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359 results about "Needle Free Injection" patented technology

Needle-free injection is a method of injecting using a jet injector device like Comfort-in™, which injects liquid medicine, anaesthesia, vitamins, or other liquid injectables through the skin and into the subcutaneous tissue, via high pressure.

Intradermal delivery of active agents by needle-free injection and electroporation

Methods are proved for introducing a biologically active agent into cells of a subject by introducing the agent in a form suitable for electrotransport into a region of tissue of the subject using one or more needle-free injectors, and applying a pulsed electric field to the region of tissue, thereby causing electroporation of the region of tissue. The combination of needle-free injection and electroporation is sufficient to introduce the agent into cells in skin, muscle or mucosa. For example, the region of tissue can be contacted with two oppositely charged injectors, one acting as the donor electrode and one acting as the counter electrode, or a single injector and one or more electrodes can be used. In addition, needle-free injection may be used in combination with suitable non-invasive electrode configurations. The active agents delivered into cells using the invention method can be small molecules, polynucleotides, polypeptides, and the like.
Owner:ONCOSEC MEDICAL

Needle-less injector and method of fluid delivery

A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human.
Owner:PHARMAJET INC

Needleless syringe

A method of distributing particles in a flow of gas and a needleless syringe for use in the needleless injection of particles into the skin or mucosa of a vertebrate subject are disclosed. The syringe includes a convergence which reduces pressure of the gas flowing in the gas flow path due to the Venturi effect such that particles initially located outside of the gas flow path are drawn into the gas flow path under the action of the reduced pressure and become entrained in the gas. An exit nozzle accelerates the particles so entrained. In another aspect of the invention, there is provided a method of creating a gas flow in a needleless syringe which comprises flowing gas through a first convergence into a chamber to form a transsonic gas jet in the chamber and passing the gas jet from the chamber into a second convergence and along the nozzle.
Owner:POWDER PHARM INC

Method and apparatus for filling or refilling a needle-less injector

Devices and methods are described for filling or refilling a needle-less injector. A coupling device is attached to a vessel, and mated to the dispensing end of a needle-less injector. A volume of fluid may be transferred via the coupling device, from the vessel to the injector. Air may be removed from the injector prior to the injector, vessel, and coupling device being separated from one another. In alternate embodiments, the vessel may include filling equipment capable of filling or refilling multiple needle-less injectors simultaneously, in series, or both. In other embodiments, a coupling device may be used to withdraw a fluid from a storage vial into a vessel for filling a needle-less injector. A storage vial may alternately contain a product, and a fluid may be introduced therein via a coupling device to create a mixture, which may be subsequently withdrawn into a vessel for filling a needle-less injector.
Owner:PENJET CORP

Method and apparatus for needle-less injection with a degassed fluid

InactiveUS20040035491A1Minimize and avoid formationAmpoule syringesJet injection syringesNeedle Free InjectionProduct gas
Apparatuses and methods are described for administering a needle-less injection of a degassed fluid. Prior to filling, or after filling but prior to administration of a needle-less injection, gas is removed from the fluid. A needle-less injection may then be performed with a reduced risk of discomfort to the recipient of the injection and with lower potential for the creation of a subdermal hematoma as a result of the injection. A wide variety of needle-less injectors may be used in accordance with various embodiments of the present invention.
Owner:PENJET CORP

Medical fluid coupling port with guide for reduction of contamination

This invention provides a female medical coupling port with an integrated port guide to enable more accurate and precise coupling of a male port coupling (such as the cannula of a syringe) and to prevent port exposure to non-sterile objects. The male and female ports can be arranged according to standard dimensions for male and female luer taper fittings recognized by ANSI and by ISO. This guide-shielded port is usable with the standard ANSI and ISO male cannula widely used in the medical field. In an embodiment the female port is used in medical fluid systems to receive a blunt male cannula, such as those found in the luer lock fitting of needle-less syringes and IV tubing systems to establish a mechanical coupling. Female ports allow coupling of devices (e.g. syringes and IV tubing) to a variety of medical applications including stopcocks, minimum fluid displacement medical couplings, female-to-female adapters, port dead-end caps, IV extension sets, pressure-monitoring devices, etc. The port guide can be constructed as a unitary part of the port, or can be a retrofittable structure that is either snapped into place on, for example, a female port stem, or slid onto a port, such as a minimum displacement fluid coupling. Appropriate drain ports can be provided in the port guide to prevent capture of excess fluid.
Owner:DARTMOUTH HITCHCOCK CLINIC
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