60results about How to "Rapid and reliable" patented technology

Provided are devices, and related methods, for controlling curvature of an array of optical components on, embedded, or partially embedded in, a deformable substrate. The array of optical components, in an aspect, comprises a deformable substrate having a contact surface and an array of mechanically interconnected optical components supported by the contact surface. An actuator is operably connected to the contact surface, wherein the actuator variably controls a curvature of said contact surface. The contact surface may have a curvature that spans concave to convex, which is tunable. In an aspect, the array of optical components is part of on optical device, such as a camera with a continuously adjustable zoom whose focus is maintained by adjusting a photodetector array curvature. In an aspect, the method is adjusting the curvature of a substrate that supports the array of optical components by applying a force to the substrate.

Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.

The invention provides a method of tracking, identifying, and/or sorting classes or subpopulations of molecules by the use of oligonucleotide tags. Oligonucleotide tags of the invention each consist of a plurality of subunits 3 to 6 nucleotides in length selected from a minimally cross-hybridizing set. A subunit of a minimally cross-hybridizing set forms a duplex or triplex having two or more mismatches with the complement of any other subunit of the same set. The number of oligonucleotide tags available in a particular embodiment depends on the number of subunits per tag and on the length of the subunit. An important aspect of the invention is the use of the oligonucleotide tags for sorting polynucleotides by specifically hybridizing tags attached to the polynucleotides to their complements on solid phase supports. This embodiment provides a readily automated system for manipulating and sorting polynucleotides, particularly useful in large-scale parallel operations, such as large-scale DNA sequencing, mRNA fingerprinting, and the like, wherein many target polynucleotides or many segments of a single target polynucleotide are sequenced simultaneously.

An improved vehicle running board construction and method of making same including a hollow metal support pipe with an elongated mid-section step portion adapted in vehicle-mounted orientation to extend generally parallel to and adjacent a sill of a vehicle door that provides access to a passenger or freight compartment of the vehicle. An elongate mounting opening is formed in an upwardly facing exterior surface area of the pipe mid-section. A support plate has a plurality of transverse trusses arranged in spaced apart relation in a longitudinally extending row and straddling the opening side edges and resting thereon for support. A plurality of spacer webs are individually interposed between and joined to longitudinally adjacent pairs of the trusses and support at each of their longitudinally opposite ends, a resilient spring finger catch oriented to underlie an associated one of the pipe opening side edges. Each finger catch has a free end resiliently engaging an interior surface of the pipe for holding the step plate against upward release from the pipe. A step plate is mounted on and covers the support plate as well as the mounting opening of the pipe. The step plate has a generally flat planar central step tread portion with an undersurface bearing upon the support plate trusses. The step plate also has downwardly extending side flanges respectively extending outwardly of and downwardly past the pipe opening side edges and terminating at free end edges that preferably resiliently engage the exterior surface of the pipe. A plurality of retaining barbs extend downwardly from the step plate undersurface into snap lock tang engagement with associated receiving slot anchor tabs provided in the trusses for holding the step plate on the support plate, and vice versa.

An air blowing portion blows air to the end of sheets supported by a lifting and lowering tray. The sheets blown up by the air from the air blowing portion are sucked and conveyed by a sucking and conveying portion. The sheets are preliminarily blown up above the suckable rang. Then, the sheets are lowered to the suckable range before a sucking and conveying operation is started. In the above operation, the tray is lifted, and thereafter the tray is lowered until the sheets reach the suckable range while repeating a step operation of performing a lowering operation and a stop operation based on detection of the upper surface of the sheets by a sheet detecting mechanism.

A sealed contact device capable of maintaining a function for drawing a generated arc to disappear rapidly and reliably for a long period. An electromagnetic relay includes a housing, a stationary contact and a moving contact which are disposed opposite to each other in the housing, and a pair of permanent magnets and disposed opposite to the stationary contact and the moving contact. An arc generated between the stationary contact and the moving contact is drawn due to a current conducting between the stationary contact and the moving contact and magnetic forces of the permanent magnets. An arc shield member is disposed in a position in which an arc in the housing is induced.

The present invention is in the field of nucleic acid-based diagnostic assays. More particularly, it relates to methods useful for the “diagnostic sequencing” of regions of sample nucleic acids for which a prototypic or reference sequence is already available (also referred to as “re-sequencing”), or which may be determined using the methods described herein. This diagnostic technology is useful in areas that require such re-sequencing in a rapid and reliable way: (i) the identification of the various allelic sequences of a certain region/gene, (ii) the scoring of disease-associated mutations, (iii) the detection of somatic variations, (iv) studies in the field of molecular evolution, (v) the determination of the nucleic acid sequences of prokaryotic and eukaryotic genomes, (vi) identifying one or more nucleic acids in one or more biological samples', (vii) and determining the expression profile of genes in a biological sample and other areas.

A shelving system for use with a load cell has a frame, to which the load cell is mounted, and a rack residing within the frame and having a load cell proximity surface supported on the load cell by a pivotal contact element. The rack is stabilized by an anti-sway system having three lever arms connected between the frame and the rack and spaced apart from the load cell proximity surface. A first and a second lever arm are parallel and spaced apart from each other, and extend parallel to two faces of the rack, while a third lever arm extends substantially normal to the first and the second lever arms. A fourth lever arm can be provided, located in close proximity to the load cell proximity surface and extending parallel to at least one of the other lever arms.

The present invention provides a method for detecting acoustic shock in an audio input signal (s(t)), comprising the steps of monitoring the input signal (s(t)) in the time-domain. Thereby detecting the signal floor (Sn), detecting the peak level of the input signal (L), detecting the attack time of the input signal (t1-t0), detecting the duration of the input signal (T). Based on those detections, determining a shock contrast level (SCL) as difference between the peak level (L) and the signal floor (Sn), determining a shock index (SI) by use of a shock index normalization constant (σ) and comparing the shock contrast level (SCL) and the shock index (SI) with respective thresholds and indicating an acoustic shock if one or both thresholds are exceeded. Thus, the present method provides a quick and reliable shock detector that operates in the time-domain. The shock detection takes place with zero time delay, or even predicts the shock before it fully goes through the signal processing.

A peeling machine according to the present invention includes a cutter head and a feed mechanism having upper and lower feed rollers, and the feed mechanism includes a first holder that supports the lower feed roller, a second holder that supports the upper feed roller, a roller opening/closing driving mechanism, a synchronizing mechanism that has a pinion disposed in the same vertical plane as axes of the both feed rollers and first and second racks, and a grasping-force applying cylinder that applies a downward work grasping force to the second holder.

In an apparatus for separating parts arranged for example in at least two adjacent rows and including a transfer device, which is provided with at least two holding elements which pick up the parts in a first position and deposit them in a second position 5b, means are provided by which the distance at which the holding elements are disposed adjacent one another is changeable during the transport of the parts from the first position to the second position.