The invention discloses a 3D gradient
spin echo diffusion imaging method for
inversion recovery preparation, a medium and equipment. The method comprises the following steps of firstly, in an
inversion recovery preparation module, applying 180-degree inversion
radio frequency pulse, and setting corresponding
inversion recovery time to inhibit
cerebrospinal fluid and
free water signals; secondly, embedding a pair of trapezoidal cosine oscillation gradients or pulse gradients into 90-degree x-180-degree y-90-degree-x
radio frequency pulses through a
diffusion coding module, and separating
diffusion coding from
signal acquisition; then, inhibiting a fat
signal by using a
fat saturation module; and finally, collecting signals by adopting a 3D gradient
spin echo reading mode. The time and the
signal-to-
noise ratio of magnetic
resonance diffusion imaging are improved, accurate measurement of
brain tissue diffusion magnetic
resonance signal time dependence is facilitated, the effect is especially obvious for a brain area which is near a
ventricle and is influenced by the
cerebrospinal fluid due to a partial
volume effect, and the clinical transformation of a time-dependent diffusion magnetic
resonance technology is effectively promoted.