The invention discloses a three-dimensional horizontal geological section map manufacturing method and applications of the three-dimensional horizontal geological section map manufacturing method. The method comprises the steps of obtaining wild geological raw data according to relevant correlation technical standard requirements of energy mineral resource geology and engineering geology, wherein the wild geological raw data comprise but not limited to drilling geological data, drilling point three-dimensional position information, geophysical exploration information and relevant indoor and outdoor testing data. The total number of the steps is ten. The method is applied to engineering geological map manufacturing and energy mineral resource geological map manufacturing, and geological mapping result expressing in geological mapping in the engineering geology and the energy mineral resource geology, wherein the geological mapping result expressing comprises but not limited to relevant mapping result expressing in the links of engineering geological mapping, designing, analyzing, constructing, monitoring and running and relevant mapping result expressing in the links of energy mineral resource planning, mapping, designing, monitoring, exploiting, running and repairing.