363results about "Particle separator tube details" patented technology

An integrated analytical device is described. The device includes a plurality of components which are initially mounted or provided on support submounts. The submounts are then packaged onto a microbench, with the alignment of the submounts relative to the microbench being determined by alignment features provided on the microbench.

The invention belongs to the technical field of mass spectrometry and particularly relates to a cascade mass spectrometry method performed in an ion trap mass analyzer. The cascade mass spectrometry method performed in the ion trap mass analyzer specifically comprises three stages of ion selective segregation, collision induction dissociation and mass scanning and analyzing. According to the cascade mass spectrometry method performed in the ion trap mass analyzer, in the stage of collision induction dissociation, by changing the period of a radio frequency signal, namely changing the frequency of radio-frequency voltage loaded on an ion trap, parent ions with a certain mass-to-charge ratio undergo resonance excitation so as to obtain energy. The high-energy ions which undergo resonance excitation collide with neutral molecules in the ion trap and are dissociated, outcome ions are generated, and the cascade mass spectrometry is achieved. The cascade mass spectrometry method performed in the ion trap mass analyzer has the advantages that only arrangement of software can be used for changing the scanning period of the stage of collision induction dissociation in order to achieve collision induction dissociation, and thus, an experiment device and a method of cascade mass spectrometry can be obviously simplified.

Particular aspects provide novel methods for analysis of ion populations, the methods comprising filtering and selecting an ion population using a low-field dual-gate ion mobility spectrometer comprising a drift tube, the spectrometer operating at a pressure of at least 100 Torr, to provide mobility-selected ions. Certain aspects comprise: (i) subsequently accumulating the low-field selected ions in an ion trap (e.g., an MS ion trap) and mass spectrometry analysis; (ii) introducing the low-field selected ions into a high-field ion mobility spectrometer for separating thereby (optionally followed by mass spectrometry); and (iii) introducing the low-field selected ions into an ion trap mass spectrometer, and subsequently into a second low-field ion mobility spectrometer (e.g., a non-dual gate spectrometer operating at less than about 100 Torr). Additional aspects provide novel apparatus and combination thereof for performing the disclosed methods.

A method for analysing ions according to their mass-to-charge ratio and mass spectrometer for performing the method, comprising directing a collimated ion beam along an ion path from an ion source to an ion detector, causing a portion of the ion beam to contact one or more surfaces prior to reaching the ion detector, wherein the method comprises providing a coating on and / or heating the one or more surfaces to reduce variation in their surface patch potentials. The method is applicable to multi-reflection time-of-flight (MR TOF) mass spectrometry.