The embodiment of the invention provides a gene detection method, a model training method, a device, equipment and a system. The gene detection method comprises the following steps: acquiring to-be-processed gene data, wherein the average number of gene segments corresponding to each position in the to-be-processed gene data is smaller than or equal to a preset threshold value; inputting the to-be-processed gene data into a feature generation network layer for feature extraction operation to obtain gene features corresponding to the to-be-processed gene data and enhanced features corresponding to the gene features; and inputting the to-be-processed gene data and the enhanced features into a gene identification network layer for gene detection operation to obtain a detection result. According to the technical scheme provided by the embodiment, feature extraction operation is carried out through low-depth gene data, the gene features and the enhanced features corresponding to the gene features are obtained, and detection operation is carried out based on the enhanced features, so the accuracy of a gene detection result is ensured, and the data processing cost and the data processing amount are also reduced.