amber, bitter cardamon, snake gourd fruit, radix platycodi, wild jujube seed, shelled cedar seed, prepared polygala root, flower of silktree ablbizzia, red rose, multiflower knotweed vine, mother of pearl, angelica sinensis, toosendan fruit, Corydalis yanhusuo and raw glycyrrhiza uralensis according to a certain weight ratio. The traditional Chinese medicine preparation has the effects of soothing liver and relieving depression, clearing away heart-fire and relieving restlessness, clearing away damp-heat from head and eyes and warming, invigorating, inducing astringency and arresting discharge and can be used for effectively treating postpartum depression.