48 results about "Conduction delay" patented technology

A system and method for estimating optimal atrioventricular delay values for use in pacing the ventricles. Both the intrinsic inter-atrial conduction delay and the intrinsic atrioventricular conduction delay are determined for the patient and then the preferred atrioventricular pacing delay is derived therefrom. By taking into account intrinsic inter-atrial delay along with intrinsic atrioventricular delay, a more reliable estimate of the true optimal atrioventricular delay values for the patient can be achieved than with techniques that only take into account intrinsic atrioventricular delay values. In one example, the technique uses intracardiac electrogram (IEGM) signals and surface electrocardiogram (EKG) signals and hence can be performed by an external programmer without requiring Doppler echocardiography or other cardiac performance monitoring techniques. In another example, wherein the implanted device is equipped with a coronary sinus lead, the technique uses only IEGM signals and hence can be performed by the device itself.

The bi-ventricular implantable pulse generator described and depicted herein enables hemodynamic efficiencies for patients suffering from intraventricular conduction delays or conduction blockage. The pulse generator effectively overcomes such conduction delay or block (e.g., left bundle branch block, “LBBB,” or right bundle branch block, “RBBB”) by delivering a novel form of cardiac resynchronization therapy (CRT). Specifically, a single ventricular pre-excitation pacing stimulus is triggered from an atrial event (e.g., intrinsic or evoked depolarization). The triggering event may emanate from the right atrium (RA) or the left atrium (LA). A single ventricular pre-excitation pacing stimulus is delivered prior to the intrinsic depolarization of the other ventricle and thus promotes intraventricular electromechanical synchrony during CRT delivery.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing. In one example, optimal atrio-ventricular and interventricular pacing delay values are determined for pacing the heart of the patient based, in part, on a measured inter-atrial conduction delay. Atrio-ventricular conduction delays are then measured within the patient. The atrio-ventricular pacing delays are compared with the measured atrio-ventricular conduction delays. If the atrio-ventricular pacing delays are less than the measured atrio-ventricular conduction delays, biventricular pacing is delivered using the atrio-ventricular pacing delay and the interventricular pacing delay. However, if the atrio-ventricular pacing delays are not less than the corresponding atrio-ventricular conduction delays, as can occur if the inter-atrial conduction delay is large, then alternative pacing regimes are selectively enabled, such as monoventricular pacing in the chamber having the longer conduction delay value, biventricular pacing with negative hysteresis, or biventricular pacing with pacing delays reduced using predetermined offset values.

An exemplary method includes delivering a cardiac resynchronization therapy using an atrio-ventricular delay parameter and an interventricular delay parameter, measuring an atrio-ventricular conduction delay, measuring an interventricular conduction delay, assessing heart failure and / or cardiac resynchronization therapy performance based at least in part on the measured atrio-ventricular conduction delay and the measured interventricular conduction delay and determining at least one of an atrio-ventricular delay parameter value and an interventricular delay parameter value based at least in part on the measured atrio-ventricular conduction delay and the measured interventricular conduction delay. Other exemplary technologies are also disclosed.

An atrioventricular delay (AVD) for cardiac pacing therapy is determined based, at least in part, on one or more cardiac activation signals sensed using body-implantable electrodes providing non-local sensing. A conduction delay is estimated using a non-local cardiac activation signal and the AVD is determined based on the conduction delay. Estimating the conduction delay may involve measuring a P-wave width or measuring a QRS complex width of the non-local signal. If multiple signals are sensed, the conduction delay may be estimated from a selected signal or may be estimated by forming a representative signal such as through averaging or other methods. The AVD may be determined as a function of the estimated conduction delay.

Techniques are provided for use with implantable cardiac stimulation devices equipped for multi-site left ventricular (MSLV) cardiac pacing. Briefly, intraventricular and interventricular conduction delays are detected for paced cardiac events. Maximum pacing time delays are determined for use with MSLV pacing where the maximum pacing time delays are set based on the conduction delays to values sufficient to avoid capture problems due to wavefront propagation, such as fusion or lack of capture. MSLV pacing delays are then set to values no greater than the maximum pacing delays and cardiac resynchronization therapy (CRT) is delivered using the MSLV pacing delays. In an example where an optimal interventricular pacing delay (VV) is determined in advance using intracardiac electrogram-based or hemodynamic-based optimization techniques, the optimal value for VV can be used as a limiting factor when determining the maximum MSLV pacing time delays.

Various techniques are provided for assessing the reliability of left atrial pressure (LAP) estimates made by an implantable medical device based on impedance values or related electrical values. In one example, various cardioelectric and cardiomechanical parameters are used to corroborate LAP estimation in circumstances where the LAP estimates deviate from an acceptable, satisfactory or otherwise healthy range. The cardioelectric parameters include, e.g.: ST elevation; heart rate (HR); heart rate variability (HRV); T-wave alternans (TWA); QRS waveform parameters; P-wave duration; evoked response (ER) parameters; and intrinsic PV / AV / VV conduction delays. The cardiomechanical parameters include, e.g.: heart rate turbulence (HRT); cardiogenic impedance signals; heart sounds; and non-LAP blood pressure measurements, such as aortic pressure measurements. The device compares the cardioelectric and cardiomechanical parameters against corresponding baseline values to determine whether variations in the parameters corroborate the LAP estimates. If not, the LAP estimates are selectively cancelled or suspended, or the overall procedure is re-calibrated.

The present invention enables hemodynamic efficiencies for patients suffering from intraventricular conduction delays or conduction blockage. The invention effectively overcomes such conduction delay or block (e.g., left bundle branch block, “LBBB,” or right bundle branch block, “RBBB”) by delivering a novel form of cardiac resynchronization therapy (CRT). Specifically, a single ventricular pre-excitation pacing stimulus is triggered from an atrial event (e.g., intrinsic or evoked depolarization). The triggering event may emanate from the right atrium (RA) or the left atrium (LA). A single ventricular pre-excitation pacing stimulus is delivered prior to the intrinsic depolarization of the other ventricle and thus promotes intraventricular electromechanical synchrony during CRT delivery.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing using a multi-pole left ventricular (LV) lead. In one example, a single “V sense” test is performed to determine intrinsic interventricular conduction time delays (Δn) between the RV electrode and each of the LV electrodes of the multi-pole lead. Likewise, a single “RV pace” test is performed to determine paced interventricular conduction time delays (IVCD_RLn) between the RV electrode and each of the LV electrodes. A set of “LV pace” tests is then performed to determine paced interventricular conduction time delays (IVCD_LRn) between individual LV electrodes and the RV electrode. Optimal or preferred interventricular pacing delays are determined using the intrinsic interventricular conduction delay (Δn) values and a set of interventricular correction terms (εn) determined from the results of the RV pace test and the set of LV pace tests. With these techniques, overall test time can be reduced.

Techniques are provided for estimating optimal atrioventricular delay values for use in pacing the ventricles. Both the intrinsic inter-atrial conduction delay and the intrinsic atrioventricular conduction delay are determined for the patient and then the preferred atrioventricular pacing delay is derived therefrom. By taking into account intrinsic inter-atrial delay along with intrinsic atrioventricular delay, it is believed that a more reliable estimate of the true optimal atrioventricular delay values for the patient can be achieved than with techniques that only take into account intrinsic atrioventricular delay values. In one example, the technique uses intracardiac electrogram (IEGM) signals and surface electrocardiogram (EKG) signals and hence can be performed by an external programmer without requiring Doppler echocardiography or other cardiac performance monitoring techniques. In another example, wherein the implanted device is equipped with a coronary sinus lead, the technique uses only IEGM signals and hence can be performed by the device itself.

Methods to identify and risk stratify disease states, cardiac structural defects, functional cardiac deficiencies induced by teratogens and other toxic agents, pathological substrates, conduction delays and defects, and ejection fraction using single channel biological data obtained from the subject. A modified Matching Pursuit (MP) algorithm may be used to find a noiseless model of the data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to characterize the cardiac system. In another method, space-time domain is divided into a number of regions (which is largely determined by the signal length), the density of the signal is computed in each region and input to a learning algorithm to associate them to the desired cardiac dysfunction indicator target.

Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP.

Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.

Techniques are provided for estimating left atrial pressure (LAP) or other cardiac performance parameters based on measured conduction delays. In particular, LAP is estimated based interventricular conduction delays. Predetermined conversion factors stored within the device are used to convert the various the conduction delays into LAP values or other appropriate cardiac performance parameters. The conversion factors may be, for example, slope and baseline values derived during an initial calibration procedure performed by an external system, such as an external programmer. In some examples, the slope and baseline values may be periodically re-calibrated by the implantable device itself. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP or other cardiac performance parameters. Still further, techniques are described for estimating conduction delays based on impedance or admittance values and for tracking heart failure therefrom.

The invention discloses a distributed control system and a distributed control method, in particular to a multi-robot control synchronization system and a multi-robot control synchronization method based on distributed clocks. The multi-robot control synchronization system comprises a master controller and a plurality of slave controllers, wherein the master controller is used for acquiring link structures of the plurality of slave controllers so as to determine a network topology of the distributed control system, completing initialization of the plurality of slave controllers, acquiring timestamp information of the plurality of slave controllers, calculating conduction delay and initial deviation of each slave controller relative to the master controller separately, and judging whether the plurality of slave controllers are synchronized with the master controller; and if so, the master controller sets a synchronization cycle of the distributed control system, and data exchange and clock drift compensation are conducted between the master controller and the plurality of slave controllers within the synchronization cycle. The invention further provides the distributed control method. Through effectively improving the utilization rate of network bandwidth and reducing complexity of connection between control systems, the jitter among the controllers is reduced to the minimum.

An LED tube lamp is disclosed. The LED tube lamp includes a lamp tube, a first external connection terminal and a second external connection terminal coupled to the lamp tube and for receiving an external driving signal, a rectifying circuit coupled to the first external connection terminal and the second external connection terminal and configured to rectify the external driving signal to produce a rectified signal, a filtering circuit coupled to the rectifying circuit and configured to filter the rectified signal to produce a filtered signal, an LED module coupled to the filtering circuit and configured to receive the filtered signal for emitting light; and a conduction-delaying circuit coupled to the rectifying circuit and comprising a conduction-delaying device, wherein the conduction-delaying circuit is configured such that when the external driving signal is initially input to the LED tube lamp, the conduction-delaying device is in an open-circuit state, and then the conduction-delaying device will enter a conducting state when voltage across the conduction-delaying device exceeds the conduction-delaying device's trigger voltage value, wherein the conducting state of the conduction-delaying device causes the LED module to conduct current for emitting light.

A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various embodiments, values for atrio-ventricular delay intervals are each computed as a function of an intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. Examples of the parameter reflective of the interventricular conduction delay include QRS width and interval between right and left ventricular senses.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing. In one example, optimal atrio-ventricular and interventricular pacing delay values are determined for pacing the heart of the patient based, in part, on a measured inter-atrial conduction delay. Atrio-ventricular conduction delays are then measured within the patient. The atrio-ventricular pacing delays are compared with the measured atrio-ventricular conduction delays. If the atrio-ventricular pacing delays are less than the measured atrio-ventricular conduction delays, biventricular pacing is delivered using the atrio-ventricular pacing delay and the interventricular pacing delay. However, if the atrio-ventricular pacing delays are not less than the corresponding atrio-ventricular conduction delays, as can occur if the inter-atrial conduction delay is large, then alternative pacing regimes are selectively enabled, such as monoventricular pacing in the chamber having the longer conduction delay value, biventricular pacing with negative hysteresis, or biventricular pacing with pacing delays reduced using predetermined offset values.

The invention discloses a three-level dead time compensation method based on current vector equivalence, so as to solve problems such as system harmonic increase and voltage distortion caused due to dead time effects when SVPWM modulation is adopted for modulation by a three-level inverter. According to the compensation method, through judging the direction of the three-phase current, error voltage generated due to conduction delay of a power device in the case of state switching of a three-phase bridge arm is obtained, synthesis in a two-phase static coordinate system is carried out, and error voltage based on current vector equivalence is obtained. On the basis, a voltage vector opposite to the equivalence is compensated, a reference instruction in the two-phase static coordinate system is rebuilt, dead time effects are offset, the SVPWM modulation output dead time us compensated, and system performance is effectively enhanced.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing using a multi-pole left ventricular (LV) lead. In one example, a single “V sense” test is performed to determine intrinsic interventricular conduction time delays (Δn) between the RV electrode and each of the LV electrodes of the multi-pole lead. Likewise, a single “RV pace” test is performed to determine paced interventricular conduction time delays (IVCD_RLn) between the RV electrode and each of the LV electrodes. A set of “LV pace” tests is then performed to determine paced interventricular conduction time delays (IVCD_LRn) between individual LV electrodes and the RV electrode. Optimal or preferred interventricular pacing delays are determined using the intrinsic interventricular conduction delay (Δn) values and a set of interventricular correction terms (εn) determined from the results of the RV pace test and the set of LV pace tests. With these techniques, overall test time can be reduced.

A methods and devices for capture detection are based on sensing a propagated depolarization from a contralateral cardiac chamber. An intersite sensing interval is determined based on an intersite pacing delay and an intersite conduction delay associated with first and second pacing sites. Pacing pulses are delivered to the first pacing site and the second pacing site, the pacing pulses separated in time by the intersite pacing delay. An intersite sensing interval is timed. The process includes sensing, during the intersite sensing interval, at the first pacing site for a depolarization propagated to the first pacing site from the second pacing site. It a depolarization propagated from the second pacing site is not sensed, then capture of the first and second pacing sites is detected.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing, particularly during atrial fibrillation. In one example, during a V sense test for use in optimizing ventricular pacing, the implantable device determines relative degrees of variation within antecedent and succedent intervals detected between ventricular events sensed on left ventricular (LV) and right ventricular (RV) sensing channels. Preferred or optimal ventricular pacing delays are then determined, in part, based on a comparison of the relative degrees of variation obtained during the V sense test. In another example, during RV and LV pace tests, the device distinguishes QRS complexes arising due to interventricular conduction from QRS complexes arising due to atrioventricular conduction from the atria, so as to permit the determination of correct paced interventricular conduction delays for the patient. The paced interventricular conduction delays are also used to optimize ventricular pacing. Biventricular and monoventricular pacing regimes are provided.

A methods and devices for capture detection are based on sensing a propagated depolarization from a contralateral cardiac chamber. An intersite sensing interval is determined based on an intersite pacing delay and an intersite conduction delay associated with first and second pacing sites. Pacing pulses are delivered to the first pacing site and the second pacing site, the pacing pulses separated in time by the intersite pacing delay. An intersite sensing interval is timed. The process includes sensing, during the intersite sensing interval, at the first pacing site for a depolarization propagated to the first pacing site from the second pacing site. It a depolarization propagated from the second pacing site is not sensed, then capture of the first and second pacing sites is detected.

Techniques are provided for use by implantable medical devices for controlling ventricular pacing, particularly during atrial fibrillation. In one example, during a V sense test for use in optimizing ventricular pacing, the implantable device determines relative degrees of variation within antecedent and succedent intervals detected between ventricular events sensed on left ventricular (LV) and right ventricular (RV) sensing channels. Preferred or optimal ventricular pacing delays are then determined, in part, based on a comparison of the relative degrees of variation obtained during the V sense test. In another example, during RV and LV pace tests, the device distinguishes QRS complexes arising due to interventricular conduction from QRS complexes arising due to atrioventricular conduction from the atria, so as to permit the determination of correct paced interventricular conduction delays for the patient. The paced interventricular conduction delays are also used to optimize ventricular pacing. Biventricular and monoventricular pacing regimes are provided.

The invention relates to the field of non-linear photoconductive semiconductor switch parameter testing, in particular to a non-linear photoconductive semiconductor switch testing device and method. The non-linear photoconductive semiconductor switch testing device and method are provided for solving the problems existing in the prior art. Through cooperation of a delay synchronous machine, a laser, an optical fiber, a photoelectric probe, a first high-voltage probe and the like, the difficulty of conducting accurate testing on a non-linear photoconductive semiconductor switch on the high-voltage, high-current and ultrafast-pulse conditions is overcome, and accurate, convenient and reliable testing of the parameters such as the conduction delay time, jittering, the conduction resistance, the withstand voltage and the service life of the non-linear photoconductive semiconductor switch is realized. The device comprises the delay synchronous machine, the laser, the optical fiber, the photoelectric probe, high-voltage probes, an oscilloscope, a high-voltage pulse power source, Blumlein transmission wires, a matching load, an organic glass box, transformer insulating oil and limiting fixtures. The non-linear photoconductive semiconductor switch to be tested, the Blumlein transmission wires and the matching load are placed in the organic glass box and are immersed in the transformer insulating oil.

An LED tube lamp is disclosed. The LED tube lamp includes a lamp tube, a first external connection terminal and a second external connection terminal coupled to the lamp tube and for receiving an external driving signal, a rectifying circuit coupled to the first external connection terminal and the second external connection terminal and configured to rectify the external driving signal to produce a rectified signal, a filtering circuit coupled to the rectifying circuit and configured to filter the rectified signal to produce a filtered signal, an LED module coupled to the filtering circuit and configured to receive the filtered signal for emitting light; and a conduction-delaying circuit coupled to the rectifying circuit and comprising a conduction-delaying device, wherein the conduction-delaying circuit is configured such that when the external driving signal is initially input to the LED tube lamp, the conduction-delaying device is in an open-circuit state, and then the conduction-delaying device will enter a conducting state when voltage across the conduction-delaying device exceeds the conduction-delaying device's trigger voltage value, wherein the conducting state of the conduction-delaying device causes the LED module to conduct current for emitting light.

A method of stabilizing density wave oscillations in boiling water reactor cores is disclosed. The invention introduced a thin metallic fuel element made of fissile isotope baring metal encased and bonded with metallic cladding. The thin construction and the metallic material guarantee very short thermal time constant compared with the oscillation period. Although the feedback of the processes involved in density waves are negative, i.e. oppose any initial perturbation, sufficiently strong feedback may result in unstable behavior because of the time delay inherent in the propagation of the density wave and the heat conduction delay in the traditional fuel rods made of ceramic pellets encased in zircaloy tubes. The new fuel element of this invention introduces fast, not delayed, thermal energy to the coolant in response of any neutron flux perturbation, and thus introduces a stabilizing feedback. Boiling water reactor fuel bundles may benefit from this invention by including the new fuel element as part of its array of fuel rods, preferably filling in the space vacated by part-length fuel rods.

The invention discloses a current converting switch device applicable to a flexible direct current transmission direct current circuit breaker. A first main electrode and a second main electrode are located in a sealed cavity; the first main electrode is located above the second main electrode, and a gap is reserved between the first main electrode and the second main electrode; a groove is formedin the bottom of the second main electrode; the groove is filled with a macromolecular polymer ablation material; a discharge cavity is formed in a combination surface of the macromolecular polymer ablation material and the bottom of the groove; a hole is formed in the top of the discharge cavity; one end of a trigger electrode is connected with a trigger circuit, and the other end of the triggerelectrode penetrates through the macromolecular polymer ablation material and is inserted into the discharge cavity. The switch device is long in service life, simple in structure, relatively high intrigger conductivity, relatively low in trigger conduction delay and low in working coefficient.

A dimmable LED driving circuit belongs to the technical field of a semiconductor. The LED constant-current driving circuit comprises a silicon controlled rectifier dimming module, a constant-current rectification module, a power factor correction module, a filtering module and a circuit protection module, wherein the silicon controlled rectifier dimming module is used for changing conduction delay and the size of a conduction angle by changing a RW resistance value of a dimming potentiometer so that the duty ratio of a current passing through an LED is changed to affect the brightness of the LED; the structure of a traditional LED driving circuit is simplified by the constant-current rectification module comprising a high-reverse voltage-resistant current-constant device, so that the rectification function and the constant-current function are combined, a mains supply can be directly connected without additionally arranging other discrete constant-current devices to drive an LED lamp string; and excessive large current passing through the LED is prevented by using a polymeric positive temperature coefficient (PPTC) thermistor, and the LED lamp string cannot be damaged due to transient high voltage by a piezoresistor Rv. By the LED constant-current driving circuit, the functions of rectification, constant current and dimming are combined, the structure of the driving circuit is simplified, the miniaturization of the driving system can be achieved, and the cost is reduced.