The invention discloses low-temperature therapeutic equipment using a coolant. The therapeutic equipment comprises a refrigerating device, a one-way valve, a coolant storage tank, a coolant recovery tank, an air compressor, an air storage tank, an adjusting valve, a control system, a low-temperature probe and the like, wherein the air compressor compresses air into certain high pressure and stores the compressed air in the air storage tank; when the coolant, namely low-temperature silicone oil, refrigerated by the refrigerating device flows into the storage tank through the one-way valve and is accumulated to a certain amount, a liquid level sensor transmits a signal to a programmable controller to open the adjusting valve so as to charge the compressed air into the storage tank; the programmable controller controls the opening of the adjusting valve through a pressure signal detected by a pressure sensor, so that the low-temperature silicone oil is squeezed out of the storage tank bya corrugated pipe at a certain flow rate to flow to the low-temperature probe, and the silicon oil flowing out from the low-temperature probe returns to the recovery tank. The equipment can be applied to cold therapy on diseased tissues.