109 results about "New diagnosis" patented technology

The invention belongs to the field of the tumor molecule biology, in particular to a diagnosis reagent, a reagent knit and prevention and cure drugs of endometrial carcinoma, which provides a new diagnosis reagent and medicine for the early diagnosis and the prevention of endometrial carcinoma, and also provides a new method for filtering the medicine used for preventing endometrial carcinoma. The diagnosis reagent for endometrial carcinoma of the invention contains a reagent which can test the expressing level of a human cyclophilin A protein or the content of the mRNA of genes of the human cyclophilin A protein. The medicine which can prevent endometrial carcinoma of the invention includes: the expressing carrier of a shPNA molecule which can express the human cyclophilin A, etc. can change the expressing level of the human cyclophilin A protein or the mRNA content of the genes of the human cyclophilin A protein. The diagnosis reagent of the invention can be used for the early diagnosis of endometrial carcinoma, which has a wide application prospect.

The present invention is drawn to a new diagnosis method for detecting the extent of alcoholic or non-alcoholic steato-hepatitis in a patient, in particular in a patient suffering from a disease involving alcoholic or non-alcoholic steato-hepatitis or who already had a positive diagnosis test of liver fibrosis and / or presence of liver necroinflammatory lesions, by using the serum concentration of easily detectable biological markers. The invention is also drawn to diagnosis kits for the implementation of the method.

The invention discloses application of serine, which is used as a biological marker and has +79.96685 mass shift at a 208 site of AKAP3 (A-kinase Anchor Protein 3), to preparation of a diagnostic reagent or a treatment medicine of severe oligoasthenospermia. According to the application disclosed by the invention, the severe oligoasthenospermi can be diagnosed through testing frequency of the +79.96685 mass shift occurring at the 208 site of the AKAP3, and new diagnosis and new treatment target spots are provided for the severe oligoasthenospermia.

The invention discloses application of asparagine with AKAP4 protein 186th-site generating mass shift -113.05347 as a biological marker in preparing a reagent for diagnosing severe oligoasthenospermia. The fact that the detection frequency of the AKAP4 protein 186th-site generating mass shift -113.05347 can be used for diagnosing the severe oligoasthenospermia is found, so that a new diagnosis and treatment target is provided for the severe oligoasthenospermia.

The invention relates to vehicle diagnosis system and method based on an internet C / S mode. The method comprises the steps of: 1, establishing a connection between a terminal user and a server; 2, carrying out authentication on the terminal user and the server; 3, determining a vehicle type by the terminal user, sending the vehicle type information to the server to obtain a corresponding vehicle diagnosis program; 4, operating the diagnosis program, carrying out function diagnosis on the vehicle; 5, sending information to the server to obtain core library data required by the corresponding function; 6, computing the obtained core library data and displaying a result; and 7, judging whether ending the operation or not, if not, executing the next function diagnosis. The system is a C / S forming mode based on a certain central center on internet as a core, and has simple construction and convenient use. The method is convenient for uniform maintenance for the diagnosis core data, so that the fault of the vehicle can be accurately judged by using newest diagnosis data at any time as long as the server is linked.

The invention discloses application of lysine with AKAP4 protein 733rd-site generating mass shift +211.09682 as a biological marker in preparing a reagent for diagnosing severe oligoasthenospermia. The fact that the application has the advantage that the detection frequency of the AKAP4 protein 733rd-site generating mass shift +211.09682 can be used for diagnosing the severe oligoasthenospermia is found, so that a new diagnosis and treatment target is provided for the severe oligoasthenospermia.

The invention discloses application of asparagine with AKAP4 protein 186th-site generating mass shift -114.04278 as a biological marker in preparing a reagent for diagnosing severe oligoasthenospermia. The fact that the detection frequency of the AKAP4 protein 186th-site generating mass shift -114.04278 can be used for diagnosing the severe oligoasthenospermia is found, so that a new diagnosis and treatment target is provided for the severe oligoasthenospermia.

The invention discloses uses of lysine with + 42.01108 mass shift occurring at a 531 site of ATP5A1 protein as a biomarker in preparation of an oligo / asthenozoospermia diagnostic reagent. The oligo / asthenozoospermia can be diagnosed by the test frequency of + 42.01108 mass shift occurring at a 531 site of ATP5A1 protein, and a new diagnosis and treatment target point is provided for the oligo / asthenozoospermia.

The present invention is drawn to a new diagnosis method for detecting the extent of hepatic steatosis in a patient, in particular in a patient who suffers from a disease involving hepatic steatosis, or who already had a positive diagnosis test of liver fibrosis and / or presence of liver necroinflammatory lesions, by using the serum concentration of easily detectable biological markers. The invention is also drawn to diagnosis kits for the implementation of the method.

The present invention is drawn to a new diagnosis method for detecting the extend of a inflammatory, fibrotic or cancerous disease in a patient, in particular liver fibrosis, in particular in a patient infected with hepatitis C virus, by using the serum concentration of easily detectable biological markers. The invention is also drawn to diagnosis kits for the implementation of the method.

The invention relates to a medical examination and diagnosis method and instrument, in particular to a multi-dimensional electrocardio ultrasonic signal fusion computed tomography imaging system and method based on anatomical orientation. A multi-dimensional ultrasonic cardiac structure and a perfusion image technology are further integrated on the basis of a multi-dimensional electrocardiosignal imaging system and method, and a novel non-invasive platform is provided for recording and evaluating the electro-mechanical signal characteristic and myocardial perfusion characteristic of heart. The method is a unique electrocardio-mechanical function and perfusion synchronized computed tomography imaging method based on anatomical orientation, and the technology is a non-invasive imaging technology for detecting transmural cardiac electrical activity information and mechanical signals. By adopting the medical examination and diagnosis method and instrument, the diagnosis of myocardial diseases such as cardiac hypertrophy, cardiomyopathy, myocardial infarction and myocarditis, the determination of the origin of arrhythmia, and the like can be enhanced, and a brand-new diagnosis and guide treatment tool is provided for rapid real-time diagnosis of heart diseases.

In transmissions of each frame through intermittent transmissions, by performing ultrasonic wave transmissions while increasing a mechanical function step by step, destructions of bubbles of a contrast medium can be induced step by step according to their different sizes. By generating ultrasonic images using the destructions at the respective steps as the sources of echoes, it is possible to provide new ecological information including, for example, information reflecting the dynamics of substances smaller than the red blood cells, the distribution of predatory cells, new diagnosis information, etc.

The invention relates to medical examination and diagnosis methods and instruments, in particular to a multi-dimensional electrocardiosignal imaging system and method. The body surface electric potential mapping technology and the electrocardio vector technology are integrated, a new non-invasive platform is provided for recording the heart-across-myocardium electrical activity information, and in other words, a new non-invasive body surface heart-across-myocardium electrical activity information imaging method and technology which are formed by combining the vector center 0 point galvanic coupling and body surface electric potential mapping technology and are similar to satellite positioning are provided. The non-invasive electrocardio function imaging method and technology for detecting heart-across-myocardium electrocardio activity information with the dissection positioning as a basis are provided. According to the multi-dimensional electrocardiosignal imaging system and method, the arrhythmia reason can be determined, the cardiac muscle diseases such as myocardial hypertrophy, cardiomyopathy, myocardial infarction and myocarditis can be diagnosed, and a brand new diagnosis tool is provided for fast diagnosing the heat diseases in real time.

The invention belongs to the technical field of nuclear power plant equipment reliability, in particular to a method for predicting the fault of three-stage seal of a main pump of a nuclear power plant based on big data analysis, which aims at realizing the prediction of the fault of three-stage seal of the main pump of the nuclear power plant through the correlation and analysis of the operationstate data of the main pump, and facilitating the state maintenance of the power plant. The maintenance mode of nuclear power plant equipments is improved from preventive maintenance to maintenance based on the condition of some equipments. Through the new diagnosis and testing can give accurate defect positioning and valve state trend analysis, valve performance is mainly judged by valve diagnosis, greatly reducing the valve disassembly frequency, saving a lot of materials and human costs. By adopting the method of the invention, sufficient time margin is provided for formulating equipment failure response measures, and unnecessary loss of power plant is avoided.

The invention relates to a method and a system for automatically updating a medical ultrasonic image auxiliary diagnosis system. The method comprises the following steps of: acquiring correction information and a corresponding original focus image, re-training and updating a nodule key frame extraction module and a key frame nodule property judgment module according to the obtained correction information and the corresponding original focus image, and enabling the medical ultrasonic image auxiliary diagnosis system to use the updated system to generate a new diagnosis report. According to thesystem, a closed loop with a continuously updated model is formed, a feedback capture process is provided, correction information given by a doctor is obtained, the system is continuously updated, andthe accuracy of auxiliary diagnosis can be continuously improved.

A diagnosis system and a diagnosis method of a construction machine which enable even a user who has little knowledge about procedures or techniques for diagnosing construction machines to speedily diagnose a construction machine to be diagnosed in a manner suited to the data characteristics of the machine. The diagnosis device (10) acquires diagnosis data from a diagnosis data storage device (30), extracts the data characteristics from the information contained in the diagnosis data, acquires from a diagnosis knowledge storage device (20) diagnosis techniques considered to be effective for the data characteristics, and presents the techniques to the user along with the degree of effectiveness. Then, the user selects a diagnosis technique using the degree of effectiveness and diagnoses the construction machine. Moreover, in order to make the most use of the knowledge about diagnosis stored in the diagnosis knowledge storage device (20), a diagnosis knowledge generation unit (107) classifies common data characteristics by each element of the diagnosis techniques, and stores the classified data characteristics and the elements of the diagnosis techniques as new diagnosis knowledge.

The invention discloses a vehicle diagnosis method and device, equipment and a readable storage medium. The method comprises the following steps of performing authorization check on a vehicle diagnosis file locally stored, and deleting the vehicle diagnosis file exceeding authorization validity; receiving and analyzing a vehicle diagnosis request, and determining a target vehicle model diagnosed by the request; acquiring newest diagnosis file version number of the target vehicle model from a server; acquiring a target diagnosis file corresponding to the newest diagnosis file version number; and diagnosing the vehicle by the target diagnosis file, and acquiring a diagnosis result. In the method, corresponding vehicle terminal files are respectively stored according to the vehicle model, local storage validity is set, cleaning is performed at expiration time, the newest diagnosis filer version number is taken as a bond when vehicle diagnosis is needed, the target diagnosis file is acquired to complete diagnosis, the safety of the vehicle diagnosis file is guaranteed, and the reliability of the vehicle diagnosis result is also ensured.

The invention relates to a medical ultrasonic image computer-aided diagnosis method. The method comprises the following steps: directly acquiring a video signal from medical ultrasonic equipment to obtain ultrasonic images; extracting key frame images containing a focus in the ultrasonic images and carrying out property judgment; performing comprehensive judgment in combination with all the ultrasonic images confirmed as the focus obtained by the scanning, outputting a scanned diagnosis report, and acquiring correction information and corresponding original focus images; re-training and updating a nodule key frame extraction module and a key frame nodule property judgment module according to the obtained correction information and the corresponding original focus images; and generating a new diagnosis report by using an updated model. The method can adapt to a current ultrasonic diagnosis scene, effectively assists a doctor in identifying a focus in the video frame images, forms a report and outputs the report, and improves the diagnosis efficiency and accuracy. The method can also acquire correction information given by a doctor, so that the system is continuously updated, and theaccuracy of auxiliary diagnosis can be continuously improved.

The invention discloses a neospora caninum NcMIC26 antigen and an application thereof. Firstly, the invention discloses neospora caninum NcMIC26 antigen. The amino acid sequence of the antigen is as shown in SEQID NO.1. The invention further discloses an application of recombinant protein of the antigen to construction of a neospora caninum indirect ELISA diagnosis reagent kit. Through screening,a new diagnosis antigen suitable for neospora caninum is obtained, an indirect ELISA reagent kit is established by using the recombinant protein of the antigen as a coating antigen, the operation is simple, quick and efficient, the specificity is good, the sensibility is high, the repeatability is good, the neospora caninum NcMIC26 antigen can be used for detecting neospora caninum infection situation of cattle and can detect positive samples which cannot be detected by common NcSRS2 protein, more accurate detection data can be obtained, and the neospora caninum NcMIC26 antigen has important significance in preventing and treating the neospora caninum.

A user interface (3) for facilitating a computer-aided diagnosis (CAD) includes an image input device (12) that receives and scans the multiple images, and a film feeder (14) transports films from a film developer (15) to the scanner.(12). A multi-image identification input device uses bar code reading, numeric keypad, keyboard, network, and / or mouse to enter multiple image identification prior to image scanning. A display includes an image identification area, case processing status area, and a CAD detection and user modification area. The user can edit CAD results such as accept and remove, and can add new diagnosis results to create a new composite diagnosis result.

The invention relates to a serum surface enhanced Raman spectrum based parotid tumor diagnosis technology, which is a novel technology directed at parotid tumor diagnosis by head and neck tumor surgery and oral and maxillofacial surgery. The technology mainly solves the problem that a conventional biopsy technique cannot be employed for definite diagnosis of parotid tumor patients before operation, replaces the parotid tumor local puncture biopsy technology, avoids complications caused thereby, simultaneously alleviates the work intensity of pathologists, and provides the basis for surgeons to adopt different operative treatment modes according to the benign / malignant nature of tumors. According to the technology, nanoscale gold sol particles are added into parotid tumor patient serum to enhance the intensity of a Raman spectrum so as to obtain a characteristic surface enhanced Raman spectrum of the tumor patient serum. Through analysis of a support vector machine on characteristic spectral data, a differential diagnosis model can be established for identifying different parotid tumors and providing the objective basis for preoperative diagnosis, thus establishing a quick and noninvasive new diagnosis technique.

The invention belongs to the field of biomedicine, and particularly relates to an up-stream open reading frame (uORF) of a phosphatase and tensin homolog (PTEN) gene, and applications of a protein encoded by the uORF. According to the present invention, the 5'UTR of PTEN has a potential 138-base open reading frame (45aa-uORF), wherein the 138-base open reading frame can encode a short peptide having 45 amino acids (named PTEN-45aa), and the short peptide has important effects in the occurrence and development process of tumors; and the new diagnosis, the new treatment method and the new drug screening platform are provided for diseases associated with PTEN expression regulation, particularly gliomas. The invention further provides a polypeptide for treating diseases associated with PTEN expression regulation.

Provided is a diagnostic apparatus easily applied to diagnosis of a small lot product, etc. When measurement data on a measurement object is inputted sequentially, a filter section (408) performs filtering of the measurement data. When new measurement data is employed as diagnosis object data, a statistic processing section (420) updates diagnosis reference data using the new diagnosis object data. A diagnostic section (416) diagnoses the diagnosis object data based on the diagnosis reference data and determines whether an abnormality is present or not. If an abnormality is present, the fact is displayed to a user along with diagnosis results through an UI section (428).

The invention relates to a new diagnosis and treatment target of nasopharynx cancer and application of the new diagnosis and treatment target, and more particularly relates to a VPS11 gene and application that the VPS11 regulates and controls miRNA in treatment of nasopharynx cancer. Nasopharynx cancer tissues and para-carcinoma tissues are analyzed through high-throughput sequencing, mRNA and miRNA transcriptome information is obtained, after analysis, VPS11 gene and miR-363 are screened out and selected to perform fluorescent quantitation PCR verification and target verification, a result shows that the VPS11 gene and miR-363 are closely related to nasopharynx cancer, and VPS11 is a target gene of miR-632 in nasopharynx cancer. Through the invention, a new target is provided for clinical diagnosis and prevention detection of nasopharynx cancer, and has very good application value.

The present invention is drawn to a new diagnosis method for detecting the extent of alcoholic or non-alcoholic steato-hepatitis in a patient, in particular in a patient suffering from a disease involving alcoholic or non-alcoholic steato-hepatitis or who already had a positive diagnosis test of liver fibrosis and / or presence of liver necroinfiammatory lesions, by using the serum concentration of easily detectable biological markers. The invention is also drawn to diagnosis kits for the implementation of the method.

The invention discloses a new human functional gene -LOC344967 which has close relationship with the occurrence and development of NPC. The gene is widely expressed in a plurality of human tissues, NPC biopsy samples and NPC cell line. The apoptosis will occur when the gene is highly expressed in NP69, C666-1, CNE-2, NPC cell line and other cells, which indicates that the gene has great biological function. Gene LOC344967 can be used as a new diagnosis and treatment target for NPC and other cancers.

The invention belongs to the technical field of medicines, and discloses an ERI3 gene and new use of a code thereof. Studies prove that the ERI3 gene and encoded protein thereof not only can be taken as a molecular marker for diagnosing the multiple myeloma, but also can be used as a molecular target for treating the multiple myeloma. Based on the study results, the invention provides a new diagnosis method and treatment means for clinically.

The invention discloses a method for achieving the automobile diagnosis and work project determination in a network questionnaire mode. The method comprises the steps that a car owner logs in an automobile diagnosis cloud server to obtain a questionnaire; the automobile diagnosis cloud server obtains the actual condition information of a car in a mode that the car owner fills in the questionnaire, and correspondingly searches and analyzes an automobile diagnosis cloud server database according to the car condition information in the questionnaire; the diagnosis result and work project are correspondingly extracted if there is the same car condition information, and the server correspondingly pushes the diagnosis result to a mobile terminal of the car owner; a mobile terminal of a maintainer is correspondingly used for diagnosis and analysis of the car condition information if there is no identical car condition information, and a new diagnosis result and work project are generated; and the correspondingly server pushes the diagnosis result to the mobile terminal of the car owner, and completes the request of work project maintenance. The method greatly meets the demands for the timely and accurate understanding of the actual car conditions during car diagnosis, and avoids the excessive maintenance.

The invention discloses a molecular marker-EAPP gene for early diagnosis of the Alzheimer disease. An experimental result shows that the mRNA level of the EAPP gene in blood of the patient suffering from the Alzheimer disease is remarkably lower than that of normal people, so that whether a tested person has the risk of the Alzheimer disease or not or whether the tested person has suffered from the Alzheimer disease or not is judged by determining the expression level of the EAPP gene in the blood of the tested person. The EAPP gene can be used for preparation and application for the patient suffering from the Alzheimer disease or the crowd with the high Alzheimer disease risk so as to be used for treating the Alzheimer disease or preventing the Alzheimer disease. The new diagnosis method is provided for diagnosing the Alzheimer disease clinically and the new candidate medicine is provided for treating the Alzheimer disease.