The invention relates to a tomato multifunctional medical fertilizer. The medical fertilizer is characterized by comprising, by weight, 33.1-33.4 parts of mushroom residue, 32-34 parts of urea, 19.4-20 parts of potassium sulfate, 7.1-7.5 parts of monoammonium phosphate, 2-2.5 parts of sodium polyacrylate, 0.6-0.8 part of copper sulfate, 0.4-0.5 part of potassium permanganate, 0.35-0.4 part of aluminum Ridomil, 0.29-0.3 part of thiophanate methyl, 0.29-0.3 part of carbendazim, 0.18-0.2 part of agricultural streptomycin sulfate and 0.08-0.1 part of compound sodium nitrophenolate. The medical fertilizer integrates the nutritive action of mushroom residue, urea, potassium sulfate and monoammonium phosphate, the water-retaining action of sodium polyacrylate, the disease-preventing action of copper sulfate, potassium permanganate, aluminum Ridomil, thiophanate methyl, carbendazim and agricultural streptomycin sulfate, and the growth-promoting action of compound sodium nitrophenolate together, so that problems such as soil nutrient imbalance, reduced water-retaining capacity, serious soil-borne diseases and the like of tomato are solved. The medical fertilizer is applied to fields such astomato fertilizer production, soil nutrient supplement in tomato planting, tomato disease prevention and treatment, and the like.