31 results about "Alternative strategy" patented technology

Accelerated heating of automotive exhaust system components is effected by controlling the application of supplemental electrical loads to the vehicle electrical system thereby increasing engine load and increasing exhaust heat. Alternative strategies are disclosed for implementing the invention through control of electrical and engine management system parameters.

This disclosure relates generally to the facile and selective mono-perfluoro and -polyfluoroarylation of Meldrum's acid to generate a versatile synthon for highly fluorinated alpha-phenyl acetic acid derivatives which provide straightforward access to fluorinated building blocks. The reaction takes place quickly and all products were isolated without the need for chromatography. An embodiment provides an alternative strategy to access alpha-arylated Meldrum's acids which avoids the need for aryl-Pb(IV) salts or diaryliodonium salts and provides access to the tertiary product which was not previously synthetically accessible. The synthetic versatility and utility of the Meldrum's acid products is demonstrated by subjecting the products to several derivatizations of the Meldrum's acid products as well as photocatalytic hydrodefluorination which provide access to difficult but valuable synthetic targets such as multifluorinated aromatics.

A family of hedge funds, serving as “feeder funds”into underlying single-manager hedge funds, formed to provide smaller investors with the ability to allocate and reallocate assets among alternative strategies, and this basic structure combining interrelated systems and methods for offering, redeeming, exchanging, valuing, reporting and servicing the same is a new approach. The system and methods described herein provide investors having less than ultra-high net worth portfolios with access to hedge funds and the potential valuable diversification to an overall portfolio, and the ability to customize their portfolio of hedge funds to their individual needs and adjust such portfolio over time as seen fit in light of changing financial needs and market conditions. This invention gives a wide range of investors access to hedge funds, creating economic value using a new source of stable investor capital for hedge fund managers, a value shared with investors through reduced costs.

The present invention provides a monitoring and management method and system based on a monitoring system. The method includes the following steps: monitor each monitoring device that is abnormal in the central server, and determine the strategy according to the preset alternative priority, and obtain the corresponding After monitoring the alternative priorities corresponding to the monitoring devices, the monitoring devices send broadcast messages to each other, wherein the broadcast messages carry the alternative priorities; each monitoring device that monitors that the central server is abnormal receives the broadcast After the message, compare the alternative priority determined by itself with the alternative priority carried in the received broadcast message, and determine that the monitoring device corresponding to the highest alternative priority is the target monitoring device; the target monitoring device follows the preset monitoring strategy, Control and monitor other monitoring equipment that is abnormal in the central server, and build a system with self-construction capabilities, which can greatly improve the safety factor of security, and will not cause the system as a whole to fail due to damage to some links.

The present invention relates to methods and compositions for determining the likelihood that a subject suffering from a cancer will benefit from treatment with a MEK inhibitor. It also relates to methods of treatment based on such determination. The invention is based, at least in part, on the discoveries that DDX43 mRNA and protein are expressed at high levels in biopsies from "non-responder" UM patients and that selumetinib-resistant cell lines showed high DDX43 expression which correlated with increased expression and activity of RAS. It was found that KRAS and HRAS but not NRAS, mediated expression of pERK and pAKT, bypassing oncogenic GNAQ. The invention is further based on the discovery that selumetinib-resistant cells became sensitive to AKT inhibition, suggesting alternative strategies for the treatment of cancer patients with acquired resistance to MEK inhibitors.

The invention discloses a microgrid-based dynamic strategy simulation and optimization method. The microgrid-based dynamic strategy simulation and optimization method comprises the steps of building amicrogrid running strategy library to store and manage control strategies of a microgrid in different running environments; dividing control time frames during the running process of a microgrid system, and timely selecting an alternative strategy set for running at a next time frame from the strategy library according to states of each power supply and a load in the microgrid; issuing the selected strategy set to a microgrid simulation model built on the basis of MATLAB, performing simulation calculation on the running state of the microgrid, and selecting the optimal running strategy as therunning strategy of the next time frame by comparing and analyzing a result of the simulation system under each alternative strategy; and comparing and analyzing the strategy running result and the simulation calculation result, improving and optimizing the employed strategy by a genetic algorithm, and favorably achieving the optimal effect during application after iteration.